相关论文: Analytical Characterization of Epileptic Dynamics …

This paper analyses the stability of cycles within a heteroclinic network lying in a three-dimensional manifold formed by six cycles, for a one-parameter model developed in the context of game theory. We show the asymptotic stability of the…

We study how the connectivity within a recurrent neural network determines and is determined by the multistable solutions of network activity. To gain analytic tractability we let neural activation be a non-smooth Heaviside step function.…

Neural mass models are used to simulate cortical dynamics and to explain the electrical and magnetic fields measured using electro- and magnetoencephalography. Simulations evince a complex phase-space structure for these kinds of models;…

We explore sequential escape behaviour of coupled bistable systems under the influence of stochastic perturbations. We consider transient escapes from a marginally stable "quiescent" equilibrium to a more stable "active" equilibrium. The…

Interictal spikes and sharp waves in human EEG are characteristic signatures of epilepsy. These potentials originate as a result of synchronous, pathological discharge of many neurons. The reliable detection of such potentials has been the…

Epilepsy represents the most prevalent neurological disease in the world. One-third of people suffering from mesial temporal lobe epilepsy (MTLE) exhibit drug resistance, urging the need to develop new treatments. A key part in anti-seizure…

Hysteresis dynamics has been described in a vast number of biological experimental studies. Many such studies are phenomenological and a mathematical appreciation has not attracted enough attention. In the paper, we explore the nature of…

Chimera states---the coexistence of synchrony and asynchrony in a nonlocally-coupled network of identical oscillators---are often used as a model framework for epileptic seizures. Here, we explore the dynamics of chimera states in a network…

Inhibitory neurons play a crucial role in maintaining persistent neuronal activity. Although connected extensively through electrical synapses (gap-junctions), these neurons also exhibit interactions through chemical synapses in certain…

In neural circuits, synaptic strengths influence neuronal activity by shaping network dynamics, and neuronal activity influences synaptic strengths through activity-dependent plasticity. Motivated by this fact, we study a recurrent-network…

We study two-dimensional triangular-network models, which have degenerate ground states composed of straight or randomly-zigzagging stripes and thus sub-extensive residual entropy. We show that attraction is responsible for the inversion of…

Chimera states and bump states are collective synchronization phenomena observed independently (at different parameter regions) in networks of coupled nonlinear oscillators. And while chimera states are characterized by coexistence of…

This paper presents a method that learns a regionally stable recurrent neural network model from a set of input-output data generated by an unknown dynamical system. Relying on generalized sector conditions on the deadzone activation…

Epilepsy is one of the most serious neurological diseases, affecting 1-2% of the world's population. The diagnosis of epilepsy depends heavily on the recognition of epileptic waves, i.e., disordered electrical brainwave activity in the…

We studied autoassociative networks in which synapses are noisy on a time scale much shorter that the one for the neuron dynamics. In our model a presynaptic noise causes postsynaptic depression as recently observed in neurobiological…

The analysis of noise-induced escape in populations of bistable elements is challenging, because nonlinearity, coupling, and noise all play essential roles. We show that the interplay of these three factors yields three qualitatively…

Spontaneous cortical population activity exhibits a multitude of oscillatory patterns, which often display synchrony during slow-wave sleep or under certain anesthetics and stay asynchronous during quiet wakefulness. The mechanisms behind…

Cortical neurons are bistable; as a consequence their local field potentials can fluctuate between quiescent and active states, generating slow 0.5-2 Hz oscillations which are widely known as transitions between Up and Down States. Despite…

We investigate an epidemiological model that incorporates waning of immunity at the individual level and boosting of the immune system upon re-exposure to the pathogen. When immunity is fully restored upon boosting, the system can be…

The brain is a high-dimensional directional network system consisting of many regions as network nodes that influence each other. The directional influence from one region to another is referred to as directional connectivity. Epilepsy is a…