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Nonlinear Noisy Leaky Integrate and Fire (NNLIF) models for neurons networks can be written as Fokker-Planck-Kolmogorov equations on the probability density of neurons, the main parameters in the model being the connectivity of the network…

神经元与认知 · 定量生物学 2010-10-25 María J. Cáceres , José A. Carrillo , Benoît Perthame

Neural network dynamics emerge from the interaction of spiking cells. One way to formulate the problem is through a theoretical framework inspired by ideas coming from statistical physics, the so-called mean-field theory. In this document,…

偏微分方程分析 · 数学 2020-11-11 Grégory Dumont , Pierre Gabriel

Neurons and networks in the cerebral cortex must operate reliably despite multiple sources of noise. To evaluate the impact of both input and output noise, we determine the robustness of single-neuron stimulus selective responses, as well…

神经元与认知 · 定量生物学 2018-01-24 Ran Rubin , L. F. Abbott , Haim Sompolinsky

Excessively high, neural synchronisation has been associated with epileptic seizures, one of the most common brain diseases worldwide. A better understanding of neural synchronisation mechanisms can thus help control or even treat epilepsy.…

This paper introduces a class of stochastic models of interacting neurons with emergent dynamics similar to those seen in local cortical populations, and compares them to very simple reduced models driven by the same mean excitatory and…

神经元与认知 · 定量生物学 2017-11-07 Yao Li , Logan Chariker , Lai-Sang Young

Providing an analytical treatment to the stochastic feature of neurons' dynamics is one of the current biggest challenges in mathematical biology. The noisy leaky integrate-and-fire model and its associated Fokker-Planck equation are…

神经元与认知 · 定量生物学 2015-12-14 Grégory Dumont , Jacques Henry , Carmen Oana Tarniceriu

We study temporal correlations of interspike intervals (ISIs), quantified by the network-averaged serial correlation coefficient (SCC), in networks of both current- and conductance-based purely inhibitory integrate-and-fire neurons.…

神经元与认知 · 定量生物学 2019-03-27 Wilhelm Braun , André Longtin

We continue the work of a series of previous studies of a mathematical model that describes the mean-field limit behavior of a homogeneous network of excitatory point spiking neurons. Contrary to other models, here noise is intrinsic to the…

神经元与认知 · 定量生物学 2017-07-20 Guillem Via

Noise appears in the brain due to various sources, such as ionic channel fluctuations and synaptic events. They affect the activities of the brain and influence neuron action potentials. Stochastic differential equations have been used to…

The importance of self-feedback autaptic transmission in modulating spike-time irregularity is still poorly understood. By using a biophysical model that incorporates autaptic coupling, we here show that self-innervation of neurons…

神经元与认知 · 定量生物学 2016-07-04 Daqing Guo , Shengdun Wu , Mingming Chen , Matjaz Perc , Yangsong Zhang , Jingling Ma , Yan Cui , Peng Xu , Yang Xia , Dezhong Yao

A population of firing neurons is expected to carry not only mean firing rate but also its fluctuation and synchrony among neurons. In order to examine this possibility, we have studied responses of neuronal ensembles to three kinds of…

无序系统与神经网络 · 物理学 2008-02-18 Hiode Hasegawa

Reduced models of neuronal activity such as Integrate-and-Fire models allow a description of neuronal dynamics in simple, intuitive terms and are easy to simulate numerically. We present a method to fit an Integrate-and-Fire-type model of…

神经元与认知 · 定量生物学 2020-04-03 Renaud Jolivet , Wulfram Gerstner

Strong inhibitory input to neurons, which occurs in balanced states of neural networks, increases synaptic current fluctuations. This has led to the assumption that inhibition contributes to the high spike-firing irregularity observed in…

神经元与认知 · 定量生物学 2021-02-19 Tomas Barta , Lubomir Kostal

Activity of inhibitory neuron with delayed feedback is considered in the framework of point stochastic processes. The neuron receives excitatory input impulses from a Poisson stream, and inhibitory impulses from the feedback line with a…

神经元与认知 · 定量生物学 2013-09-10 Alexander K. Vidybida , Kseniya G. Kravchuk

Excitatory and inhibitory nonlinear noisy leaky integrate and fire models are often used to describe neural networks. Recently, new mathematical results have provided a better understanding of them. It has been proved that a fully…

偏微分方程分析 · 数学 2016-09-07 María J. Cáceres , Ricarda Schneider

Cortical neurons are characterized by irregular firing and a broad distribution of rates. The balanced state model explains these observations with a cancellation of mean excitatory and inhibitory currents, which makes fluctuations drive…

神经元与认知 · 定量生物学 2020-10-15 Alessandro Sanzeni , Mark H Histed , Nicolas Brunel

We study analytically the dynamics of a network of sparsely connected inhibitory integrate-and-fire neurons in a regime where individual neurons emit spikes irregularly and at a low rate. In the limit when the number of neurons N tends to…

无序系统与神经网络 · 物理学 2007-05-23 N. Brunel , V. Hakim

We review the use of mean field theory for describing the dynamics of dense, randomly connected cortical circuits. For a simple network of excitatory and inhibitory leaky integrate-and-fire neurons, we can show how the firing irregularity,…

神经元与认知 · 定量生物学 2007-05-23 John Hertz , Alexander Lerchner , Mandana Ahmadi

We study a system of perfect integrate-and-fire inhibitory neurons. It is a system of stochastic processes which interact through receiving an instantaneous increase at the moments they reach certain thresholds. In the absence of…

概率论 · 数学 2018-09-25 Timofei Prasolov

Variability in neural responses is an ubiquitous phenomenon in neurons, usually modeled with stochastic differential equations. In particular, stochastic integrate-and-fire models are widely used to simplify theoretical studies. The…

神经元与认知 · 定量生物学 2009-06-12 Eugenio Urdapilleta , Ines Samengo