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Inferring the directionality of interactions between cellular processes is a major challenge in systems biology. Time-lagged correlations allow to discriminate between alternative models, but they still rely on assumed underlying…

定量方法 · 定量生物学 2017-11-15 Sourabh Lahiri , Philippe Nghe , Sander J. Tans , Martin Luc Rosinberg , David Lacoste

Finding interdependency relations between (possibly multivariate) time series provides valuable knowledge about the processes that generate the signals. Information theory sets a natural framework for non-parametric measures of several…

信息论 · 计算机科学 2016-02-09 German Gomez-Herrero , Wei Wu , Kalle Rutanen , Miguel C. Soriano , Gordon Pipa , Raul Vicente

Different measures of heart rate variability and particularly of respiratory sinus arrhythmia are widely used in research and clinical applications. Inspired by the ideas from the theory of coupled oscillators, we use simultaneous…

We use detrended fluctuation analysis (DFA) to study the dynamics of blood pressure oscillations and its feedback control in rats by analyzing systolic pressure time series before and after a surgical procedure that interrupts its control…

生物物理 · 物理学 2015-05-14 C. E. C. Galhardo , T. J. P. Penna , M. Argollo de Menezes , P. P. S. Soares

We develop numerical and analytical approaches to calculate mutual information between complete paths of two molecular components embedded into a larger reaction network. In particular, we focus on a continuous-time Markov chain formalism,…

分子网络 · 定量生物学 2022-08-09 Anne-Lena Moor , Christoph Zechner

We present a new framework for analyzing the evolution of information in geophysical systems. Understanding how information, and its counterpart, uncertainty, propagates is central to predictability studies and has significant implications…

信息论 · 计算机科学 2026-01-06 Peter Jan van Leeuwen

What does the informational complexity of dynamical networked systems tell us about intrinsic mechanisms and functions of these complex systems? Recent complexity measures such as integrated information have sought to operationalize this…

神经与进化计算 · 计算机科学 2017-07-06 Xerxes D. Arsiwalla , Pedro A. M. Mediano , Paul F. M. J. Verschure

Semi-Markov processes play an important role in the effective description of partially accessible systems in stochastic thermodynamics. They occur, for instance, in coarse-graining procedures such as state lumping and when analyzing waiting…

统计力学 · 物理学 2026-01-19 Alexander M. Maier , Jonas H. Fritz , Udo Seifert

We propose a new framework for measuring connectedness among financial variables that arises due to heterogeneous frequency responses to shocks. To estimate connectedness in short-, medium-, and long-term financial cycles, we introduce a…

统计方法学 · 统计学 2017-12-20 Jozef Barunik , Tomas Krehlik

Transfer Entropy and Directed Information are information-theoretic measures of the directional dependency between stochastic processes. Following the definitions of Schreiber and Massey in discrete time, we define and evaluate these…

概率论 · 数学 2016-04-08 Nigel J. Newton

Information theory is a powerful tool to express principles to drive autonomous systems because it is domain invariant and allows for an intuitive interpretation. This paper studies the use of the predictive information (PI), also called…

机器人学 · 计算机科学 2013-07-19 Georg Martius , Ralf Der , Nihat Ay

Information flow provides a natural measure for the causal interaction between dynamical events. This study extends our previous rigorous formalism of componentwise information flow to the bulk information flow between two complex…

神经元与认知 · 定量生物学 2021-12-30 X. San Liang

Small continuous sensory and mechanical perturbations have often been used to identify properties of the closed-loop neural control of posture and other systems that are approximately linear time invariant. Here we extend this approach to…

神经元与认知 · 定量生物学 2016-10-31 Tim Kiemel , David Logan , John J. Jeka

Empirical complex systems must differentially respond to external perturbations and, at the same time, internally distribute information to coordinate their components. While networked backbones help with the latter, they limit the…

物理与社会 · 物理学 2025-04-18 Arsham Ghavasieh , Manlio De Domenico

Neural systems process information across a broad range of intrinsic timescales, both within and across cortical areas. While such diversity is a hallmark of biological networks, its computational role in nonlinear information processing…

神经元与认知 · 定量生物学 2025-06-10 Tomoki Kurikawa

We analyzed the heartbeat time series of 12 human subjects exposed to progressive central hypovolemia with lower body negative pressure. Two data processing techniques based on wavelet transforms were used to determine the change in the…

统计力学 · 物理学 2007-05-23 Bruce J. West , Nicola Scafetta , William H. Cooke , Rita Balocchi

Modern clinical and epidemiological studies widely employ wearables to record parallel streams of real-time data on human physiology and behavior. With recent advances in distributional data analysis, these high-frequency data are now often…

统计方法学 · 统计学 2024-02-15 Rahul Ghosal , Sujit K. Ghosh , Jennifer A. Schrack , Vadim Zipunnikov

Understanding information processing in the brain requires the ability to determine the functional connectivity between the different regions of the brain. We present a method using transfer entropy to extract this flow of information…

神经元与认知 · 定量生物学 2019-03-06 Benjamin Walker , Katherine Newhall

Heartbeat rhythm and heart rate (HR) are important physiological parameters of the human body. This study presents an efficient multi-hierarchical spatio-temporal convolutional network that can quickly estimate remote physiological (rPPG)…

计算机视觉与模式识别 · 计算机科学 2023-04-24 Bin Li , Panpan Zhang , Jinye Peng , Hong Fu

Diffusion processes are instrumental to describe the movement of a continuous quantity in a generic network of interacting agents. Here, we present a probabilistic framework for diffusion in networks and propose to classify agent…

社会与信息网络 · 计算机科学 2015-08-28 Wai Hong Ronald Chan , Matthias Wildemeersch , Tony Q. S. Quek