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Algorithms which compute locally optimal continuous designs often rely on a finite design space or on repeatedly solving a complex non-linear program. Both methods require extensive evaluations of the Jacobian Df of the underlying model.…

统计方法学 · 统计学 2021-01-18 Philipp Seufert , Jan Schwientek , Michael Bortz

This paper considers optimal input design when the intended use of the identified model is to construct a feed-forward controller based on measurable disturbances. The objective is to find a minimum power excitation signal to be used in…

系统与控制 · 计算机科学 2013-03-14 Per Hägg , Bo Wahlberg

Two useful strategies to speed up drug development are to increase the patient accrual rate and use novel adaptive designs. Unfortunately, these two strategies often conflict when the evaluation of the outcome cannot keep pace with the…

统计方法学 · 统计学 2018-07-24 Ruitao Lin , Ying Yuan

In the fashion industry, order scheduling focuses on the assignment of production orders to appropriate production lines. In reality, before a new order can be put into production, a series of activities known as pre-production events need…

人工智能 · 计算机科学 2017-02-02 Wei Du , Yang Tang , Sunney Yung Sun Leung , Le Tong , Athanasios V. Vasilakos , Feng Qian

Discrete choice experiments are frequently used to quantify consumer preferences by having respondents choose between different alternatives. Choice experiments involving mixtures of ingredients have been largely overlooked in the…

统计方法学 · 统计学 2021-09-15 Mario Becerra , Peter Goos

We consider the problem of designing experiments for investigating particle in-flight properties in thermal spraying. Observations are available on an extensive design for an initial day and thereafter in limited number for any particular…

应用统计 · 统计学 2013-12-17 Holger Dette , Laura Hoyden , Sonja Kuhnt , Kirsten Schorning

A/B testing is critical for modern technological companies to evaluate the effectiveness of newly developed products against standard baselines. This paper studies optimal designs that aim to maximize the amount of information obtained from…

统计方法学 · 统计学 2023-11-07 Ting Li , Chengchun Shi , Jianing Wang , Fan Zhou , Hongtu Zhu

This paper presents a quasi-sequential optimal design framework for toxicology experiments, specifically applied to sea urchin embryos. The authors propose a novel approach combining robust optimal design with adaptive, stage-based testing…

统计方法学 · 统计学 2025-03-04 Elvis Han Cui , Michael Collins , Jessica Munson , Weng Kee Wong

Cumulative link models have been widely used for ordered categorical responses. Uniform allocation of experimental units is commonly used in practice, but often suffers from a lack of efficiency. We consider D-optimal designs with ordered…

统计理论 · 数学 2017-11-09 Jie Yang , Liping Tong , Abhyuday Mandal

Complete reliance on the fitted model in response surface experiments is risky and relaxing this assumption, whether out of necessity or intentionally, requires an experimenter to account for multiple conflicting objectives. This work…

统计方法学 · 统计学 2023-06-16 Olga Egorova , Steven G. Gilmour

This paper examines common assumptions regarding the decision-making internal environment for intelligent agents and investigates issues related to processing of memory and belief states to help obtain better understanding of the responses.…

人工智能 · 计算机科学 2018-04-10 Subhash Kak

In real life situations often paired comparisons involving alternatives of either full or partial profiles to mitigate cognitive burden are presented. For this situation the problem of finding optimal designs is considered in the presence…

统计方法学 · 统计学 2021-10-20 Eric Nyarko

Complex Ornstein-Uhlenbeck (OU) processes have various applications in statistical modelling. They play role e.g. in the description of the motion of a charged test particle in a constant magnetic field or in the study of rotating waves in…

统计理论 · 数学 2018-08-13 Sándor Baran , Csilla Szák-Kocsis , Milan Stehlík

In clinical trials, the response of a given subject often depends on the selected treatment as well as on some covariates. We study optimal approximate designs of experiments in the models with treatment and covariate effects. We allow for…

统计理论 · 数学 2019-07-10 Samuel Rosa

Defining an effective way to design stable emulsions with limited resources is a challenge that every laboratory is facing at least once. Two ways of experiments have been trending as a cost-and-time-efficient method to explore factor…

化学物理 · 物理学 2021-10-29 Natacha Guyader , Magalie Michiel , Vincent Cobut , Stephane Serfaty

Systems with both quantitative and qualitative responses are widely encountered in many applications. Design of experiment methods are needed when experiments are conducted to study such systems. Classic experimental design methods are…

统计方法学 · 统计学 2023-04-24 Lulu Kang , Xinwei Deng , Ran Jin

A micro-scale model is proposed for the evolution of the limit order book. Within this model, the flows of orders (claims) are described by doubly stochastic Poisson processes taking account of the stochastic character of intensities of bid…

概率论 · 数学 2014-12-09 V. Yu. Korolev , A. V. Chertok , A. Yu. Korchagin , A. I. Zeifman

Experiments deliver credible treatment-effect estimates but, because they are costly, are often restricted to specific sites, small populations, or particular mechanisms. A common practice across several fields is therefore to combine…

计量经济学 · 经济学 2025-12-30 Aristotelis Epanomeritakis , Davide Viviano

Classical approaches to experimental design assume that intervening on one unit does not affect other units. There are many important settings, however, where this non-interference assumption does not hold, as when running experiments on…

最优化与控制 · 数学 2020-07-01 Stefan Wager , Kuang Xu

In this paper, we study the design and analysis of experiments conducted on a set of units over multiple time periods where the starting time of the treatment may vary by unit. The design problem involves selecting an initial treatment time…

计量经济学 · 经济学 2023-09-27 Ruoxuan Xiong , Susan Athey , Mohsen Bayati , Guido Imbens