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Human mobility is crucial to understand the transmission pattern of COVID-19 on spatially embedded geographic networks. This pattern seems unpredictable, and the propagation appears unstoppable, resulting in over 350,000 death tolls in the…

物理与社会 · 物理学 2022-01-19 Hengfang Deng , Jianxi Gao , Qi Wang

Opioid and substance misuse is rampant in the United States today, with the phenomenon known as the opioid crisis. The relationship between substance use and mental health has been extensively studied, with one possible relationship being…

The United States is experiencing an opioid epidemic, and there were more than 10 million opioid misusers aged 12 or older each year. Identifying patients at high risk of Opioid Use Disorder (OUD) can help to make early clinical…

The United States is currently experiencing an unprecedented opioid crisis, and opioid overdose has become a leading cause of injury and death. Effective opioid addiction recovery calls for not only medical treatments, but also behavioral…

社会与信息网络 · 计算机科学 2019-12-04 Zhou Yang , Spencer Bradshaw , Rattikorn Hewett , Fang Jin

Motivation: Opioid use disorder (OUD) often arises after prescription opioid exposure and follows transitions among onset, remission, and relapse. Linked EHR-survey resources such as the All of Us Research Program enable stage-specific risk…

定量方法 · 定量生物学 2026-01-23 Mengman Wei , Stanislav Listopad , Qian Peng

Drug synergy arises when the combined impact of two drugs exceeds the sum of their individual effects. While single-drug effects on cell lines are well-documented, the scarcity of data on drug synergy, considering the vast array of…

Understanding how urban socio-demographic and environmental factors relate with health is essential for public health and urban planning. However, traditional statistical methods struggle with nonlinear effects, while machine learning…

机器学习 · 计算机科学 2025-08-05 Minwei Zhao , Sanja Scepanovic , Stephen Law , Ivica Obadic , Cai Wu , Daniele Quercia

Responding to the U.S. opioid crisis requires a holistic approach supported by evidence from linking and analyzing multiple data sources. This paper discusses how 20 available resources can be combined to answer pressing public health…

计量经济学 · 经济学 2021-02-11 Olga Scrivner , Elizabeth McAvoy , Thuy Nguyen , Tenzin Choeden , Kosali Simon , Katy Börner

Addiction epidemiology has been an active area of mathematical research in recent years. However, the social and mental processes involved in substance use disorders versus contraction of a pathogenic disease have presented challenges to…

物理与社会 · 物理学 2022-02-25 Owen Queen , Vincent Jodoin , Leigh B. Pearcy , W. Christopher Strickland

Opioid addiction is a severe public health threat in the U.S, causing massive deaths and many social problems. Accurate relapse prediction is of practical importance for recovering patients since relapse prediction promotes timely relapse…

社会与信息网络 · 计算机科学 2018-11-30 Zhou Yang , Long Nguyen , Fang Jin

Opiates are some of the most effective pain relief medications available for patients suffering from cancer and surgery-related pain. Despite the affordability and effectiveness of these medications, access to opiates is highly…

应用统计 · 统计学 2016-12-05 Kris Sankaran , Suzanne Tamang , Ami Bhatt

Understanding dynamic human mobility changes and spatial interaction patterns at different geographic scales is crucial for assessing the impacts of non-pharmaceutical interventions (such as stay-at-home orders) during the COVID-19…

社会与信息网络 · 计算机科学 2020-11-03 Yuhao Kang , Song Gao , Yunlei Liang , Mingxiao Li , Jinmeng Rao , Jake Kruse

Drug combinations are frequently used for the treatment of cancer patients in order to increase efficacy, decrease adverse side effects, or overcome drug resistance. Given the enormous number of drug combinations, it is cost- and…

分子网络 · 定量生物学 2021-02-18 Peiran Jiang , Shujun Huang , Zhenyuan Fu , Zexuan Sun , Ted M. Lakowski , Pingzhao Hu

Vicodin is the most commonly prescribed pain reliever in the United States. Research indicates that there are two million people who are currently abusing Vicodin, and the majority of those who abuse Vicodin were initially exposed to it via…

其他定量生物学 · 定量生物学 2013-08-19 Wendy K. Caldwell , Benjamin Freedman , Luke Settles , Michael M. Thomas , Anarina Murillo , Erika Camacho , Stephen Wirkus

The opioid epidemic continues to ravage communities worldwide, straining healthcare systems, disrupting families, and demanding urgent computational solutions. To combat this lethal opioid crisis, graph learning methods have emerged as a…

机器学习 · 计算机科学 2026-02-17 Tianyi Ma , Yiyang Li , Yiyue Qian , Zheyuan Zhang , Zehong Wang , Chuxu Zhang , Yanfang Ye

Ischaemic heart disease (IHD) remains the primary cause of mortality in the US. This study focuses on using spatio-temporal disease mapping models to explore the temporal trends of IHD at the county level from 1999 to 2021. To manage the…

应用统计 · 统计学 2024-12-10 A. Urdangarin , T. Goicoa , P. Congdon , MD. Ugarte

Introduction: Chronic pain patients are at increased risk of opioid-misuse. Less is known about the unique risk conferred by each pain-management treatment, as treatments are typically implemented together, confounding their independent…

The opioid epidemic began with prescription pain relievers. In 2010 Purdue Pharma reformulated OxyContin to make it more difficult to abuse. OxyContin misuse fell dramatically, and concurrently heroin deaths began to rise. Previous research…

综合经济学 · 经济学 2021-01-28 Shiyu Zhang , Daniel Guth

Drug-induced parkinsonism affects many older adults with dementia, often causing gait disturbances. New advances in vision-based human pose-estimation have opened possibilities for frequent and unobtrusive analysis of gait in residential…

计算机视觉与模式识别 · 计算机科学 2021-10-05 Andrea Sabo , Sina Mehdizadeh , Andrea Iaboni , Babak Taati

The opioid epidemic remains a major public health challenge in the United States, requiring a multi-pronged intervention approach to mitigate harms to communities. Given the heterogeneity of the epidemic across the country, it is crucial…

应用统计 · 统计学 2026-04-13 Abdulrahman A. Ahmed , M. Amin Rahimian , Qiushi Chen , Praveen Kumar