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We propose a virtual clinical trial for assessing the safety and efficacy of closed-loop diabetes treatments prior to an actual clinical trial. Such virtual trials enable rapid and risk-free pretrial testing of algorithms, and they can be…

最优化与控制 · 数学 2022-05-04 Tobias K. S. Ritschel , Asbjørn Thode Reenberg , John Bagterp Jørgensen

Diabetes mellitus affects over 537 million adults worldwide and remains a major challenge in preventive healthcare. Existing machine-learning studies primarily formulate diabetes prediction as a binary classification problem, while…

机器学习 · 计算机科学 2026-05-14 Vishal Pandey , Ruzina Haque Laskar , Rishav Tewari

Despite recent advances in insulin preparations and technology, adjusting insulin remains an ongoing challenge for the majority of people with type 1 diabetes (T1D) and longstanding type 2 diabetes (T2D). In this study, we propose the…

Type 1 diabetes (T1D) is an autoimmune disorder that leads to the destruction of insulin-producing cells, resulting in insulin deficiency, as to why the affected individuals depend on external insulin injections. However, insulin can…

机器学习 · 计算机科学 2026-04-27 Beyza Cinar , Maria Maleshkova

Research process automation -- the reliable, efficient, and reproducible execution of linked sets of actions on scientific instruments, computers, data stores, and other resources -- has emerged as an essential element of modern science. We…

分布式、并行与集群计算 · 计算机科学 2022-12-08 Ryan Chard , Jim Pruyne , Kurt McKee , Josh Bryan , Brigitte Raumann , Rachana Ananthakrishnan , Kyle Chard , Ian Foster

This paper presents ZeloS, a research platform designed and built for practical validation of automated driving methods in an early stage of research. We overview ZeloS' hardware setup and automation architecture and focus on motion…

Type 2 Diabetes is a fast-growing, chronic metabolic disorder due to imbalanced insulin activity.The motion of this research is a comparative study of seven machine learning classifiers and an artificial neural network method to…

机器学习 · 计算机科学 2023-01-10 Md. Kowsher , Mahbuba Yesmin Turaba , Tanvir Sajed , M M Mahabubur Rahman

This paper presents the Accurate Google Cloud Simulator (AGOCS) - a novel high-fidelity Cloud workload simulator based on parsing real workload traces, which can be conveniently used on a desktop machine for day-to-day research. Our…

分布式、并行与集群计算 · 计算机科学 2025-10-01 Leszek Sliwko , Vladimir Getov

Diabetes is a chronic metabolic disorder characterized by persistently high blood glucose levels (BGLs), leading to severe complications such as cardiovascular disease, neuropathy, and retinopathy. Predicting BGLs enables patients to…

We present a method to estimate parameters in pharmacokinetic (PK) and pharmacodynamic (PD) models for glucose insulin dynamics in humans. The method combines 1) experimental glucose infusion rate (GIR) data from glucose clamp studies and…

This paper presents a novel approach to noninvasive hyperglycemia monitoring utilizing electrocardiograms (ECG) from an extensive database comprising 1119 subjects. Previous research on hyperglycemia or glucose detection using ECG has been…

信号处理 · 电气工程与系统科学 2024-03-13 MohammadReza Hosseinzadehketilateh , Banafsheh Adami , Nima Karimian

Optical continuous glucose monitoring (CGM) systems are emerging for personalized glucose management owing to their lower cost and prolonged durability compared to conventional electrochemical CGMs. Here, we report a computational CGM…

People with diabetes have to manage their blood glucose level to keep it within an appropriate range. Predicting whether future glucose values will be outside the healthy threshold is of vital importance in order to take corrective actions…

机器学习 · 计算机科学 2023-04-03 J. Alvarado , J. Manuel Velasco , F. Chávez , J. Ignacio Hidalgo , F. Fernández de Vega

Progress in Type 1 Diabetes (T1D) algorithm development is limited by the fragmentation and lack of standardization across existing T1D management datasets. Current datasets differ substantially in structure and are time-consuming to access…

机器学习 · 计算机科学 2026-04-23 Miriam K. Wolff , Peter Calhoun , Eleonora Maria Aiello , Yao Qin , Sam F. Royston

The availability of continuous glucose monitors as over-the-counter commodities have created a unique opportunity to monitor a person's blood glucose levels, forecast blood glucose trajectories and provide automated interventions to prevent…

机器学习 · 计算机科学 2026-04-16 Ebrahim Farahmand , Shovito Barua Soumma , Nooshin Taheri Chatrudi , Hassan Ghasemzadeh

Objective: The artificial pancreas (AP) has shown promising potential in achieving closed-loop glucose control for individuals with type 1 diabetes mellitus (T1DM). However, designing an effective control policy for the AP remains…

人工智能 · 计算机科学 2023-07-17 Wenzhou Lv , Tianyu Wu , Luolin Xiong , Liang Wu , Jian Zhou , Yang Tang , Feng Qian

Diabetes mellitus is a common disease of human body caused by a group of metabolic disorders where the sugar levels over a prolonged period is very high. It affects different organs of the human body which thus harm a large number of the…

机器学习 · 计算机科学 2019-02-27 Md. Faisal Faruque , Asaduzzaman , Iqbal H. Sarker

Accurate long-horizon glucose forecasting is critical for automated insulin delivery systems, which help people with type 1 diabetes (T1D) manage their glucose and avoid dangerous hypoglycemia. However, standard recursive long short-term…

机器学习 · 计算机科学 2026-05-19 Phat Tran , Neville Mehta , Clara Mosquera-Lopez , Robert H. Dodier , Lizhong Chen , Peter G. Jacobs

This systematic review explores the use of machine learning (ML) in predicting diabetes, focusing on datasets, algorithms, training methods, and evaluation metrics. It examines datasets like the Singapore National Diabetic Retinopathy…

软件工程 · 计算机科学 2026-04-30 Pir Bakhsh Khokhar , Carmine Gravino , Fabio Palomba

Algorithm Operating System (AlgOS) is an unopinionated, extensible, modular framework for algorithmic implementations. AlgOS offers numerous features: integration with Optuna for automated hyperparameter tuning; automated argument parsing…

软件工程 · 计算机科学 2025-04-08 Llewyn Salt , Marcus Gallagher
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