相关论文: On a mathematical model for tissue regeneration

We study a model for the spread and (de)differentiation of mesenchymal stem cells and chondrocytes in a scaffold whose fibers are coated with hyaluron. The chondrocytes produce new extracellular matrix, which, together with hyaluron, serves…

We provide a short review of existing models with multiple taxis performed by (at least) one species and consider a new mathematical model for tumor invasion featuring two mutually exclusive cell phenotypes (migrating and proliferating).…

In this paper we focus on learning optimized partial differential equation (PDE) models for image filtering. In this approach, the grey-scaled images are represented by a vector field of two real-valued functions and the image restoration…

In this work we analyse a PDE-ODE problem modelling the evolution of a Glioblastoma, which includes chemotaxis term directed to vasculature. First, we obtain some a priori estimates for the (possible) solutions of the model. In particular,…

Motivated by an ongoing collaboration with clinical oncologists and pathologists, we develop a hybrid partial differential equation--ordinary differential equation (PDE--ODE) framework that captures (i) competition between susceptible and…

We study a PDE model for dynamics of susceptible-infected interactions. The dispersal of susceptibles is via diffusion and repellent taxis as they move away from the increasing density of infected. The diffusion of infected is a nonlinear,…

We propose a simple model for scaffold aided bone regeneration. In this model, only macroscopic quantities, e.g., locally averaged osteoblast densities, are considered. This allows for use of this model in an optimization algorithm, whose…

The transport of intensity equation (TIE) has revolutionized phase retrieval in optical microscopy, yet its application to complex media with absorption/scattering remains challenging. Here, we present a coupled TIE-TPE (transport of phase…

We propose a novel approach to modeling cell migration in an anisotropic environment with biochemical heterogeneity and interspecies interactions, using as a paradigm glioma invasion in brain tissue under the influence of hypoxia-triggered…

In this paper we establish a homogenization result for a doubly nonlinear parabolic system arising from the hygro-thermo-chemical processes in porous media taking into account memory phenomena. We present a meso-scale model of the composite…

We introduce a new diffuse interface model for tumour growth in the presence of a nutrient, in which we take into account mechanical effects and reversible tissue damage. The highly nonlinear PDEs system mainly consists of a Cahn-Hilliard…

We consider a model for the dynamics of active cells interacting with their quiescent counterparts under the influence of acidity characterized by proton concentration. The active cells perform nonlinear diffusion and infer proliferation or…

In this work, we introduce a novel first-order nonlocal partial differential equation with saturated diffusion to describe the macroscopic behavior of traffic dynamics. We show how the proposed model is better in comparison with existing…

We analyze a class of cell-bulk coupled PDE-ODE models, motivated by quorum and diffusion sensing phenomena in microbial systems, that characterize communication between localized spatially segregated dynamically active signaling…

Tissue engineering aims to grow artificial tissues \emph{in vitro} to replace those in the body that have been damaged through age, trauma or disease. A recent approach to engineer artificial cartilage involves seeding cells within a…

The aim of the present paper is to efficiently describe the membrane potential dynamics of neural populations formed by species having a high density difference in specific brain areas. We propose a hybrid model whose main ingredients are a…

Two-scale models pose a promising approach in simulating reactive flow and transport in evolving porous media. Classically, homogenized flow and transport equations are solved on the macroscopic scale, while effective parameters are…

We study an elliptic-parabolic system of partial differential equations describing formation of biological network structures. The model takes into consideration the evolution of the permeability tensor under the influence of a diffusion…

It has been shown experimentally that contact interactions may influence the migration of cancer cells. Previous works have modelized this thanks to stochastic, discrete models (cellular automata) at the cell level. However, for the study…

Developing clinically viable tissue-engineered cardiovascular implants remains a formidable challenge. Achieving reliable and durable outcomes requires a deeper understanding of the fundamental mechanisms driving tissue evolution during in…