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In many practical situations, randomly assigning treatments to subjects is uncommon due to feasibility constraints. For example, economic aid programs and merit-based scholarships are often restricted to those meeting specific income or…

统计方法学 · 统计学 2025-04-25 Kevin Christian Wibisono , Debarghya Mukherjee , Moulinath Banerjee , Ya'acov Ritov

Matrix regression plays an important role in modern data analysis due to its ability to handle complex relationships involving both matrix and vector variables. We propose a class of regularized regression models capable of predicting both…

最优化与控制 · 数学 2025-01-14 Meixia Lin , Ziyang Zeng , Yangjing Zhang

A popular technique for selecting and tuning machine learning estimators is cross-validation. Cross-validation evaluates overall model fit, usually in terms of predictive accuracy. In causal inference, the optimal choice of estimator…

统计方法学 · 统计学 2021-07-07 Dominik Rothenhäusler

Double Machine Learning is widely used to estimate causal treatment effects in large-scale observational data. The ``residuals-on-residuals'' regression estimator (RORR) is especially popular for its simplicity and computational…

计量经济学 · 经济学 2025-11-27 Apoorva Lal , Winston Chou

Kernel matching is a widely used technique for estimating treatment effects, particularly valuable in observational studies where randomized controlled trials are not feasible. While kernel-matching approaches have demonstrated practical…

统计方法学 · 统计学 2025-12-11 Chong Ding , Zheng Li , Hon Keung Tony Ng , Wei Gao

Platform trials are multi-arm designs that simultaneously evaluate multiple treatments for a single disease within the same overall trial structure. Unlike traditional randomized controlled trials, they allow treatment arms to enter and…

统计方法学 · 统计学 2024-12-16 Michele Santacatterina , Federico Macchiavelli Giron , Xinyi Zhang , Ivan Diaz

Incrementality experiments compare customers exposed to a marketing action designed to increase sales to those randomly assigned to a control group. These experiments suffer from noisy responses which make precise estimation of the average…

应用统计 · 统计学 2023-05-11 Ron Berman , Elea McDonnell Feit

Randomized experiments (a.k.a. A/B tests) are a powerful tool for estimating treatment effects, to inform decisions making in business, healthcare and other applications. In many problems, the treatment has a lasting effect that evolves…

机器学习 · 计算机科学 2022-10-17 Ziyang Tang , Yiheng Duan , Stephanie Zhang , Lihong Li

Mixed Models for Repeated Measures (MMRMs) are ubiquitous when analyzing outcomes of clinical trials. However, the linearity of the fixed-effect structure in these models largely restrict their use to estimating treatment effects that are…

统计方法学 · 统计学 2023-01-23 Lars Lau Raket

Estimating heterogeneous treatment effect (HTE) for survival outcomes has gained increasing attention, as it captures the variation in treatment efficacy across patients or subgroups in delaying disease progression. However, most existing…

统计方法学 · 统计学 2025-11-27 Na Bo , Ying Ding

Target trial emulation (TTE) enables causal questions to be studied with observational data when randomized controlled trials (RCTs) are infeasible. Yet treatment-effect methods often address causal estimation, missingness, and temporal…

When evaluating a two-phase intervention, the cumulative average treatment effect (ATE) is often the primary causal estimand of interest. However, some individuals who do not respond well to the Phase I treatment may subsequently display…

统计方法学 · 统计学 2026-02-02 Guanglei Hong , Xu Qin , Zhengyan Xu , Fan Yang

This note extends a recently proposed algorithm for model identification and robust MPC of asymptotically stable, linear time-invariant systems subject to process and measurement disturbances. Independent output predictors for different…

系统与控制 · 电气工程与系统科学 2021-03-02 Enrico Terzi , Lorenzo Fagiano , Marcello Farina , Riccardo Scattolini

Recently, many researchers have advanced data-driven methods for modeling heterogeneous treatment effects (HTEs). Even still, estimation of HTEs is a difficult task -- these methods frequently over- or under-estimate the treatment effects,…

统计方法学 · 统计学 2022-03-28 Yizhe Xu , Steve Yadlowsky

When treatment effects are naturally expressed as ratios -- as in medicine, pricing, and marketing -- the ratio-based CATE $\tau(x) = E[Y|W=1,X=x] / E[Y|W=0,X=x]$ is the appropriate estimand. Yet existing estimators either impose a…

机器学习 · 统计学 2026-05-27 Michael Fuchs , Dominik Kreiss

We consider inference about a scalar parameter under a non-parametric model based on a one-step estimator computed as a plug in estimator plus the empirical mean of an estimator of the parameter's influence function. We focus on a class of…

统计理论 · 数学 2019-06-07 Ezequiel Smucler , Andrea Rotnitzky , James M. Robins

There is a growing interest in studying sequential neural posterior estimation (SNPE) techniques due to their advantages for simulation-based models with intractable likelihoods. The methods aim to learn the posterior from adaptively…

统计计算 · 统计学 2025-10-16 Xiliang Yang , Yifei Xiong , Zhijian He

We introduce mixed model trace regression (MMTR), a mixed model linear regression extension for scalar responses and high-dimensional matrix-valued covariates. MMTR's fixed effects component is equivalent to trace regression, with an…

统计方法学 · 统计学 2025-03-19 Ian Hultman , Sanvesh Srivastava

In this paper, we mainly focus on the penalized maximum likelihood estimation (MLE) of the high-dimensional approximate factor model. Since the current estimation procedure can not guarantee the positive definiteness of the error covariance…

统计计算 · 统计学 2019-01-18 Shaoxin Wang , Hu Yang , Chaoli Yao

Methods for estimating heterogeneous treatment effect in observational data have largely focused on continuous or binary outcomes, and have been relatively less vetted with survival outcomes. Using flexible machine learning methods in the…

应用统计 · 统计学 2021-07-09 Liangyuan Hu , Jiayi Ji , Fan Li