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We propose a novel partitioned scheme based on Eikonal equations to model the coupled propagation of the electrical signal in the His-Purkinje system and in the myocardium for cardiac electrophysiology. This scheme allows, for the first…

Myocardial infarction (MI) is one of the most prevalent cardiovascular diseases with associated clinical decision-making typically based on single-valued imaging biomarkers. However, such metrics only approximate the complex 3D structure…

计算机视觉与模式识别 · 计算机科学 2023-07-17 Marcel Beetz , Yilong Yang , Abhirup Banerjee , Lei Li , Vicente Grau

Developing efficient path integral (PI) methods for atomistic simulations of vibrational spectra in heterogeneous condensed phases and interfaces has long been a challenging task. Here, we present the h-CMD method, short for hybrid centroid…

化学物理 · 物理学 2025-05-08 Dil K. Limbu , Nathan London , Md Omar Faruque , Mohammad R. Momeni

Cardiovascular disease (CVD) is a leading cause of mortality worldwide. Electrocardiograms (ECGs) are the most widely used non-invasive tool for cardiac assessment, yet large, well-annotated ECG corpora are scarce due to cost, privacy, and…

机器学习 · 计算机科学 2025-11-14 Xiaoda Wang , Kaiqiao Han , Yuhao Xu , Xiao Luo , Yizhou Sun , Wei Wang , Carl Yang

Background: Extensive clinical evidence suggests that a preventive screening of coronary heart disease (CHD) at an earlier stage can greatly reduce the mortality rate. We use 64 two-dimensional speckle tracking echocardiography (2D-STE)…

机器学习 · 统计学 2021-05-21 Jingyi Zhang , Huolan Zhu , Yongkai Chen , Chenguang Yang , Huimin Cheng , Yi Li , Wenxuan Zhong , Fang Wang

We develop a new meshfree geometric multilevel (MGM) method for solving linear systems that arise from discretizing elliptic PDEs on surfaces represented by point clouds. The method uses a Poisson disk sampling-type technique for coarsening…

数值分析 · 数学 2022-04-14 Grady B. Wright , Andrew M. Jones , Varun Shankar

The realisation of precision cardiology requires novel techniques for the non-invasive characterisation of individual patients' cardiac function to inform therapeutic and diagnostic decision-making. The electrocardiogram (ECG) is the most…

Time-evolving magnetohydrodynamic (MHD) coronal modeling, driven by a series of time-dependent photospheric magnetograms, represents a new generation of coronal simulations. This approach offers greater realism compared to traditional…

Deformation modeling of cardiac muscle is an important issue in the field of cardiac analysis. Many approaches have been developed to better estimate the cardiac muscle deformation, and to obtain a practical model to be used in diagnostic…

计算工程、金融与科学 · 计算机科学 2015-12-01 Ahmadreza Baghaie , Hamid Abrishami Moghaddam

Wearable sensing devices, such as Electrocardiogram (ECG) heart-rate monitors, will play a crucial role in the future of digital health. This continuous monitoring leads to massive unlabeled data, incentivizing the development of…

机器学习 · 计算机科学 2025-03-03 Adtian Atienza , Gouthamaan Manimaran , Jakob E. Bardram , Sadasivan Puthusserypady

Electrocardiogram (ECG) is a widely used non-invasive diagnostic tool for heart diseases. Many studies have devised ECG analysis models (e.g., classifiers) to assist diagnosis. As an upstream task, researches have built generative models to…

机器学习 · 计算机科学 2023-05-30 Jintai Chen , Kuanlun Liao , Kun Wei , Haochao Ying , Danny Z. Chen , Jian Wu

Four-dimensional (4D) left ventricular myocardial velocity mapping (MVM) is a cardiac magnetic resonance (CMR) technique that allows assessment of cardiac motion in three orthogonal directions. Accurate and reproducible delineation of the…

图像与视频处理 · 电气工程与系统科学 2020-12-23 Yinzhe Wu , Suzan Hatipoglu , Diego Alonso-Álvarez , Peter Gatehouse , David Firmin , Jennifer Keegan , Guang Yang

This study introduces an improved VMD based signal decomposition methodology for non-contact heartbeat estimation using millimeterwave (mmWave) radar. Specifically, we first analyze the signal model of the mmWave radar system. The…

信号处理 · 电气工程与系统科学 2025-02-18 Boyuan Gu , Yanhui Yang , Siyu You , Haiyang Sun , Jiahui Sun , Shisheng Guo

When modelling tissue-level cardiac electrophysiology, continuum approximations to the discrete cell-level equations are used to maintain computational tractability. One of the most commonly used models is represented by the bidomain…

计算工程、金融与科学 · 计算机科学 2012-08-22 Doug Bruce , Pras Pathmanathan , Jonathan P. Whiteley

We present a mean-field approach to simulating merging processes of two spherical collisionless stellar systems. This approach is realized with a self-consistent field (SCF) method in which the full spatial dependence of the density and…

天体物理仪器与方法 · 物理学 2019-04-17 Shunsuke Hozumi , Masaki Iwasawa , Keigo Nitadori

Computer modeling of multicellular systems has been a valuable tool for interpreting and guiding in vitro experiments relevant to embryonic morphogenesis, tumor growth, angiogenesis and, lately, structure formation following the printing of…

生物物理 · 物理学 2015-05-28 Elijah Flenner , Lorant Janosi , Bogdan Barz , Adrian Neagu , Gabor Forgacs , Ioan Kosztin

Accurate diagnosis is required before performing proper treatments for coronary heart disease. Machine learning based approaches have been proposed by many researchers to improve the accuracy of coronary heart disease diagnosis. Ensemble…

机器学习 · 计算机科学 2020-07-07 Kuntoro Adi Nugroho , Noor Akhmad Setiawan , Teguh Bharata Adji

Feature tracking Cardiac Magnetic Resonance (CMR) has recently emerged as an area of interest for quantification of regional cardiac function from balanced, steady state free precession (SSFP) cine sequences. However, currently available…

计算机视觉与模式识别 · 计算机科学 2017-04-13 Davis M. Vigneault , Weidi Xie , David A. Bluemke , J. Alison Noble

Computational fluid dynamics (CFD) simulation provides valuable information on blood flow from the vascular geometry. However, it requires extracting precise models of arteries from low-resolution medical images, which remains challenging.…

计算几何 · 计算机科学 2023-06-14 Méghane Decroocq , Carole Frindel , Pierre Rougé , Makoto Ohta , Guillaume Lavoué

Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) are a promising therapy for regenerating myocardium after infarction, but their use is limited by graft-related arrhythmias that frequently occur shortly after transplantation.…

组织与器官 · 定量生物学 2026-05-05 Suran Galappaththige , Vadim N Biktashev , Faisal J Alibhai , Michael Laflamme