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Genetic Programming yields interpretable programs, but small syntactic mutations can induce large, unpredictable behavioral shifts, degrading locality and sample efficiency. We frame this as an operator-design problem: learn a continuous…

机器学习 · 计算机科学 2026-02-10 Matthew Siper , Muhammad Umair Nasir , Ahmed Khalifa , Lisa Soros , Jay Azhang , Julian Togelius

Motivation: Most existing methods for DNA sequence analysis rely on accurate sequences or genotypes. However, in applications of the next-generation sequencing (NGS), accurate genotypes may not be easily obtained (e.g. multi-sample…

基因组学 · 定量生物学 2013-03-19 Heng Li

This paper studies the recovery of a superposition of point sources from noisy bandlimited data. In the fewest possible words, we only have information about the spectrum of an object in a low-frequency band bounded by a certain cut-off…

信息论 · 计算机科学 2013-07-11 Emmanuel Candes , Carlos Fernandez-Granda

We analyze a size-structured branching process in which individual cells grow exponentially according to a Feller square-root process and divide under general size-control mechanisms. We obtain exact expressions for the asymptotic…

种群与进化 · 定量生物学 2025-12-08 Farshid Jafarpour

We consider continuous space-time decay-surge population models which are semi- stochastic processes for which deterministically declining populations, bound to fade away, are rein- vigorated at random times by bursts or surges of random…

概率论 · 数学 2021-11-09 Branda Goncalves , Thierry Huillet , Eva Löcherbach

We present a robust method which translates information on the speed of coming down from infinity of a genealogical tree into sampling formulae for the underlying population. We apply these results to population dynamics where the genealogy…

概率论 · 数学 2012-02-01 Julien Berestycki , Nathanael Berestycki , Vlada Limic

Structured population models are a class of general evolution equations which are widely used in the study of biological systems. Many theoretical methods are available for establishing existence and stability of steady states of general…

偏微分方程分析 · 数学 2016-02-24 Inom Mirzaev , David M. Bortz

We investigate joint spectral characteristics of a family of matrices $\mathcal F $, associated with products in the semigroup generated by $\mathcal F$. In the literature, extremal measures such as the well-known joint spectral radius and…

动力系统 · 数学 2026-04-27 Francesco Paolo Maiale , Anastasiia Trofimova , Nicola Guglielmi

Consider a two-type Moran population of size $N$ with selection and mutation, where the selective advantage of the fit individuals is amplified at extreme environmental conditions. Assume selection and mutation are weak with respect to $N$,…

概率论 · 数学 2023-04-26 Fernando Cordero , Grégoire Véchambre

The specific star formation rate (sSFR) is commonly used to describe the level of galaxy star formation (SF) and to select quenched galaxies. However, being a relative measure of the young-to-old population, an ambiguity in its…

星系天体物理 · 物理学 2023-10-19 Samir Salim , Sandro Tacchella , Chandler Osborne , S. M. Faber , Janice C. Lee , Sara L. Ellison

We consider a general class of Markovian models describing the growth in a randomly fluctuating environment of a clonal biological population having several phenotypes related by stochastic switching. Phenotypes differ e.g. by the level of…

种群与进化 · 定量生物学 2022-01-25 J. Unterberger

The spatial structure of an evolving population affects which mutations become fixed. Some structures amplify selection, increasing the likelihood that beneficial mutations become fixed while deleterious mutations do not. Other structures…

It recently has been found that methods of the statistical theories of spectra can be a useful tool in the analysis of spectra far from levels of Hamiltonian systems. Several examples originate from areas, such as quantitative linguistics…

统计力学 · 物理学 2020-05-26 Rongrong Xie , Weibing Deng , Mauricio P. Pato

We consider birth-and-death stochastic evolution of genotypes with different lengths. The genotypes might mutate that provides a stochastic changing of lengthes by a free diffusion law. The birth and death rates are length dependent which…

种群与进化 · 定量生物学 2015-06-16 Dmitri Finkelshtein , Yuri Kondratiev , Oleksandr Kutoviy , Stanislav Molchanov , Elena Zhizhina

We consider the genealogical tree of a stationary continuous state branching process with immigration. For a sub-critical stable branching mechanism, we consider the genealogical tree of the extant population at some fixed time and prove…

概率论 · 数学 2020-05-21 Romain Abraham , Jean-François Delmas , Hui He

We present a model for growth in a multi-species population. We consider two types evolving as a logistic branching process with mutation, where one of the types has a selective advantage, and are interested in the regime in which the…

概率论 · 数学 2025-07-18 Marta Dai Pra , Julian Kern

In this study, we develop consistent estimators for key parameters that govern the dynamics of tumor cell populations when subjected to pharmacological treatments. While these treatments often lead to an initial reduction in the abundance…

应用统计 · 统计学 2024-03-21 Kevin Leder , Ruping Sun , Zicheng Wang , Xuanming Zhang

We present two iterative methods for computing the global and partial extinction probability vectors for Galton-Watson processes with countably infinitely many types. The probabilistic interpretation of these methods involves truncated…

概率论 · 数学 2014-03-06 Sophie Hautphenne , Guy Latouche , Giang Nguyen

Demographic models built from genetic data play important roles in illuminating prehistorical events and serving as null models in genome scans for selection. We introduce an inference method based on the joint frequency spectrum of genetic…

种群与进化 · 定量生物学 2010-05-10 Ryan N. Gutenkunst , Ryan D. Hernandez , Scott H. Williamson , Carlos D. Bustamante

Splicing sites provide unique statistics in human genome due to their large number and reasonably complete annotation. Analyses of the cumulative SNPs distribution in splicing sites reveal a few interesting observations. While a degree of…

基因组学 · 定量生物学 2007-05-23 Dmitri Parkhomchuk