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Functional networks provide a topological description of activity patterns in the brain, as they stem from the propagation of neural activity on the underlying anatomical or structural network of synaptic connections. This latter is well…

无序系统与神经网络 · 物理学 2021-02-11 Ali Safari , Paolo Moretti , Ibai Diez , Jesus M. Cortes , Miguel Ángel Muñoz

Topological Neural Networks (TNNs) incorporate higher-order relational information beyond pairwise interactions, enabling richer representations than Graph Neural Networks (GNNs). Concurrently, topological descriptors based on persistent…

机器学习 · 计算机科学 2024-06-06 Yogesh Verma , Amauri H Souza , Vikas Garg

Inferring topological and geometrical information from data can offer an alternative perspective on machine learning problems. Methods from topological data analysis, e.g., persistent homology, enable us to obtain such information,…

计算机视觉与模式识别 · 计算机科学 2018-02-19 Christoph Hofer , Roland Kwitt , Marc Niethammer , Andreas Uhl

This paper proposes a novel topological learning framework that integrates networks of different sizes and topology through persistent homology. Such challenging task is made possible through the introduction of a computationally efficient…

神经元与认知 · 定量生物学 2023-01-30 Tananun Songdechakraiwut , Moo K. Chung

Weighted digraphs are used to model a variety of natural systems and can exhibit interesting structure across a range of scales. In order to understand and compare these systems, we require stable, interpretable, multiscale descriptors. To…

代数拓扑 · 数学 2024-11-08 Thomas Chaplin , Heather A. Harrington , Ulrike Tillmann

Multiplexed imaging allows multiple cell types to be simultaneously visualised in a single tissue sample, generating unprecedented amounts of spatially-resolved, biological data. In topological data analysis, persistent homology provides…

We start with a simple introduction to topological data analysis where the most popular tool is called a persistent diagram. Briefly, a persistent diagram is a multiset of points in the plane describing the persistence of topological…

统计理论 · 数学 2017-06-28 Christophe Biscio , Jesper Møller

Topological correctness is critical for segmentation of tubular structures, which pervade in biomedical images. Existing topological segmentation loss functions are primarily based on the persistent homology of the image. They match the…

计算机视觉与模式识别 · 计算机科学 2025-10-29 Bo Wen , Haochen Zhang , Dirk-Uwe G. Bartsch , William R. Freeman , Truong Q. Nguyen , Cheolhong An

The application of network techniques to the analysis of neural data has greatly improved our ability to quantify and describe these rich interacting systems. Among many important contributions, networks have proven useful in identifying…

定量方法 · 定量生物学 2018-06-14 Ann E. Sizemore , Jennifer Phillips-Cremins , Robert Ghrist , Danielle S. Bassett

Representation learning on graphs is a fundamental problem that can be crucial in various tasks. Graph neural networks, the dominant approach for graph representation learning, are limited in their representation power. Therefore, it can be…

机器学习 · 计算机科学 2025-01-17 Zuoyu Yan , Qi Zhao , Ze Ye , Tengfei Ma , Liangcai Gao , Zhi Tang , Yusu Wang , Chao Chen

Neuronal morphology is an essential element for brain activity and function. We take advantage of current availability of brain-wide neuron digital reconstructions of the Pyramidal cells from a mouse brain, and analyze several emergent…

动力系统 · 数学 2018-10-09 Congping Lin , Yuanfei Huang , Tingwei Quan , Yiwei Zhang

Different cell types aggregate and sort into hierarchical architectures during the formation of animal tissues. The resulting spatial organization depends (in part) on the strength of adhesion of one cell type to itself relative to other…

定量方法 · 定量生物学 2023-08-02 Dhananjay Bhaskar , William Y. Zhang , Alexandria Volkening , Björn Sandstede , Ian Y. Wong

The complexity of a neuronal cell shape is known to be related to its function. Specifically, among other indicators, a decreased complexity in the dendritic trees of cortical pyramidal neurons has been associated with mental retardation.…

定量方法 · 定量生物学 2007-05-23 M. S. Barbosa , L. da F. Costa , E. S. Bernardes , G. Ramakers , J. van Pelt

Persistent homology is a mathematical tool used for studying the shape of data by extracting its topological features. It has gained popularity in network science due to its applicability in various network mining problems, including…

代数拓扑 · 数学 2023-06-21 Mehmet Emin Aktas , Thu Nguyen , Rakin Riza , Muhammad Ifte Islam , Esra Akbas

We use topological data analysis to study "functional networks" that we construct from time-series data from both experimental and synthetic sources. We use persistent homology with a weight rank clique filtration to gain insights into…

定量方法 · 定量生物学 2017-05-24 Bernadette J. Stolz , Heather A. Harrington , Mason A. Porter

This article aims to study the topological invariant properties encoded in node graph representational embeddings by utilizing tools available in persistent homology. Specifically, given a node embedding representation algorithm, we…

机器学习 · 计算机科学 2021-10-12 Mustafa Hajij , Ghada Zamzmi , Xuanting Cai

Computational topology provides a tool, persistent homology, to extract quantitative descriptors from structured objects (images, graphs, point clouds, etc). These descriptors can then be involved in optimization problems, typically as a…

计算几何 · 计算机科学 2026-03-27 Mathieu Carriere , Yuichi Ike , Théo Lacombe , Naoki Nishikawa

Persistent homology analysis provides means to capture the connectivity structure of data sets in various dimensions. On the mathematical level, by defining a metric between the objects that persistence attaches to data sets, we can…

机器学习 · 计算机科学 2019-06-12 Henri Riihimäki , José Licón-Saláiz

Persistent homology has been widely used to discover hidden topological structures in data across various applications, including music data. To apply persistent homology, a distance or metric must be defined between points in a point cloud…

声音 · 计算机科学 2025-12-15 Eunwoo Heo , Byeongchan Choi , Myung ock Kim , Mai Lan Tran , Jae-Hun Jung

We propose a topological framework to study the evolution of Alzheimer's disease, the most common neurodegenerative disease. The modeling of this disease starts with the representation of the brain connectivity as a graph and the seeding of…

神经元与认知 · 定量生物学 2023-09-20 Christian Goodbrake , David Beers , Travis B. Thompson , Heather A. Harrington , Alain Goriely