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Joint modeling of spatially-oriented dependent variables is commonplace in the environmental sciences, where scientists seek to estimate the relationships among a set of environmental outcomes accounting for dependence among these outcomes…

统计方法学 · 统计学 2021-03-22 Lu Zhang , Sudipto Banerjee , Andrew O. Finley

Probabilistic and set-based methods are two approaches for model invalidation, parameter and state estimation. Both classes of methods use different types of data, i.e. deterministic or probabilistic data, which allow different statements…

最优化与控制 · 数学 2013-11-28 Stefan Streif , Didier Henrion , Rolf Findeisen

Positron emission tomography (PET) is an important functional medical imaging technique often used in the evaluation of certain brain disorders, whose reconstruction problem is ill-posed. The vast majority of reconstruction methods in PET…

图像与视频处理 · 电气工程与系统科学 2023-06-09 Tin Vlašić , Tomislav Matulić , Damir Seršić

Probabilistic Manifold Decomposition (PMD)\cite{doi:10.1137/25M1738863}, developed in our earlier work, provides a nonlinear model reduction by embedding high-dimensional dynamics onto low-dimensional probabilistic manifolds. The PMD has…

数值分析 · 数学 2026-01-13 Jiaming Guo , Dunhui Xiao

The use of genetic variants as instrumental variables - an approach known as Mendelian randomization - is a popular epidemiological method for estimating the causal effect of an exposure (phenotype, biomarker, risk factor) on a disease or…

统计方法学 · 统计学 2020-12-21 Ioan Gabriel Bucur , Tom Claassen , Tom Heskes

In many modern regression applications, the response consists of multiple categorical random variables whose probability mass is a function of a common set of predictors. In this article, we propose a new method for modeling such a…

统计方法学 · 统计学 2024-05-15 Aaron J. Molstad , Xin Zhang

This article focuses on covariance estimation for multi-study data. Popular approaches employ factor-analytic terms with shared and study-specific loadings that decompose the variance into (i) a shared low-rank component, (ii)…

统计方法学 · 统计学 2026-01-26 Lorenzo Mauri , Niccolò Anceschi , David B. Dunson

We propose a Bayesian tensor regression model to accommodate the effect of multiple factors on phenotype prediction. We adopt a set of prior distributions that resolve identifiability issues that may arise between the parameters in the…

机器学习 · 统计学 2025-11-04 Antonia A. L. Dos Santos , Danilo A. Sarti , Rafael A. Moral , Andrew C. Parnell

Longitudinal processes are often associated with each other over time; therefore, it is important to investigate the associations among developmental processes and understand their joint development. The latent growth curve model (LGCM)…

统计方法学 · 统计学 2025-12-02 Jin Liu

The results from Genome-Wide Association Studies (GWAS) on thousands of phenotypes provide an unprecedented opportunity to infer the causal effect of one phenotype (exposure) on another (outcome). Mendelian randomization (MR), an…

统计方法学 · 统计学 2019-04-30 Jia Zhao , Jingsi Ming , Xianghong Hu , Gang Chen , Jin Liu , Can Yang

Bayesian models of behavior have provided computational level explanations in a range of psychophysical tasks. One fundamental experimental paradigm is the production or reproduction task, in which subjects are instructed to generate an…

机器学习 · 计算机科学 2022-01-03 Nils Neupärtl , Constantin A. Rothkopf

We propose a new model selection method, the posterior averaging information criterion, for Bayesian model assessment from a predictive perspective. The theoretical foundation is built on the Kullback-Leibler divergence to quantify the…

统计方法学 · 统计学 2020-09-22 Shouhao Zhou

Despite exceptional predictive performance of Deep sequence models (DSMs), the main concern of their deployment centers around the lack of uncertainty awareness. In contrast, probabilistic models quantify the uncertainty associated with…

机器学习 · 计算机科学 2026-03-03 Wenlong Chen

Implicit stochastic models, where the data-generation distribution is intractable but sampling is possible, are ubiquitous in the natural sciences. The models typically have free parameters that need to be inferred from data collected in…

机器学习 · 统计学 2020-08-17 Steven Kleinegesse , Michael U. Gutmann

We present a flexible Bayesian semiparametric mixed model for longitudinal data analysis in the presence of potentially high-dimensional categorical covariates. Building on a novel hidden Markov tensor decomposition technique, our proposed…

统计方法学 · 统计学 2022-08-05 Giorgio Paulon , Peter Müller , Abhra Sarkar

We address the problem of two-variable causal inference without intervention. This task is to infer an existing causal relation between two random variables, i.e. $X \rightarrow Y$ or $Y \rightarrow X$ , from purely observational data. As…

机器学习 · 统计学 2020-01-07 Maximilian Kurthen , Torsten A. Enßlin

We develop a Bayesian approach to predict a continuous or binary outcome from data that are collected from multiple sources with a multi-way (i.e.. multidimensional tensor) structure. As a motivating example we consider molecular data from…

统计方法学 · 统计学 2022-08-09 Jonathan Kim , Brian J. Sandri , Raghavendra B. Rao , Eric F. Lock

We tackle the problem of multiscale regression for predictors that are spatially or temporally indexed, or with a pre-specified multiscale structure, with a Bayesian modular approach. The regression function at the finest scale is expressed…

统计方法学 · 统计学 2018-09-18 Michele Peruzzi , David B. Dunson

Modern biomedicine is challenged to predict the effects of genetic variation. Systematic functional assays of point mutants of proteins have provided valuable empirical information, but vast regions of sequence space remain unexplored.…

生物大分子 · 定量生物学 2017-01-18 Thomas A. Hopf , John B. Ingraham , Frank J. Poelwijk , Michael Springer , Chris Sander , Debora S. Marks

Measuring the impact of an environmental point source exposure on the risk of disease, like cancer or childhood asthma, is well-developed. Modeling how an environmental health hazard that is extensive in space, like a wastewater canal,…

统计方法学 · 统计学 2024-07-29 Rob Trangucci , Jesse Contreras , Jon Zelner , Joseph N. S. Eisenberg , Yang Chen