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相关论文: Coarsening dynamics of chemotactic aggregates

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We derive general kinetic and hydrodynamic models of chemotactic aggregation that describe certain features of the morphogenesis of biological colonies (like bacteria, amoebae, endothelial cells or social insects). Starting from a…

生物物理 · 物理学 2009-11-13 Pierre-Henri Chavanis , Clement Sire

A generically observed mechanism that drives the self-organization of living systems is interaction via chemical signals among the individual elements -- which may represent cells, bacteria, or even enzymes. Here we propose a novel…

We consider a generalized class of Keller-Segel models describing the chemotaxis of biological populations (bacteria, amoebae, endothelial cells, social insects,...). We show the analogy with nonlinear mean field Fokker-Planck equations and…

生物物理 · 物理学 2016-11-23 Pierre-Henri Chavanis

The Keller-Segel model is a system of partial differential equations modelling chemotactic aggregation in cellular systems. This model has blowing up solutions for large enough initial conditions in dimensions d >= 2, but all the solutions…

偏微分方程分析 · 数学 2009-11-11 Carlos Escudero

While the role of local interactions in nonequilibrium phase transitions is well studied, a fundamental understanding of the effects of long-range interactions is lacking. We study the critical dynamics of reproducing agents subject to…

Chemical signaling is one of the ubiquitous mechanisms by which inter-cellular communication takes place at the microscopic level, particularly via chemotaxis. Such multi-cellular systems are popularly studied using continuum, mean-field…

细胞行为 · 定量生物学 2009-11-11 Ramon Grima

In this paper, we focus on the Keller-Segel chemotaxis system in a random heterogeneous domain. We assume that the corresponding diffusion and chemotaxis coefficients are given by stationary ergodic random fields and apply stochastic…

偏微分方程分析 · 数学 2016-09-16 Anastasios Matzavinos , Mariya Ptashnyk

Cells encounter a diverse array of physical and chemical signals as they navigate their natural surroundings. However, their response to the simultaneous presence of multiple cues remains elusive. Particularly, the impact of topography…

偏微分方程分析 · 数学 2026-03-10 Valeria Cuentas , Elio Espejo

This paper deals with the analysis of qualitative properties involved in the dynamics of Keller-Segel type systems in which the diffusion mechanisms of the cells are driven by porous-media flux-saturated phenomena. We study the…

偏微分方程分析 · 数学 2018-10-18 Margarita Arias , Juan Campos , Juan Soler

In this paper, we propose and study a stochastic aggregation-diffusion equation of the Keller-Segel (KS) type for modeling the chemotaxis in dimensions $d=2,3$. Unlike the classical deterministic KS system, which only allows for…

偏微分方程分析 · 数学 2020-09-23 Hui Huang , Jinniao Qiu

We study the Keller-Segel model of chemotaxis and develop a composite particle-grid numerical method with adaptive time stepping which allows us to accurately resolve singular solutions. The numerical findings (in two dimensions) are then…

偏微分方程分析 · 数学 2013-02-20 Ibrahim Fatkullin

Biological tissues have been observed to display emergent fluid-like properties, owing to physical interactions between cells. However, it remains unclear in general how these fluid-like properties affect tissue structure and function.…

软凝聚态物质 · 物理学 2026-02-24 Giulia L. Celora , Benjamin J. Walker , Mohit P. Dalwadi , Philip Pearce

Chemotaxis plays a significant role in numerous physiological processes. The Keller-Segel equation serves as a mathematical model for simulating the phenomenon of cell population aggregation under chemotaxis, possessing physical properties…

数值分析 · 数学 2025-02-24 Mingmei Chen , Kun Wang , Cong Xie

Chemotaxis is a fundamental guidance mechanism of cells and organisms, responsible for attracting microbes to food, embryonic cells into developing tissues, immune cells to infection sites, animals towards potential mates, and…

定量方法 · 定量生物学 2018-06-26 K. J. Painter

The Keller-Segel model is a system of partial differential equations that describes the movement of cells or organisms in response to chemical signals, a phenomenon known as chemotaxis. In this study, we analyze a doubly parabolic…

偏微分方程分析 · 数学 2025-03-27 Anne Caroline Bronzi , Crystianne Lilian de Andrade

Chemotaxis describes the movement of an organism, such as single or multi-cellular organisms and bacteria, in response to a chemical stimulus. Two widely used models to describe the phenomenon are the celebrated Keller-Segel equation and a…

偏微分方程分析 · 数学 2024-01-11 Kathrin Hellmuth , Christian Klingenberg , Qin Li , Min Tang

Microorganisms can preferentially orient and move along gradients of a chemo-attractant (i.e., chemotax) while colonies of many microorganisms can collectively undergo complex dynamics in response to chemo-attractants that they themselves…

生物物理 · 物理学 2013-10-30 Enkeleida Lushi , Raymond E. Goldstein , Michael J. Shelley

The construction of coarse-grained descriptions of a system's kinetics is well established in biophysics. One prominent example is Markov state models in protein folding dynamics. In this paper, we develop a coarse-grained, discrete state…

软凝聚态物质 · 物理学 2024-12-23 Salman Fariz Navas , Sabine H. L. Klapp

We use extreme value statistics to study the dynamics of coarsening in aggregation-fragmentation models which form condensates in the steady state. The dynamics is dominated by the formation of local condensates on a coarsening length scale…

统计力学 · 物理学 2023-03-27 Chandrashekar Iyer , Arghya Das , Mustansir Barma

Coarsening, the process where larger structures grow at the expense of smaller ones, is a fundamental aspect of multiphase systems. The cell cytoplasm exemplifies an out-of-equilibrium multiphase system, where phase-separated condensates…