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Introduction: The value of integrating federal HIV services data with HIV surveillance is currently unknown. Upstream and complete case capture is essential in preventing future HIV transmission. Methods: This study integrated Ryan White,…

机器学习 · 计算机科学 2023-04-21 Nick Williams

In this work we develop a stochastic model of acute HIV infection, based on the well-known standard model, that allows us to simulate the complex mutation pathways of HIV escape from multiple CTL responses. Under this model, we describe two…

种群与进化 · 定量生物学 2012-08-16 Sivan Leviyang

In this work, we propose a novel generative method to identify the causal impact and apply it to prediction tasks. We conduct causal impact analysis using interventional and counterfactual perspectives. First, applying interventions, we…

机器学习 · 计算机科学 2025-09-03 Soma Bandyopadhyay , Sudeshna Sarkar

Naomi is a spatial evidence synthesis model used to produce district-level HIV epidemic indicators in sub-Saharan Africa. Multiple outcomes of policy interest, including HIV prevalence, HIV incidence, and antiretroviral therapy treatment…

统计方法学 · 统计学 2025-08-22 Adam Howes , Alex Stringer , Seth R. Flaxman , Jeffrey W. Imai-Eaton

Although deep learning techniques show promising results for many neuroimaging tasks in research settings, they have not yet found widespread use in clinical scenarios. One of the reasons for this problem is that many machine learning…

图像与视频处理 · 电气工程与系统科学 2024-12-05 Vibujithan Vigneshwaran , Erik Ohara , Matthias Wilms , Nils Forkert

Causal influence measures for machine learnt classifiers shed light on the reasons behind classification, and aid in identifying influential input features and revealing their biases. However, such analyses involve evaluating the classifier…

机器学习 · 计算机科学 2018-04-10 Shayak Sen , Piotr Mardziel , Anupam Datta , Matthew Fredrikson

The importance of clinical variables in the prognosis of the disease is explained using statistical correlation or machine learning (ML). However, the predictive importance of these variables may not represent their causal relationships…

机器学习 · 统计学 2025-06-04 Yina Hou , Shourav B. Rabbani , Liang Hong , Norou Diawara , Manar D. Samad

Objective. To pilot test an artificial intelligence (AI) algorithm that selects peer change agents (PCA) to disseminate HIV testing messaging in a population of homeless youth. Methods. We recruited and assessed 62 youth at baseline, 1…

人工智能 · 计算机科学 2016-08-22 Eric Rice , Robin Petering , Jaih Craddock , Amanda Yoshioka-Maxwell , Amulya Yadav , Milind Tambe

The cause of failure in cohort studies that involve competing risks is frequently incompletely observed. To address this, several methods have been proposed for the semiparametric proportional cause-specific hazards model under a missing at…

统计方法学 · 统计学 2020-02-24 Giorgos Bakoyannis , Ying Zhang , Constantin T. Yiannoutsos

Causal inference in longitudinal biomedical data remains a central challenge, especially in psychiatry, where symptom heterogeneity and latent confounding frequently undermine classical estimators. Most existing methods for treatment effect…

机器学习 · 计算机科学 2025-07-28 Eric V. Strobl

The paper focuses on identifying the causes of student performance to provide personalized recommendations for improving pass rates. We introduce the need to move beyond predictive models and instead identify causal relationships. We…

计算机与社会 · 计算机科学 2023-09-26 Bevan I. Smith

In this paper, we present a novel method to automatically classify medical images that learns and leverages weak causal signals in the image. Our framework consists of a convolutional neural network backbone and a causality-extractor module…

计算机视觉与模式识别 · 计算机科学 2023-09-20 Gianluca Carloni , Eva Pachetti , Sara Colantonio

Causal identification of treatment effects for infectious disease outcomes in interconnected populations is challenging because infection outcomes may be transmissible to others, and treatment given to one individual may affect others'…

统计方法学 · 统计学 2021-05-11 Xiaoxuan Cai , Eben Kenah , Forrest W. Crawford

Certain subpopulations like female sex workers (FSW), men who have sex with men (MSM), and people who inject drugs (PWID) often have higher prevalence of HIV/AIDS and are difficult to map directly due to stigma, discrimination, and…

应用统计 · 统计学 2021-06-14 Ian Laga , Xiaoyue Niu , Le Bao

Given a collection of features available for inclusion in a predictive model, it may be of interest to quantify the relative importance of a subset of features for the prediction task at hand. For example, in HIV vaccine trials, participant…

统计方法学 · 统计学 2025-03-27 Charles J. Wolock , Peter B. Gilbert , Noah Simon , Marco Carone

For settings with a binary treatment and a binary outcome, instrumental variables can be used to construct bounds on a causal treatment effect. With continuous outcomes, meaningful bounds are more difficult to obtain because the domain of…

统计方法学 · 统计学 2013-03-26 Tao Liu , Joseph W. Hogan

Evaluating the performance of heuristic optimisation algorithms is essential to determine how well they perform under various conditions. Recently, the BIAS toolbox was introduced as a behaviour benchmark to detect structural bias (SB) in…

神经与进化计算 · 计算机科学 2023-04-05 Bas van Stein , Diederick Vermetten , Fabio Caraffini , Anna V. Kononova

Measuring the causal impact of an advertising campaign on sales is an essential task for advertising companies. Challenges arise when companies run advertising campaigns in multiple stores which are spatially correlated, and when the sales…

统计方法学 · 统计学 2018-03-13 Bo Ning , Subhashis Ghosal , Jewell Thomas

Motivation: HIV is difficult to treat because its virus mutates at a high rate and mutated viruses easily develop resistance to existing drugs. If the relationships between mutations and drug resistances can be determined from historical…

定量方法 · 定量生物学 2019-07-08 Li Xing , Mary Lesperance , Xuekui Zhang

We present a workflow for clinical data analysis that relies on Bayesian Structure Learning (BSL), an unsupervised learning approach, robust to noise and biases, that allows to incorporate prior medical knowledge into the learning process…

机器学习 · 计算机科学 2022-10-12 Elisa Ferrari , Luna Gargani , Greta Barbieri , Lorenzo Ghiadoni , Francesco Faita , Davide Bacciu