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Intra-cellular biochemical reactions exhibit a rich dynamical phenomenology which cannot be explained within the framework of mean-field rate equations and additive noise. Here, we show that the presence of metastable states and radically…

统计力学 · 物理学 2012-08-02 Tommaso Biancalani , Tim Rogers , Alan J. McKane

We study a stochastic two-species chemical reaction system with two mechanisms. One mechanism consists of chemical interactions which govern the overall drift of species amounts in the system; the other mechanism consists of resampling,…

概率论 · 数学 2014-05-06 John K. McSweeney , Lea Popovic

The two-population Kuramoto-Sakaguchi model for interacting populations of phase oscillators exhibits chimera states whereby one population is synchronised, and the other is desynchronised. Which of the two populations is synchronised…

适应与自组织系统 · 物理学 2026-02-19 Henry Irvine , Georg A. Gottwald

Cell systems consist of a huge number of various molecules that display specific patterns of interactions, which have a determining influence on the cell's functioning. In general, such complexity is seen to increase with the complexity of…

生物大分子 · 定量生物学 2014-03-14 Marianne Rooman , Jaroslav Albert , Mitia Duerinckx

Genetic switch systems with mutual repression of two transcription factors are studied using deterministic methods (rate equations) and stochastic methods (the master equation and Monte Carlo simulations). These systems exhibit bistability,…

分子网络 · 定量生物学 2007-05-23 Adiel Loinger , Azi Lipshtat , Nathalie Q. Balaban , Ofer Biham

The effect of stochasticity, in the form of Gaussian white noise, in a predator-prey model with two distinct time-scales is presented. A supercritical singular Hopf bifurcation yields a Type II excitability in the deterministic model. We…

动力系统 · 数学 2017-07-20 Susmita Sadhu

We investigate a type of bistability where noise not only causes transitions between stable states, but also constructs the states themselves. We focus on the experimentally well-studied system of ants choosing between two food sources to…

种群与进化 · 定量生物学 2015-06-16 Tommaso Biancalani , Louise Dyson , Alan J. McKane

Microbial populations in the natural environment are likely to experience growth conditions very different from those of a typical laboratory xperiment. In particular, removal rates of biomass and substrate are unlikely to be balanced under…

种群与进化 · 定量生物学 2015-05-18 Bhavin S. Khatri , Andrew Free , Rosalind J. Allen

We study the stability of non-conservative deterministic cross diffusion models and prove that they are approximated by stochastic population models when the populations become locally large. In this model, the individuals of two species…

偏微分方程分析 · 数学 2025-10-09 Vincent Bansaye , Alexandre Bertolino , Ayman Moussa

The totally asymmetric simple exclusion process (TASEP) is a paradigmatic stochastic model for non-equilibrium physics, and has been successfully applied to describe active transport of molecular motors along cytoskeletal filaments.…

生物物理 · 物理学 2018-07-25 Mareike Bojer , Isabella R. Graf , Erwin Frey

Species populations often modify their environment as they grow. When environmental feedback operates more slowly than population growth, the system can undergo boom-bust dynamics, where the population overshoots its carrying capacity and…

种群与进化 · 定量生物学 2026-05-27 Pablo Moreno-Spiegelberg , Javier Aguilar

We present a simple mathematical model that captures the evolutionary capabilities of a prebiotic compartment or protocell. In the model the protocell contains an autocatalytic set whose chemical dynamics is coupled to the growth-division…

种群与进化 · 定量生物学 2023-10-31 Angad Yuvraj Singh , Sanjay Jain

We consider the stochastic patterns of a system of communicating, or coupled, self-propelled particles in the presence of noise and communication time delay. For sufficiently large environmental noise, there exists a transition between a…

适应与自组织系统 · 物理学 2012-04-23 Luis Mier-y-Teran-Romero , Eric Forgoston , Ira B. Schwartz

The dynamics of a system formed by a finite number $N$ of globally coupled bistable oscillators and driven by external forces is studied focusing on a global variable defined as the arithmetic mean of each oscillator variable. Several…

统计力学 · 物理学 2009-11-13 David Cubero

We consider the dynamics of a population of organisms containing two mutually inhibitory gene regulatory networks, that can result in a bistable switch-like behaviour. We completely characterize their local and global dynamics in the…

分子网络 · 定量生物学 2016-10-07 Michael C. Mackey , Marta Tyran-Kaminska

We discuss a model of a system of interacting populations for the case when: (i) the growth rates and the coefficients of interaction among the populations depend on the populations densities: and (ii) the environment influences the growth…

混沌动力学 · 物理学 2013-11-15 Nikolay K. Vitanov , Kaloyan N. Vitanov

The purpose of this paper is to analyze the mechanism for the interplay of deterministic and stochastic models for contagious diseases. Deterministic models for contagious diseases are prone to predict global stability. Small natural birth…

种群与进化 · 定量生物学 2022-06-17 Torsten Lindström

Cellular transformations which involve a significant phenotypical change of the cell's state use bistable biochemical switches as underlying decision systems. In this work, we aim at linking cellular decisions taking place on a time scale…

细胞行为 · 定量生物学 2010-05-11 Steffen Waldherr , Jingbo Wu , Frank Allgöwer

One of the major challenges in neuroscience is to determine how noise that is present at the molecular and cellular levels affects dynamics and information processing at the macroscopic level of synaptically coupled neuronal populations.…

无序系统与神经网络 · 物理学 2014-06-12 Paul C. Bressloff , Jay M. Newby

Strong positive feedback is considered a necessary condition to observe abrupt shifts of ecosystems. A few previous studies have shown that demographic noise -- arising from the probabilistic and discrete nature of birth and death processes…

种群与进化 · 定量生物学 2021-06-22 Sabiha Majumder , Ayan Das , Appilineni Kushal , Sumithra Sankaran , Vishwesha Guttal
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