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The rapid spread of the Coronavirus (COVID-19) confronts policy makers with the problem of measuring the effectiveness of containment strategies, balancing public health considerations with the economic costs of social distancing measures.…

物理与社会 · 物理学 2021-04-02 Claudius Gros , Roser Valenti , Lukas Schneider , Kilian Valenti , Daniel Gros

As humanity struggles to contain the global Covid-19 infection, prophylactic actions are grandly slowed down by the shortage of testing kits. Governments have taken several measures to work around this shortage: the FDA has become more…

Globally, the outbreaks of infectious diseases have exerted an extremely profound and severe influence on health security and the economy. During the critical phases of epidemics, devising effective intervention measures poses a significant…

机器学习 · 计算机科学 2025-05-08 Baida Zhang , Yakai Chen , Huichun Li , Zhenghu Zu

In the absence of any available vaccines or drugs, prevention of the spread of Coronavirus Disease 2019 (COVID-19) pandemic is being achieved by putting many mitigation measures in place. It is indispensable to have robust and reliable ways…

种群与进化 · 定量生物学 2020-04-17 Gaurav Goswami , Jayanti Prasad , Mansi Dhuria

This paper analyses the optimal control of infectious disease propagation using a classic susceptible-infected-recovered (SIR) model characterised by permanent immunity and the absence of available vaccines. The control is performed over a…

Testing symptomatic individuals for a disease can deliver treatment resources, if tests' results turn positive, which speeds up their treatment and might also decrease individuals' contacts to other ones. An imperfect test, however, might…

种群与进化 · 定量生物学 2015-06-25 Daniel A. M. Villela

Optimal control theory in epidemiology has been used to establish the most effective intervention strategies for managing and mitigating the spread of infectious diseases while considering constraints and costs. Using Pontryagin's Maximum…

物理与社会 · 物理学 2025-08-08 Sandra Montes-Olivas , Adam J. Kucharski , Michael B. Gravenor , Simon D. W. Frost

In times of outbreaks, an essential requirement for better monitoring is the evaluation of the number of undiagnosed infected individuals. An accurate estimate of this fraction is crucial for the assessment of the situation and the…

种群与进化 · 定量生物学 2021-03-17 Akiva B. Melka , Yoram Louzoun

The detection and management of diseases become quite complicated when pathogens contain asymptomatic phenotypes amongst their ranks, as evident during the recent COVID-19 pandemic. Spreading of diseases has been studied extensively under…

物理与社会 · 物理学 2021-10-27 Saptarshi Sinha , Deep Nath , Soumen Roy

Intent of this research is to explore how mathematical models, specifically Susceptible-Infected-Removed (SIR) model, can be utilized to forecast peak outbreak timeline of COVID-19 epidemic amongst a population of interest starting from the…

种群与进化 · 定量生物学 2020-09-14 Amit Tewari

This study focuses on investigating the manner in which a prompt quarantine measure suppresses epidemics in networks. A simple and ideal quarantine measure is considered in which an individual is detected with a probability immediately…

物理与社会 · 物理学 2017-08-16 Takehisa Hasegawa , Koji Nemoto

We consider real-time timely tracking of infection status (e.g., covid-19) of individuals in a population. In this work, a health care provider wants to detect infected people as well as people who recovered from the disease as quickly as…

计算机与社会 · 计算机科学 2020-12-29 Melih Bastopcu , Sennur Ulukus

Social distancing strategies have been adopted by governments to manage the COVID-19 pandemic, since the first outbreak began. However, further epidemic waves keep out the return of economic and social activities to their standard levels of…

最优化与控制 · 数学 2021-06-07 J. E. Sereno , A. D' Jorge , A. Ferramosca , E. A. Hernandez-Vargas , A. H. Gonzalez

Epidemic decision-making can effectively help the government to comprehensively consider public security and economic development to respond to public health and safety emergencies. Epidemic decision-making can effectively help the…

机器学习 · 计算机科学 2023-11-06 Yangxi Zhou , Junping Du , Zhe Xue , Zhenhui Pan , Weikang Chen

Optimizing the impact on the economy of control strategies aiming at containing the spread of COVID-19 is a critical challenge. We use daily new case counts of COVID-19 patients reported by local health administrations from different…

种群与进化 · 定量生物学 2021-03-12 Afroza Shirin , Yen Ting Lin , Francesco Sorrentino

Epidemics of infectious diseases are among the largest threats to the quality of life and the economic and social well-being of developing countries. The arsenal of measures against such epidemics is well-established, but costly and…

社会与信息网络 · 计算机科学 2013-07-09 Mohamed Kafsi , Ehsan Kazemi , Lucas Maystre , Lyudmila Yartseva , Matthias Grossglauser , Patrick Thiran

Susceptible-Infected-Recovered (SIR) models have been used for decades to understand epidemic outbreak dynamics. We develop an SIR model specifically designed to study the effects of population behavior with respect to health and…

种群与进化 · 定量生物学 2023-08-03 Jasmin Nunuvero , Angelique Santiago , Moshe Cohen , Anca Radulescu

We investigate the time-optimal control problem in SIR (Susceptible-Infected-Recovered) epidemic models, focusing on different control policies: vaccination, isolation, culling, and reduction of transmission. Applying the Pontryagin's…

最优化与控制 · 数学 2017-06-15 Luca Bolzoni , Elena Bonacini , Cinzia Soresina , Maria Groppi

I employ a simple mathematical model of an epidemic process to evaluate how four basic quantities: the reproduction number (R), the numbers of sensitive (S) and infectious individuals(I), and total community size (N) affect strategies to…

种群与进化 · 定量生物学 2020-05-08 Michael E. Hochberg

Optimal control of interdependent epidemics spreading over complex networks is a critical issue. We first establish a framework to capture the coupling between two epidemics, and then analyze the system's equilibrium states by categorizing…

系统与控制 · 计算机科学 2017-10-19 Juntao Chen , Rui Zhang , Quanyan Zhu