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Developing reliable methods to discriminate different transient brain states that change over time is a key neuroscientific challenge in brain imaging studies. Topological data analysis (TDA), a novel framework based on algebraic topology,…

神经元与认知 · 定量生物学 2023-12-19 Moo K. Chung , Soumya Das , Hernando Ombao

Topological data analysis (TDA) has become a powerful approach over the last twenty years, mainly due to its ability to capture the shape and the geometry inherent in the data. Persistence homology, which is a particular tool in TDA, has…

神经元与认知 · 定量生物学 2024-01-12 Anass B. El-Yaagoubi , Shuhao Jiao , Moo K. Chung , Hernando Ombao

Persistent homology offers a powerful tool for extracting hidden topological signals from brain networks. It captures the evolution of topological structures across multiple scales, known as filtrations, thereby revealing topological…

Almost all statistical and machine learning methods in analyzing brain networks rely on distances and loss functions, which are mostly Euclidean or matrix norms. The Euclidean or matrix distances may fail to capture underlying subtle…

计算几何 · 计算机科学 2021-02-18 Moo K. Chung , Alexander Smith , Gary Shiu

We introduce a novel, data-driven topological data analysis (TDA) approach for embedding brain networks into a lower-dimensional space in quantifying the dynamics of temporal lobe epilepsy (TLE) obtained from resting-state functional…

In this article, we introduce a Topological Data Analysis (TDA) pipeline for neural spike train data. Understanding how the brain transforms sensory information into perception and behavior requires analyzing coordinated neural population…

统计方法学 · 统计学 2025-12-10 Cagatay Ayhan , Audrey N. Nash , Roberto Vincis , Martin Bauer , Richard Bertram , Tom Needham

Childhood maltreatment may adversely affect brain development and consequently influence behavioral, emotional, and psychological patterns during adulthood. In this study, we propose an analytical pipeline for modeling the altered…

神经元与认知 · 定量生物学 2023-11-16 Moo K. Chung , Tahmineh Azizi , Jamie L. Hanson , Andrew L. Alexander , Richard J. Davidson , Seth D. Pollak

We develop a framework for analyzing multivariate time series using topological data analysis (TDA) methods. The proposed methodology involves converting the multivariate time series to point cloud data, calculating Wasserstein distances…

代数拓扑 · 数学 2020-12-29 Chengyuan Wu , Carol Anne Hargreaves

In this paper we develop a novel Topological Data Analysis (TDA) approach for studying graph representations of time series of dynamical systems. Specifically, we show how persistent homology, a tool from TDA, can be used to yield a…

混沌动力学 · 物理学 2020-01-28 Audun Myers , Elizabeth Munch , Firas A. Khasawneh

Traditional Topological Data Analysis (TDA) methods, such as Persistent Homology (PH), rely on distance measures (e.g., cross-correlation, partial correlation, coherence, and partial coherence) that are symmetric by definition. While useful…

神经元与认知 · 定量生物学 2024-07-19 Anass B. El-Yaagoubi , Moo K. Chung , Hernando Ombao

Over the last two decades, topological data analysis (TDA) has emerged as a very powerful data analytic approach which can deal with various data modalities of varying complexities. One of the most commonly used tools in TDA is persistent…

统计方法学 · 统计学 2025-12-08 Anass El Yaagoubi Bourakna , Moo K. Chung , Hernando Ombao

Understanding brain dynamics through functional Magnetic Resonance Imaging (fMRI) remains a fundamental challenge in neuroscience, particularly in capturing how the brain transitions between various functional states. Recently,…

图像与视频处理 · 电气工程与系统科学 2025-07-01 Yanwu Yang , Thomas Wolfers

Functional brain connectivity changes dynamically over time, making its representation challenging for learning on non-Euclidean data. We present a framework that encodes dynamic functional connectivity as an image representation of…

神经元与认知 · 定量生物学 2025-11-14 Peilin He , Tananun Songdechakraiwut

Interacting, self-propelled particles such as epithelial cells can dynamically self-organize into complex multicellular patterns, which are challenging to classify without a priori information. Classically, different phases and phase…

定量方法 · 定量生物学 2021-01-19 Dhananjay Bhaskar , William Y. Zhang , Ian Y. Wong

Topological data analysis (TDA) is an emerging technique for biological signal processing. TDA leverages the invariant topological features of signals in a metric space for robust analysis of signals even in the presence of noise. In this…

代数拓扑 · 数学 2024-01-11 Shashank Manjunath , Jose A. Perea , Aarti Sathyanarayana

Despite the remarkable accuracies attained by machine learning classifiers to separate complex datasets in a supervised fashion, most of their operation falls short to provide an informed intuition about the structure of data, and, what is…

机器学习 · 计算机科学 2023-03-09 Aina Ferrà , Gloria Cecchini , Fritz-Pere Nobbe Fisas , Carles Casacuberta , Ignasi Cos

Topological Data Analysis (TDA) is an approach to handle with big data by studying its shape. A main tool of TDA is the persistence diagram, and one can use it to compare data sets. One approach to learn on the similarity between two…

应用统计 · 统计学 2020-03-04 Sarit Agami

Topological data analysis (TDA) is a branch of computational mathematics, bridging algebraic topology and data science, that provides compact, noise-robust representations of complex structures. Deep neural networks (DNNs) learn millions of…

Continual learning in neural networks suffers from a phenomenon called catastrophic forgetting, in which a network quickly forgets what was learned in a previous task. The human brain, however, is able to continually learn new tasks and…

机器学习 · 计算机科学 2022-10-07 Tananun Songdechakraiwut , Xiaoshuang Yin , Barry D. Van Veen

This paper proposes a novel topological learning framework that integrates networks of different sizes and topology through persistent homology. Such challenging task is made possible through the introduction of a computationally efficient…

神经元与认知 · 定量生物学 2023-01-30 Tananun Songdechakraiwut , Moo K. Chung
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