相关论文: Cardiac Electrophysiology Meshfree Modeling throug…

We present a novel mathematical model that simulates myocardial blood perfusion by embedding multiscale and multiphysics features. Our model incorporates cardiac electrophysiology, active and passive mechanics, hemodynamics, reduced valve…

Cardiac deformation is a crucial biomarker for the evaluation of cardiac function. Current methods for estimating cardiac strain might underestimate local deformation due to through-plane motion and segmental averaging. Mesh-based mapping…

We propose a novel neural deformable model (NDM) targeting at the reconstruction and modeling of 3D bi-ventricular shape of the heart from 2D sparse cardiac magnetic resonance (CMR) imaging data. We model the bi-ventricular shape using…

Cardiac fluid dynamics fundamentally involves interactions between complex blood flows and the structural deformations of the muscular heart walls and the thin, flexible valve leaflets. There has been longstanding scientific, engineering,…

Clinical oriented applications of computational electrocardiology require efficient and reliable identification of patient-specific parameters of mathematical models based on available measures. In particular, the estimation of cardiac…

Simultaneous electrocardiography (ECG) and phonocardiogram (PCG) provide a comprehensive, multimodal perspective on cardiac function by capturing the heart's electrical and mechanical activities, respectively. However, the distinct and…

Electrocardiogram (ECG) is one of the non-invasive and low-risk methods to monitor the condition of the human heart. Any abnormal pattern(s) in the ECG signal is an indicative measure of malfunctioning of the heart, termed as arrhythmia.…

Computational fluid dynamics (CFD) based simulation of coronary blood flow provides valuable hemodynamic markers, such as pressure gradients, for diagnosing coronary artery disease (CAD). However, CFD is computationally expensive,…

We present a deep learning model to automatically generate computer models of the human heart from patient imaging data with an emphasis on its capability to generate thin-walled cardiac structures. Our method works by deforming a template…

In this paper, we propose an enhanced 3D myocardial strain estimation procedure, which combines complementary displacement information from multiple orientations of a single imaging modality (untagged CMR SSFP images). To estimate…

Many strides have been made in semantic segmentation of multiple classes within an image. This has been largely due to advancements in deep learning and convolutional neural networks (CNNs). Features within a CNN are automatically learned…

Personalized virtual heart models have demonstrated increasing potential for clinical use, although the estimation of their parameters given patient-specific data remain a challenge. Traditional physics-based modeling approaches are…

We develop a minimal whole-heart model that describes cardiac electrical conduction and simulate a basic three-lead electrocardiogram (ECG). We compare our 3-lead ECG model with clinical data from a Norwegian athlete database. The results…

We present a hybrid vertex/cell-centred model for mechanically simulating planar cellular monolayers undergoing cell reorganisation. Cell centres are represented by a triangular nodal network, while the cell boundaries are formed by an…

We analyze a Balancing Domain Decomposition by Constraints (BDDC) preconditioner for the solution of three dimensional composite Discontinuous Galerkin discretizations of reaction-diffusion systems of ordinary and partial differential…

Heart failure is one of the most common causes of death in the western world. Many heart problems are linked to disturbances in cardiac electrical activity, such as wave re-entry caused by ischaemia. In terms of mathematical modelling, the…

Recovering the 3D motion of the heart from cine cardiac magnetic resonance (CMR) imaging enables the assessment of regional myocardial function and is important for understanding and analyzing cardiovascular disease. However, 3D cardiac…

Multiphysics and multiscale mathematical models enable the non-invasive study of cardiac function. These models often rely on simplifying assumptions that neglect certain biophysical processes to balance fidelity and computational cost. In…

We present a loosely coupled scheme for the numerical simulation of the cardiac electro-fluid-structure interaction problem, whose solution is typically computationally intensive due to the need to suitably treat the coupling of the…

Learning neural operators on heterogeneous and irregular geometries remains a fundamental challenge, as existing approaches typically rely on structured discretisations or explicit mappings to a shared reference domain. We propose a unified…