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Longitudinal studies are frequently used in medical research and involve collecting repeated measures on individuals over time. Observations from the same individual are invariably correlated and thus an analytic approach that accounts for…

We investigate the problem of calibration and assessment of predictive rules in prognostic designs when missing values are present in the predictors. Our paper has two key objectives which are entwined. The first is to investigate how the…

统计方法学 · 统计学 2018-10-12 B. J. A. Mertens , E. Banzato , L. C. de Wreede

There is a long history of devleopment of methodology dealing with missing data in statistical analysis. Today, the most popular methods fall into two classes, Complete Cases (CC) and Multiple Imputation (MI). Another approach, Available…

统计方法学 · 统计学 2015-09-17 Xiao Gu , Norman Matloff

International comparisons of hierarchical time series data sets based on survey data, such as annual country-level estimates of school enrollment rates, can suffer from large amounts of missing data due to differing coverage of surveys…

统计方法学 · 统计学 2025-03-31 Daphne H. Liu , Adrian E. Raftery

Most recent network failure diagnosis systems focused on data center networks where complex measurement systems can be deployed to derive routing information and ensure network coverage in order to achieve accurate and fast fault…

网络与互联网体系结构 · 计算机科学 2022-07-06 Yufeng Xin , Shih-Wen Fu , Anirban Mandal , Ryan Tanaka , Mats Rynge , Karan Vahi , Ewa Deelman

A method using multiple imputation and bootstrap for dealing with missing data in mediation analysis is introduced and implemented in SAS. Through simulation studies, it is shown that the method performs well for both MCAR and MAR data…

统计方法学 · 统计学 2014-01-10 Lijuan Wang , Zhiyong Zhang , Xin Tong

Imputing missing values is common practice in label-free quantitative proteomics. Imputation aims at replacing a missing value with a user-defined one. However, the imputation itself may not be optimally considered downstream of the…

统计方法学 · 统计学 2022-09-08 Marie Chion , Christine Carapito , Frédéric Bertrand

Multiple imputation provides an effective way to handle missing data. When several possible models are under consideration for the data, the multiple imputation is typically performed under a single-best model selected from the candidate…

统计方法学 · 统计学 2018-11-30 Gyuhyeong Goh , Jae Kwang Kim

Unobserved confounding is common in many applications, making causal inference from observational data challenging. As a remedy, causal sensitivity analysis is an important tool to draw causal conclusions under unobserved confounding with…

It is argued that the Calibrated Bayesian (CB) approach to statistical inference capitalizes on the strength of Bayesian and frequentist approaches to statistical inference. In the CB approach, inferences under a particular model are…

统计方法学 · 统计学 2011-08-10 Roderick Little

Observational studies provide invaluable opportunities to draw causal inference, but they may suffer from biases due to pretreatment difference between treated and control units. Matching is a popular approach to reduce observed covariate…

统计方法学 · 统计学 2025-09-17 Xinran Li

Return-to-baseline is an important method to impute missing values or unobserved potential outcomes when certain hypothetical strategies are used to handle intercurrent events in clinical trials. Current return-to-baseline approaches seen…

统计方法学 · 统计学 2021-11-19 Yongming Qu , Biyue Dai

In this work, we propose an approach for assessing sensitivity to unobserved confounding in studies with multiple outcomes. We demonstrate how prior knowledge unique to the multi-outcome setting can be leveraged to strengthen causal…

统计方法学 · 统计学 2023-01-26 Jiajing Zheng , Jiaxi Wu , Alexander D'Amour , Alexander Franks

In many applications of causal inference, the treatment received by one unit may influence the outcome of another, a phenomenon referred to as interference. Although there are several frameworks for conducting causal inference in the…

统计方法学 · 统计学 2025-11-27 Matvey Ortyashov , AmirEmad Ghassami

Marginal structural models (MSMs) are commonly used to estimate causal intervention effects in longitudinal non-randomised studies. A common issue when analysing data from observational studies is the presence of incomplete confounder data,…

统计方法学 · 统计学 2019-12-02 Clemence Leyrat , James R Carpenter , Sebastien Bailly , Elizabeth J Willamson

Advancements in data collection techniques and the heterogeneity of data resources can yield high percentages of missing observations on variables, such as block-wise missing data. Under missing-data scenarios, traditional methods such as…

统计方法学 · 统计学 2022-05-17 Wei Lan , Xuerong Chen , Tao Zou , Chih-Ling Tsai

Case-cohort studies are conducted within cohort studies, wherein collection of exposure data is limited to a subset of the cohort, leading to a large proportion of missing data by design. Standard analysis uses inverse probability weighting…

Multiple imputation (MI) is a popular method for handling missing data. Auxiliary variables can be added to the imputation model(s) to improve MI estimates. However, the choice of which auxiliary variables to include in the imputation model…

Multiple imputation is a highly recommended technique to deal with missing data, but the application to longitudinal datasets can be done in multiple ways. When a new wave of longitudinal data arrives, we can treat the combined data of…

统计方法学 · 统计学 2026-05-18 X. M. Kavelaars , S. van Buuren , J. R. van Ginkel

Causal inference necessarily relies upon untestable assumptions; hence, it is crucial to assess the robustness of obtained results to violations of identification assumptions. However, such sensitivity analysis is only occasionally…

统计方法学 · 统计学 2025-05-19 Tobias Freidling , Qingyuan Zhao