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Type 2 diabetes progresses slowly and may be reversed through lifestyle changes, but quantifying the long-term impact of regular physical activity remains challenging due to sparse longitudinal data. Mechanistic models offer a powerful tool…

The role played by physical activity in slowing down the progression of type-2 diabetes is well recognized. However, except for general clinical guidelines, quantitative real-time estimates of the recommended amount of physical activity,…

系统与控制 · 电气工程与系统科学 2025-03-13 Pierluigi Francesco De Paola , Alessandro Borri , Alessia Paglialonga , Pasquale Palumbo , Fabrizio Dabbene

Large clinical evidence acknowledges the crucial role played by physical activity in delaying the progression of type-2 diabetes. However, the literature lacks control approaches that leverage exercise for type-2 diabetes control and more…

系统与控制 · 电气工程与系统科学 2025-01-23 Pierluigi Francesco De Paola , Alessandro Borri , Fabrizio Dabbene , Pasquale Palumbo , Alessia Paglialonga

The goal of this paper is to propose a new mathematical model for the combined effect of different treatments and lifestyles on the glucose-insulin dynamics of Type 2 diabetes (T2D) patients. The model gives the possibility to take into…

系统与控制 · 电气工程与系统科学 2023-01-11 Mohamad Al Ahdab , John Leth , Torben Knudsen , Peter Vestergaard , Henrik Clausen

In this paper, models of the blood glucose (BG) dynamics in people with Type 1 diabetes (T1D) in response to moderate intensity aerobic activity are derived from physiology-based first principles and system identification experiments. We…

系统与控制 · 电气工程与系统科学 2023-07-18 Mehrad Jaloli , Marzia Cescon

With the increasing availability of wearable devices, continuous monitoring of individuals' physiological and behavioral patterns has become significantly more accessible. Access to these continuous patterns about individuals' statuses…

We propose and create an incentive based recommendation algorithm aimed at improving the lifestyle of diabetic patients. This algorithm is integrated into a real world mobile application to provide personalized health recommendations.…

人机交互 · 计算机科学 2025-04-22 Wasim Abbas , Hafiz Syed Muhammad Bilal , Asim Abbas , Muhammad Afzal , Je-Hoon Lee

Type 2 diabetes mellitus (T2DM) is a chronic disease that often results in multiple complications. Risk prediction and profiling of T2DM complications is critical for healthcare professionals to design personalized treatment plans for…

机器学习 · 计算机科学 2019-04-03 Bin Liu , Ying Li , Soumya Ghosh , Zhaonan Sun , Kenney Ng , Jianying Hu

We develop a new model of insulin-glucose dynamics for forecasting blood glucose in type 1 diabetics. We augment an existing biomedical model by introducing time-varying dynamics driven by a machine learning sequence model. Our model…

机器学习 · 统计学 2020-08-10 Andrew C. Miller , Nicholas J. Foti , Emily Fox

Objective: Numerous glucose prediction algorithm have been proposed to empower type 1 diabetes (T1D) management. Most of these algorithms only account for input such as glucose, insulin and carbohydrate, which limits their performance.…

组织与器官 · 定量生物学 2024-12-20 Chengyuan Liu , Josep Vehi , Nick Oliver , Pantelis Georgiou , Pau Herrero

The global prevalence of diabetes, particularly type 2 diabetes mellitus (T2DM), is rapidly increasing, posing significant health and economic challenges. T2DM not only disrupts blood glucose regulation but also damages vital organs such as…

机器学习 · 计算机科学 2025-06-09 Praveen Kumar , Vincent T. Metzger , Scott A. Malec

Regular physical activity is known to be beneficial to people suffering from diabetes type 2. Nevertheless, most such people are sedentary. Smartphones create new possibilities for helping people to adhere to their physical activity goals,…

计算机与社会 · 计算机科学 2018-05-16 Irit Hochberg , Guy Feraru , Mark Kozdoba , Shie Mannor , Moshe Tennenholtz , Elad Yom-Tov

Diabetes is a chronic metabolic disorder characterized by elevated blood glucose levels due to impaired insulin production or function. Two main forms are recognized: type 1 diabetes (T1D), which involves autoimmune destruction of…

基因组学 · 定量生物学 2026-02-11 Maria De La Luz Lomboy Toledo , Daniel Onah

Type 1 Diabetes (T1D) affects millions worldwide, requiring continuous monitoring to prevent severe hypo- and hyperglycemic events. While continuous glucose monitoring has improved blood glucose management, deploying predictive models on…

机器学习 · 计算机科学 2025-11-27 Mirko Paolo Barbato , Giorgia Rigamonti , Davide Marelli , Paolo Napoletano

Diabetes affects over 400 million people and is among the leading causes of morbidity worldwide. Identification of high-risk individuals can support early diagnosis and prevention of disease development through lifestyle changes. However,…

Diabetes cases worldwide have risen steadily over the past decades, lending urgency to the search for more efficient, effective, and personalized ways to treat the disease. Current treatment strategies, however, may fail to maintain…

组织与器官 · 定量生物学 2014-03-05 S. M. Kissler , C. Cichowitz , S. Sankaranarayanan , D. M. Bortz

Early diagnosis is important for type 2 diabetes (T2D) to improve patient prognosis, prevent complications and reduce long-term treatment costs. We present a novel risk profiling approach based exclusively on health expenditure data that is…

机器学习 · 统计学 2015-04-29 Marc Claesen , Frank De Smet , Pieter Gillard , Chantal Mathieu , Bart De Moor

Type 2 Diabetes is a fast-growing, chronic metabolic disorder due to imbalanced insulin activity.The motion of this research is a comparative study of seven machine learning classifiers and an artificial neural network method to…

机器学习 · 计算机科学 2023-01-10 Md. Kowsher , Mahbuba Yesmin Turaba , Tanvir Sajed , M M Mahabubur Rahman

Nonlinear mixed effects models represent a powerful tool to simultaneously analyze data from several individuals. In this study a compartmental model of leucine kinetics is examined and extended with a stochastic differential equation to…

定量方法 · 定量生物学 2011-01-05 Martin Berglund , Mikael Sunnåker , Martin Adiels , Mats Jirstrand , Bernt Wennberg

We describe a strategy for the acquisition of training data necessary to build a social-media-driven early detection system for individuals at risk for (preventable) type 2 diabetes mellitus (T2DM). The strategy uses a game-like quiz with…

计算与语言 · 计算机科学 2016-03-15 Dane Bell , Daniel Fried , Luwen Huangfu , Mihai Surdeanu , Stephen Kobourov
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