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During an infectious disease outbreak, biases in the data and complexities of the underlying dynamics pose significant challenges in mathematically modelling the outbreak and designing policy. Motivated by the ongoing response to COVID-19,…

Non-pharmaceutical interventions (NPIs) such as quarantine, self-isolation, social distancing, and virus-contact tracing can greatly reduce the spread of the virus during a pandemic. In the wave of the COVID-19 pandemic, many countries have…

物理与社会 · 物理学 2020-12-16 Jingjing He , Xuefei Guan , Xiaochang Duan , Tian Shen , Jing Lin

We propose a general Bayesian approach to modeling epidemics such as COVID-19. The approach grew out of specific analyses conducted during the pandemic, in particular an analysis concerning the effects of non-pharmaceutical interventions…

应用统计 · 统计学 2021-01-01 Samir Bhatt , Neil Ferguson , Seth Flaxman , Axel Gandy , Swapnil Mishra , James A. Scott

A novel predictive modeling framework for the spread of infectious diseases using high dimensional partial differential equations is developed and implemented. A scalar function representing the infected population is defined on a…

种群与进化 · 定量生物学 2020-07-06 Sashikumaar Ganesan , Deepak Subramani

To date, the only effective means to respond to the spreading of COVID-19 pandemic are non-pharmaceutical interventions (NPIs), which entail policies to reduce social activity and mobility restrictions. Quantifying their effect is…

物理与社会 · 物理学 2021-03-01 Francesco Parino , Lorenzo Zino , Maurizio Porfiri , Alessandro Rizzo

The recent coronavirus disease (COVID-19) outbreak has dramatically increased the public awareness and appreciation of the utility of dynamic models. At the same time, the dissemination of contradictory model predictions has highlighted…

种群与进化 · 定量生物学 2020-06-26 Gemma Massonis , Julio R. Banga , Alejandro F. Villaverde

We present EPITIME (EPidemic Integral models TIMe profile Explorer), a computational framework for the simulation of two classes of integral epidemic models: an age of infection model and an information dependent behavioural model. The…

定量方法 · 定量生物学 2026-05-04 Bruno Buonomo , Eleonora Messina , Claudia Panico , Mario Pezzella , Gaetano Zanghirati

Since the outbreak of COVID-19, an astronomical number of publications on the pandemic dynamics appeared in the literature, of which many use the susceptible infected removed (SIR) and susceptible exposed infected removed (SEIR) models, or…

机器学习 · 计算机科学 2021-11-03 Hua-Liang Wei , S. A. Billings

Diverse non-pharmacological interventions (NPIs), serving as the primary approach for COVID-19 control prior to pharmaceutical interventions, showed heterogeneous spatiotemporal effects on pandemic management. Investigating the dynamic…

应用统计 · 统计学 2023-12-25 Binbin Lin , Yimin Dai , Lei Zou , Ning Ning

A model-based signal processing framework is proposed for pandemic trend forecasting and control, by using non-pharmaceutical interventions (NPI) at regional and country levels worldwide. The control objective is to prescribe quantifiable…

最优化与控制 · 数学 2021-11-23 Reza Sameni

We propose a multi-layer network model for the spread of COVID-19 that accounts for interactions within the family, between schoolmates, and casual contacts in the population. We utilize the proposed model-calibrated on epidemiological and…

物理与社会 · 物理学 2021-03-24 Christian Bongiorno , Lorenzo Zino

A reasonable prediction of infectious diseases transmission process under different disease control strategies is an important reference point for policy makers. Here we established a dynamic transmission model via Python and realized…

种群与进化 · 定量生物学 2021-02-23 Yuxuan Zhang , Chen Gong , Dawei Li , Zhi-Wei Wang , Shengda D Pu , Alex W Robertson , Hong Yu , John Parrington

Mathematical modeling is one of the key factors of the effective control of newly found infectious diseases, such as COVID-19. Our knowledge about the parameters and the course of the infection is highly limited in the beginning of the…

定量方法 · 定量生物学 2021-10-13 Péter Boldog , Norbert Bogya , Zsolt Vizi

Strategies adopted globally to mitigate the threat of COVID-19 have primarily involved lockdown measures with substantial economic and social costs with varying degrees of success. Morbidity patterns of COVID-19 variants have a strong…

We present a unifying, tractable approach for studying the spread of viruses causing complex diseases requiring to be modeled using a large number of types (e.g., infective stage, clinical state, risk factor class). We show that recording…

For the description of a pandemic mathematical models could be interesting. Both for physicians and politicians as a base for decisions to treat the disease. The responsible estimation of parameters is a main issue of mathematical pandemic…

种群与进化 · 定量生物学 2020-04-15 Günter Bärwolff

We demonstrate an approach to replicate and forecast the spread of the SARS-CoV-2 (COVID-19) pandemic using the toolkit of probabilistic programming languages (PPLs). Our goal is to study the impact of various modeling assumptions and…

机器学习 · 统计学 2022-03-08 Swapneel Mehta , Noah Kasmanoff

Mathematical modeling of epidemic spreading has been widely adopted to estimate the threats of epidemic diseases (i.e., the COVID-19 pandemic) as well as to evaluate epidemic control interventions. The indoor place is considered to be a…

物理与社会 · 物理学 2022-09-14 Yao Xiao , Mofeng Yang , Zheng Zhu , Hai Yang , Lei Zhang , Sepehr Ghader

Coronavirus COVID-19 spreads through the population mostly based on social contact. To gauge the potential for widespread contagion, to cope with associated uncertainty and to inform its mitigation, more accurate and robust modelling is…

The COVID-19 pandemic has led to significant changes in how people are currently living their lives. To determine how to best reduce the effects of the pandemic and start reopening societies, governments have drawn insights from…

其他定量生物学 · 定量生物学 2020-09-08 Heather Z. Brooks , Unchitta Kanjanasaratool , Yacoub H. Kureh , Mason A. Porter
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