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相关论文: Mobility-GCN: a human mobility-based graph convolu…

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In many different fields interactions between objects play a critical role in determining their behavior. Graph neural networks (GNNs) have emerged as a powerful tool for modeling interactions, although often at the cost of adding…

计算机视觉与模式识别 · 计算机科学 2022-06-09 Zhaoen Su , Chao Wang , David Bradley , Carlos Vallespi-Gonzalez , Carl Wellington , Nemanja Djuric

Particle flows in spatial networks are susceptible to congestion. In this paper, we analyze the phase transitions of these networks to a state of congested transport and the influence of both topology and spatial dynamics on its emergence.…

物理与社会 · 物理学 2015-01-07 Serdar Colak , Christian M. Schneider , Pu Wang , Marta C. Gonzalez

Human Mobility has attracted attentions from different fields of studies such as epidemic modeling, traffic engineering, traffic prediction and urban planning. In this survey we review major characteristics of human mobility studies…

社会与信息网络 · 计算机科学 2013-07-04 Fereshteh Asgari , Vincent Gauthier , Monique Becker

The use of multiple drugs accounts for almost 30% of all hospital admission and is the 5th leading cause of death in America. Since over 30% of all adverse drug events (ADEs) are thought to be caused by drug-drug interactions (DDI), better…

定量方法 · 定量生物学 2020-09-02 Ricky Wang

We propose a new stochastic emergency network design model that uses a fleet of drones to quickly deliver naxolone in response to opioid overdoses. The network is represented as a collection of M/G/K queuing systems in which the capacity K…

最优化与控制 · 数学 2024-01-29 Miguel Lejeune , Wenbo Ma

The ongoing opioid crisis highlights the urgent need for novel therapeutic strategies that can be rapidly deployed. This study presents a novel approach to identify potential repurposable drugs for the treatment of opioid addiction, aiming…

分子网络 · 定量生物学 2025-09-25 Chunhuan Zhang , Sean Cottrell , Benjamin Jones , Yueying Zhu , Huahai Qiu , Bengong Zhang , Tianshou Zhou , Jian Jiang

In this paper, we consider an opioid epidemic dynamical model with random perturbation that typically describes the interplay between regular prescription use, addictive use, and the process of rehabilitation from addiction and vice-versa.…

最优化与控制 · 数学 2018-06-19 Getachew K. Befekadu , Quanyan Zhu

Complex or co-existing diseases are commonly treated using drug combinations, which can lead to higher risk of adverse side effects. The detection of polypharmacy side effects is usually done in Phase IV clinical trials, but there are still…

机器学习 · 统计学 2019-05-03 Andreea Deac , Yu-Hsiang Huang , Petar Veličković , Pietro Liò , Jian Tang

The conceptual structure of opioids, based on the bibliometric analysis of 4,935 articles of the Web of Science was constructed. The results were processed identifying the most cited articles to extract the main connections and frequencies…

数字图书馆 · 计算机科学 2020-03-31 C. Aguado , A. Silva , V. M. Castano

Opioid Use Disorder (OUD) is a public health crisis costing the US billions of dollars annually in healthcare, lost workplace productivity, and crime. Analyzing longitudinal healthcare data is critical in addressing many real-world problems…

The dearth of prescribing guidelines for physicians is one key driver of the current opioid epidemic in the United States. In this work, we analyze medical and pharmaceutical claims data to draw insights on characteristics of patients who…

Preoperative opioid use has been reported to be associated with higher preoperative opioid demand, worse postoperative outcomes, and increased postoperative healthcare utilization and expenditures. Understanding the risk of preoperative…

机器学习 · 计算机科学 2022-05-18 Yuming Sun , Jian Kang , Chad Brummett , Yi Li

We propose an end-to-end model to predict drug-drug interactions (DDIs) by employing graph-augmented convolutional networks. And this is implemented by combining graph CNN with an attentive pooling network to extract structural relations…

机器学习 · 计算机科学 2025-07-01 Yi Zhong , Xueyu Chen , Yu Zhao , Xiaoming Chen , Tingfang Gao , Zuquan Weng

Meta-population networks are effective tools for capturing population movement across distinct regions, but the assumption of well-mixed regions fails to capture the reality of population higher-order interactions. As a multidimensional…

物理与社会 · 物理学 2024-06-18 Yanyi Nie , Yanbing Liu , Qixuan Cao , Tao Lin , Wei Wang

County-level estimates of opioid use disorder (OUD) are essential for understanding the influence of local economic and social conditions. They provide policymakers with the granular information needed to identify, target, and implement…

Accurate traffic forecasting is essential for smart cities to achieve traffic control, route planning, and flow detection. Although many spatial-temporal methods are currently proposed, these methods are deficient in capturing the…

机器学习 · 计算机科学 2024-03-07 Aoyu Liu , Yaying Zhang

This research set out to explore and delineate spatial patterns and mortality distributions for various cancer types across U.S. states between 1999 and 2021. The aim was to uncover region-specific cancer burdens and inform geographically…

应用统计 · 统计学 2025-08-19 E. Kubuafor , D. Baidoo , A. Duah , R. Amevor , O. J. Okeke , D. Quaye , P. O. Appiah

Sickle Cell Disease (SCD) is a chronic genetic disorder characterized by recurrent acute painful episodes. Opioids are often used to manage these painful episodes; the extent of their use in managing pain in this disorder is an issue of…

人工智能 · 计算机科学 2023-10-11 Swati Padhee , Tanvi Banerjee , Daniel M. Abrams , Nirmish Shah

Accurately forecasting transportation demand is crucial for efficient urban traffic guidance, control and management. One solution to enhance the level of prediction accuracy is to leverage graph convolutional networks (GCN), a neural…

机器学习 · 计算机科学 2021-07-08 Zhengyong Chen , Hongde Wu , Noel E. O'Connor , Mingming Liu

Recent advances and achievements of artificial intelligence (AI) as well as deep and graph learning models have established their usefulness in biomedical applications, especially in drug-drug interactions (DDIs). DDIs refer to a change in…