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We propose a Zernike phase contrast electron microscope that uses an intense laser focus to convert a phase image into a visible image. We present the relativistic quantum theory of the phase shift caused by the laser-electron-interaction,…

仪器与探测器 · 物理学 2010-09-10 Holger Mueller , Jian Jin , Radostin Danev , John Spence , Howard Padmore , Robert M. Glaeser

Low image contrast is a major limitation in transmission electron microscopy, since samples with low atomic number only weakly phase-modulate the illuminating electron beam, and beam-induced sample damage limits the usable electron dose.…

仪器与探测器 · 物理学 2024-03-19 Jeremy J. Axelrod

Manipulating free-space electron wave functions with laser fields can bring about new electron-optical elements for transmission electron microscopy. In particular, a Zernike phase plate would enable high-contrast imaging of soft matter,…

Although defocus can be used to generate partial phase contrast in transmission electron microscope images, cryo-electron microscopy (cryo-EM) can be further improved by the development of phase plates which increase contrast by applying a…

定量方法 · 定量生物学 2024-03-14 Jeremy J. Axelrod , Jessie T. Zhang , Petar N. Petrov , Robert M. Glaeser , Holger Mueller

A new generation of microfabricated MEMS for electron optics is changing electron microscopy for the better. These devices allow operations on the electron beam that are impossible with conventional electron optics. Unprecedented phase…

The secular dynamics of a non-relativistic charged particle in an electromagnetic wave can be described by the ponderomotive potential. Although ponderomotive electron-laser interactions at relativistic velocities are important for emerging…

First results on the experimental realisation of a 2x2 programmable phase plate for electrons are presented. The design consists of an array of electrostatic einzel lenses that influence the phase of electron waves passing through 4…

Electron beams can acquire designed phase modulations by passing through nanostructured material phase plates. These phase modulations enable electron wavefront shaping and benefit electron microscopy, spectroscopy, lithography, and…

应用物理 · 物理学 2020-07-07 Yujia Yang , Chung-Soo Kim , Richard G. Hobbs , Phillip D. Keathley , Karl K. Berggren

We explore the possibility of applying physical phase plates (PPs) in combination with aberration-corrected transmission electron microscopy. Phase-contrast transfer characteristics are calculated and compared for a thin-film based Zernike…

仪器与探测器 · 物理学 2022-05-10 Simon Hettler , Raul Arenal

We present a 48-element programmable phase plate for coherent electron waves produced by a combination of photolithography and focused ion beam. This brings the highly successful concept of wavefront shaping from light optics into the realm…

仪器与探测器 · 物理学 2023-12-06 Chu-Ping Yu , Francisco Vega Ibáñez , Armand Béché , Johan Verbeeck

In this theoretical study we analyze contrast transfer of weak-phase objects in a transmission electron microscope, which is equipped with an aberration corrector (Cs-corrector) in the imaging lens system and a physical phase plate in the…

材料科学 · 物理学 2010-09-22 B. Gamm , K. Schultheiß , R. R. Schröder , D. Gerthsen

Phase-plate transmission electron microscopy has recently regressed since a report that Volta phase-plate phase-contrast is less sensitive than non-phase-plate phase contrast, which leads to conventional defocusing phase-contrast. What…

光学 · 物理学 2023-07-05 Kuniaki Nagayama

We propose and theoretically demonstrate a technique that allows one to compensate for chromatic aberrations of traditional electron lenses in ultrafast electron microscopes. The technique is based on space- and time-dependent phase…

Current progress in programmable electrostatic phase plates raises questions about their usefulness for specific applications. Here, we explore different designs for such phase plates with the specific goal of correcting spherical…

应用物理 · 物理学 2023-09-28 Francisco Vega Ibáñez , Armand Béché , Johan Verbeeck

For decades since the development of phase-contrast optical microscopy, an analogous approach has been sought for maximizing the image contrast of weakly-scattering objects in transmission electron microscopy (TEM). The recent development…

A novel device that can be used as a tunable support-free phase plate for transmission electron microscopy of weakly scattering specimens is described. The device relies on the generation of a controlled phase shift by the magnetic field of…

Transmission electron microscopy (TEM) of vitrified biological macromolecules (cryo-EM) is limited by the weak phase contrast signal that is available from such samples. Using a phase plate would thus substantially improve the…

Fast and dynamical control of quantum phases is highly desired in the application of quantum phenomena in devices. On the experimental side, ultrafast laser pulses provide an ideal platform to induce femtosecond dynamics in a variety of…

强关联电子 · 物理学 2020-10-21 Benedikt Fauseweh , Jian-Xin Zhu

In contrast to static holographic phase shifters, which are restricted to specific electron beam energies and microscope settings, Boersch phase shifters are promising for creating programmable arrays for generating two- and…

Using three-dimensional particle-in-cell simulations, we further investigate the electron and ion acceleration from femtosecond laser-plasma peeler scheme which was proposed in our recent paper (Shen et al 2021 Phys. Rev. X 11 041002). In…

等离子体物理 · 物理学 2023-02-15 X. F. Shen , A. Pukhov , B. Qiao
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