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Current techniques in sequencing a genome allow a service provider (e.g. a sequencing company) to have full access to the genome information, and thus the privacy of individuals regarding their lifetime secret is violated. In this paper, we…

基因组学 · 定量生物学 2018-11-28 Ali Gholami , Mohammad Ali Maddah-Ali , Seyed Abolfazl Motahari

Genome sequencing technology has advanced at a rapid pace and it is now possible to generate highly-detailed genotypes inexpensively. The collection and analysis of such data has the potential to support various applications, including…

The DNA sequencing is the process of identifying the exact order of nucleotides within a given DNA molecule. The new portable and relatively inexpensive DNA sequencers, such as Oxford Nanopore MinION, have the potential to move DNA…

计算工程、金融与科学 · 计算机科学 2019-01-09 Steven Y. Ko , Lauren Sassoubre , Jaroslaw Zola

Recent advances in DNA sequencing technologies have put ubiquitous availability of fully sequenced human genomes within reach. It is no longer hard to imagine the day when everyone will have the means to obtain and store one's own DNA…

密码学与安全 · 计算机科学 2015-03-19 Pierre Baldi , Roberta Baronio , Emiliano De Cristofaro , Paolo Gasti , Gene Tsudik

The cost of DNA sequencing has resulted in a surge of genetic data being utilised to improve scientific research, clinical procedures, and healthcare delivery in recent years. Since the human genome can uniquely identify an individual, this…

密码学与安全 · 计算机科学 2022-02-11 Sara Jafarbeiki , Raj Gaire , Amin Sakzad , Shabnam Kasra Kermanshahi , Ron Steinfeld

DNA sequencing has faced a huge demand since it was first introduced as a service to the public. This service is often offloaded to the sequencing companies who will have access to full knowledge of individuals' sequences, a major violation…

信息论 · 计算机科学 2019-04-04 Ali Gholami , Mohammad Ali Maddah-Ali , Seyed Abolfazl Motahari

Over the past several years, DNA sequencing has emerged as one of the driving forces in life-sciences, paving the way for affordable and accurate whole genome sequencing. As genomes represent the entirety of an organism's hereditary…

密码学与安全 · 计算机科学 2015-02-17 Emiliano De Cristofaro

Rapid advances in human genomics are enabling researchers to gain a better understanding of the role of the genome in our health and well-being, stimulating hope for more effective and cost efficient healthcare. However, this also prompts a…

密码学与安全 · 计算机科学 2018-08-20 Alexandros Mittos , Bradley Malin , Emiliano De Cristofaro

DNA sequencing is revolutionising the field of medicine. DNA sequencers, the machines which perform DNA sequencing, have evolved from the size of a fridge to that of a mobile phone over the last two decades. The cost of sequencing a human…

基因组学 · 定量生物学 2021-01-14 Hasindu Gamaarachchi

The number of smartphones, tablets, sensors, and connected wearable devices are rapidly increasing. Today, in many parts of the globe, the penetration of mobile computers has overtaken the number of traditional personal computers. This…

密码学与安全 · 计算机科学 2014-10-21 Muhammad Haris , Hamed Haddadi , Pan Hui

Sharing genome data in a privacy-preserving way stands as a major bottleneck in front of the scientific progress promised by the big data era in genomics. A community-driven protocol named genomic data-sharing beacon protocol has been…

密码学与安全 · 计算机科学 2020-08-25 Kerem Ayoz , Erman Ayday , A. Ercument Cicek

We show that in device independent quantum key distribution protocols the privacy of randomness is of crucial importance. For sublinear test sample sizes even the slightest guessing probability by an eavesdropper will completely compromise…

量子物理 · 物理学 2013-09-12 Marcus Huber , Marcin Pawlowski

Sequential data is everywhere, and it can serve as a basis for research that will lead to improved processes. For example, road infrastructure can be improved by identifying bottlenecks in GPS data, or early diagnosis can be improved by…

密码学与安全 · 计算机科学 2020-02-25 Sigal Shaked , Lior Rokach

In recent years, Whole Genome Sequencing (WGS) evolved from a futuristic-sounding research project to an increasingly affordable technology for determining complete genome sequences of complex organisms, including humans. This prompts a…

密码学与安全 · 计算机科学 2015-02-17 Erman Ayday , Emiliano De Cristofaro , Jean-Pierre Hubaux , Gene Tsudik

When an individual's DNA is sequenced, sensitive medical information becomes available to the sequencing laboratory. A recently proposed way to hide an individual's genetic information is to mix in DNA samples of other individuals. We…

信息论 · 计算机科学 2024-11-05 Kayvon Mazooji , Roy Dong , Ilan Shomorony

Large genomic datasets are now created through numerous activities, including recreational genealogical investigations, biomedical research, and clinical care. At the same time, genomic data has become valuable for reuse beyond their…

密码学与安全 · 计算机科学 2021-12-28 Rajagopal Venkatesaramani , Zhiyu Wan , Bradley A. Malin , Yevgeniy Vorobeychik

DNA sequencing is becoming increasingly commonplace, both in medical and direct-to-consumer settings. To promote discovery, collected genomic data is often de-identified and shared, either in public repositories, such as OpenSNP, or with…

机器学习 · 计算机科学 2022-12-21 Rajagopal Venkatesaramani , Bradley A. Malin , Yevgeniy Vorobeychik

Nanopore sequencing technology has the potential to render other sequencing technologies obsolete with its ability to generate long reads and provide portability. However, high error rates of the technology pose a challenge while generating…

基因组学 · 定量生物学 2019-12-20 Damla Senol Cali , Jeremie S. Kim , Saugata Ghose , Can Alkan , Onur Mutlu

Printing custom DNA sequences is essential to scientific and biomedical research, but the technology can be used to manufacture plagues as well as cures. Just as ink printers recognize and reject attempts to counterfeit money, DNA…

With the continued improvement of sequencing technologies, the prospect of genome-based medicine is now at the forefront of scientific research. To realize this potential, however, we need a revolutionary sequencing method for the…

生物物理 · 物理学 2008-01-03 Michael Zwolak , Massimiliano Di Ventra
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