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Profiling cellular phenotypes from microscopic imaging can provide meaningful biological information resulting from various factors affecting the cells. One motivating application is drug development: morphological cell features can be…

机器学习 · 统计学 2019-06-19 Gil Tabak , Minjie Fan , Samuel J. Yang , Stephan Hoyer , Geoff Davis

Quantitative phase imaging (QPI) is a label-free technique providing both morphology and quantitative biophysical information in biomedicine. However, applying such a powerful technique to in vivo pathological diagnosis remains challenging.…

Most approaches to the estimation of brain functional connectivity from the functional magnetic resonance imaging (fMRI) data rely on computing some measure of statistical dependence, or more generally, a distance between univariate…

计算机视觉与模式识别 · 计算机科学 2022-09-26 Oleg Kachan , Alexander Bernstein

Learning conditional densities and identifying factors that influence the entire distribution are vital tasks in data-driven applications. Conventional approaches work mostly with summary statistics, and are hence inadequate for a…

统计方法学 · 统计学 2022-09-13 Chengliang Tang , Nathan Lenssen , Ying Wei , Tian Zheng

Persistent homology offers a powerful tool for extracting hidden topological signals from brain networks. It captures the evolution of topological structures across multiple scales, known as filtrations, thereby revealing topological…

The mean field variational inference (MFVI) formulation restricts the general Bayesian inference problem to the subspace of product measures. We present a framework to analyze MFVI algorithms, which is inspired by a similar development for…

机器学习 · 统计学 2022-10-21 Soumyadip Ghosh , Yingdong Lu , Tomasz Nowicki , Edith Zhang

Gradient boosting is a sequential ensemble method that fits a new weaker learner to pseudo residuals at each iteration. We propose Wasserstein gradient boosting, a novel extension of gradient boosting that fits a new weak learner to…

统计方法学 · 统计学 2024-08-30 Takuo Matsubara

We propose a regression model for non-central $\chi$ (NC-$\chi$) distributed functional magnetic resonance imaging (fMRI) and diffusion weighted imaging (DWI) data, with the heteroscedastic Rician regression model as a prominent special…

应用统计 · 统计学 2016-12-22 Bertil Wegmann , Anders Eklund , Mattias Villani

This paper considers the problem of regression analysis with random covariance matrix as outcome and Euclidean covariates in the framework of Fr\'echet regression on the Bures-Wasserstein manifold. Such regression problems have many…

统计方法学 · 统计学 2024-09-17 Haoshu Xu , Hongzhe Li

Magnetic Resonance Imaging (MRI) is a principal diagnostic approach used in the field of radiology to create images of the anatomical and physiological structure of patients. MRI is the prevalent medical imaging practice to find…

计算机视觉与模式识别 · 计算机科学 2021-06-16 Yusuf Brima , Mossadek Hossain Kamal Tushar , Upama Kabir , Tariqul Islam

We develop a framework of canonical correlation analysis for distribution-valued functional data within the geometry of Wasserstein spaces. Specifically, we formulate an intrinsic concept of correlation between random distributions, propose…

统计方法学 · 统计学 2021-06-01 Hang Zhou , Zhenhua Lin , Fang Yao

We propose a Bayesian framework for uncertainty quantification and comparison in brain connectivity graph analysis. Standard graph-based approaches typically rely on point estimates of correlation matrices, overlooking the uncertainty…

统计方法学 · 统计学 2026-05-29 Alice Chevaux , Julyan Arbel , Guillaume Kon Kam King , Sophie Achard

Standard detection of evoked brain activity in functional MRI (fMRI) relies on a fixed and known shape of the impulse response of the neurovascular coupling, namely the hemodynamic response function (HRF). To cope with this issue, the joint…

应用统计 · 统计学 2015-01-07 Aina Frau-Pascual , Thomas Vincent , Florence Forbes , Philippe Ciuciu

Emotions are an essential part of human behavior that can impact thinking, decision-making, and communication skills. Thus, the ability to accurately monitor and identify emotions can be useful in many human-centered applications such as…

机器学习 · 计算机科学 2023-08-22 Nibraas Khan , Mahrukh Tauseef , Ritam Ghosh , Nilanjan Sarkar

Magnetic Resonance Imaging (MRI) is widely used in the pathological and functional studies of the brain, such as epilepsy, tumor diagnosis, etc. Automated accurate brain tissue segmentation like cerebro-spinal fluid (CSF), gray matter (GM),…

计算机视觉与模式识别 · 计算机科学 2018-08-07 Yao Sun , Yang Deng , Yue Xu , Shuo Zhang , Mingwang Zhu , Kehong Yuan

We study distribution-on-distribution regression problems in which a response distribution depends on multiple distributional predictors. Such settings arise naturally in applications where the outcome distribution is driven by several…

统计方法学 · 统计学 2026-01-08 Yuanying Chen , Tongyu Li , Yang Bai , Zhenhua Lin

Knowing how the Human brain is anatomically and functionally organized at the level of a group of healthy individuals or patients is the primary goal of neuroimaging research. Yet computing an average of brain imaging data defined over a…

计算机视觉与模式识别 · 计算机科学 2015-04-13 Alexandre Gramfort , Gabriel Peyré , Marco Cuturi

Assessing brain development for small infants is important for determining how the human brain grows during the early period of life when the rate of brain growth is at its peak. The development of MRI techniques has enabled the…

应用统计 · 统计学 2018-06-27 Alexander Petersen , Sean Deoni , Hans-Georg Müller

Quantile regression is useful for characterizing the conditional distribution of a response variable and understanding heterogeneity in the covariate effects at different quantiles. The rise of high-dimensional physiological data in…

统计方法学 · 统计学 2026-03-25 Yuanzhen Yue , Stella Self , Yichao Wu , Jiajia Zhang , Rahul Ghosal

We study the machine learning task for models with operators mapping between the Wasserstein space of probability measures and a space of functions, like e.g. in mean-field games/control problems. Two classes of neural networks, based on…

最优化与控制 · 数学 2023-09-19 Huyên Pham , Xavier Warin