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Multiple imputation (MI) is a popular method for handling missing data. Auxiliary variables can be added to the imputation model(s) to improve MI estimates. However, the choice of which auxiliary variables to include in the imputation model…

Incomplete covariate vectors are known to be problematic for estimation and inferences on model parameters, but their impact on prediction performance is less understood. We develop an imputation-free method that builds on a random…

统计方法学 · 统计学 2024-05-31 Matthew J. Heiner , Garritt L. Page , Fernando Andrés Quintana

The focus of this paper is on quantifying the capacity of covariates in devising efficient treatment rules when data from a randomized trial are available. Conventional one-variable-at-a-time subgroup analysis based on statistical…

应用统计 · 统计学 2020-02-04 Mohsen Sadatsafavi , Mohammad Mansournia , Paul Gustafson

In randomized trials, repeated measures of the outcome are routinely collected. The mixed model for repeated measures (MMRM) leverages the information from these repeated outcome measures, and is often used for the primary analysis to…

统计方法学 · 统计学 2023-07-20 Bingkai Wang , Yu Du

Dynamic Treatment Regimes (DTRs) provide a systematic framework for optimizing sequential decision-making in chronic disease management, where therapies must adapt to patients' evolving clinical profiles. Inverse probability weighting (IPW)…

统计方法学 · 统计学 2026-03-26 Chloe Si , David A. Stephens , Erica E. M. Moodie

This study investigates the impact of masking strategies on time series imputation models in healthcare settings. While current approaches predominantly rely on random masking for model evaluation, this practice fails to capture the…

机器学习 · 计算机科学 2025-02-05 Linglong Qian , Yiyuan Yang , Wenjie Du , Jun Wang , Richard Dobsoni , Zina Ibrahim

The Best-Worst Method (BWM) has emerged as a prominent multi-criteria decision-making method for determining the weights of the decision criteria. Among various BWM models, this research focuses on the linear model of the BWM. This model…

最优化与控制 · 数学 2025-06-24 Harshit M. Ratandhara , Mohit Kumar

Missing data is an important problem in machine learning practice. Starting from the premise that imputation methods should preserve the causal structure of the data, we develop a regularization scheme that encourages any baseline…

机器学习 · 计算机科学 2021-11-08 Trent Kyono , Yao Zhang , Alexis Bellot , Mihaela van der Schaar

We aim to create the highest possible quality of treatment-control matches for categorical data in the potential outcomes framework. Matching methods are heavily used in the social sciences due to their interpretability, but most matching…

机器学习 · 统计学 2019-06-11 Yameng Liu , Aw Dieng , Sudeepa Roy , Cynthia Rudin , Alexander Volfovsky

Missing data arises when certain values are not recorded or observed for variables of interest. However, most of the statistical theory assume complete data availability. To address incomplete databases, one approach is to fill the gaps…

统计方法学 · 统计学 2023-08-15 Luis Alejandro Masmela-Caita , Thais Paiva Galletti , Marcos Oliveira Prates

Joint analysis of multi-omic single-cell data across cohorts has significantly enhanced the comprehensive analysis of cellular processes. However, most of the existing approaches for this purpose require access to samples with complete…

机器学习 · 计算机科学 2024-05-21 Marianne Arriola , Weishen Pan , Manqi Zhou , Qiannan Zhang , Chang Su , Fei Wang

We develop new methods to integrate experimental and observational data in causal inference. While randomized controlled trials offer strong internal validity, they are often costly and therefore limited in sample size. Observational data,…

计量经济学 · 经济学 2025-11-04 Xuelin Yang , Licong Lin , Susan Athey , Michael I. Jordan , Guido W. Imbens

We study the problem of conditional predictive inference on multiple outcomes missing at random (MAR) -- or equivalently, under covariate shift. While the weighted conformal prediction offers a tool for inference under covariate shift with…

统计方法学 · 统计学 2025-08-01 Yonghoon Lee , Edgar Dobriban , Eric Tchetgen Tchetgen

To estimate casual treatment effects, we propose a new matching approach based on the reduced covariates obtained from sufficient dimension reduction. Compared to the original covariates and the propensity score, which are commonly used for…

统计方法学 · 统计学 2017-02-03 Wei Luo , Yeying Zhu

Population adjustment methods such as matching-adjusted indirect comparison (MAIC) are increasingly used to compare marginal treatment effects when there are cross-trial differences in effect modifiers and limited patient-level data. MAIC…

统计方法学 · 统计学 2022-12-06 Antonio Remiro-Azócar , Anna Heath , Gianluca Baio

Missing data imputation, where a model is trained on observed data to estimate unobserved values, is a fundamental problem in machine learning. In this paper, we rigorously formulate imputation model learning as a mean-squared error risk…

机器学习 · 统计学 2026-05-14 Luke Shannon , Song Liu , Katarzyna Reluga

Missing values pose a persistent challenge in modern data science. Consequently, there is an ever-growing number of publications introducing new imputation methods in various fields. The present paper attempts to take a step back and…

统计理论 · 数学 2026-01-21 Jeffrey Näf , Erwan Scornet , Julie Josse

Covariate adjustment and methods of incorporating historical data in randomized clinical trials (RCTs) each provide opportunities to increase trial power. We unite these approaches for the analysis of RCTs with binary outcomes based on the…

统计方法学 · 统计学 2022-12-21 Alyssa M. Vanderbeek , Jessica L. Ross , David P. Miller , Alejandro Schuler

Matching on covariates is a well-established framework for estimating causal effects in observational studies. The principal challenge stems from the often high-dimensional structure of the problem. Many methods have been introduced to…

统计方法学 · 统计学 2022-07-12 Florian Gunsilius , Yuliang Xu

The Best-Worst Method (BWM) is a well-known Multi-Criteria Decision-Making (MCDM) method. This article deals with the multiplicative model of BWM. We first formulate an optimization model that is equivalent to the existing multiplicative…

最优化与控制 · 数学 2025-01-29 Harshit Ratandhara , Mohit Kumar