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We investigate the propagation of uncertainties in the Aw-Rascle-Zhang model, which belongs to a class of second order traffic flow models described by a system of nonlinear hyperbolic equations. The stochastic quantities are expanded in…
Regularly varying stochastic processes model extreme dependence between process values at different locations and/or time points. For such processes we propose a two-step parameter estimation of the extremogram, when some part of the domain…
We study a spatial birth-and-death process on the phase space of locally finite configurations $\Gamma^+ \times \Gamma^-$ over $\mathbb{R}^d$. Dynamics is described by an non-equilibrium evolution of states obtained from the Fokker-Planck…
We introduce a family of discontinuous Galerkin methods to approximate the eigenvalues and eigenfunctions of a Stokes-Brinkman type of problem based in the interior penalty strategy. Under the standard assumptions on the meshes and a…
The phenotypic equilibrium, i.e. heterogeneous population of cancer cells tending to a fixed equilibrium of phenotypic proportions, has received much attention in cancer biology very recently. In previous literature, some theoretical models…
A recently developed measure-theoretic framework solves a stochastic inverse problem (SIP) for models where uncertainties in model output data are predominantly due to aleatoric (i.e., irreducible) uncertainties in model inputs (i.e.,…
In this paper we study a model describing the growth of necrotic tumors in different regimes of vascularisation. The tumor consists of a necrotic core of death cells and a surrounding nonnecrotic shell. The corresponding mathematical…
This paper presents an asymptotic preserving (AP) implicit-explicit (IMEX) scheme for solving the quantum BGK equation using the Hermite spectral method. The distribution function is expanded in a series of Hermite polynomials, with the…
We provide an overview of an optimal control problem within a stochastic model of tumor growth, which includes drug application. The model comprises two stochastic differential equations (SDE) representing the diffusion of nutrient and drug…
In this work we present a flexible tool for tumor progression, which simulates the evolutionary dynamics of cancer. Tumor progression implements a multi-type branching process where the key parameters are the fitness landscape, the mutation…
Cancer radiomics is an emerging discipline promising to elucidate lesion phenotypes and tumor heterogeneity through patterns of enhancement, texture, morphology, and shape. The prevailing technique for image texture analysis relies on the…
We investigate statistical properties of the optimal value of the Sample Average Approximation of stochastic programs, continuing the study in Kr\"atschmer (2023). Central Limit Theorem type results are derived for the optimal value. As a…
In this paper we study the "stiff pressure limit" of the porous medium equation, where the initial density is a bounded, integrable function with a sufficient decay at infinity. Our particular model, introduced by Perthame-Quiros-Vazquez,…
Accurate representation of atmosphere-ocean boundary layers, including the interplay of turbulence, surface waves, and air-sea fluxes, remains a challenge in geophysical fluid dynamics, particularly for climate simulations. This study…
Model predictive control is an advanced control approach for multivariable systems with constraints, which is reliant on an accurate dynamic model. Most real dynamic models are however affected by uncertainties, which can lead to…
In this paper we study the rigorous sharp interface limit of a diffuse interface model related to the dynamics of tumor growth, when a parameter $\epsilon$, representing the interface thickness between the tumorous and non tumorous cells,…
We study a tumor growth model in two space dimensions, where proliferation of the tumor cells leads to expansion of the tumor domain and migration of surrounding normal tissues into the exterior vacuum. The model features two moving…
Fatigue crack growth is one of the most common types of deterioration in metal structures with significant implications on their reliability. Recent advances in Structural Health Monitoring (SHM) have motivated the use of structural…
Mathematical and computational modelling in oncology has played an increasingly important role in not only understanding the impact of various approaches to treatment on tumour growth, but in optimizing dosing regimens and aiding the…
In this paper, we study a nonlinear free boundary problem modeling the growth of spherically symmetric tumors. The tumor consists of a central necrotic core, an intermediate annual quiescent-cell layer, and an outer proliferating-cell…