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We propose a versatile model with a flexible choice of control for an early-pandemic outbreak prevention when vaccine/drug is not yet available. At that stage, control is often limited to non-medical interventions like social distancing and…

最优化与控制 · 数学 2024-06-14 Alexandra Smirnova , Xiaojing Ye

A simple, but ``classical``, stochastic model for epidemic spread in a finite, but large, population is studied. The progress of the epidemic can be divided into three different phases that requires different tools to analyse. Initially the…

种群与进化 · 定量生物学 2018-05-29 Åke Svensson

A crucial aspect of managing a public health crisis is to effectively balance prevention and mitigation strategies, while taking their socio-economic impact into account. In particular, determining the influence of different…

During the early months of the current COVID-19 pandemic, social-distancing measures effectively slowed disease transmission in many countries in Europe and Asia, but the same benefits have not been observed in some developing countries…

This paper considers a simple model where a social planner can influence the spread-intensity of an infection wave, and, consequently, also the economic activity and population health, through a single parameter. Population health is…

理论经济学 · 经济学 2020-05-18 Tommy Andersson , Albin Erlanson , Daniel Spiro , Robert Östling

We propose a simple SIR model in order to investigate the impact of various confinement strategies on a most virulent epidemic. Our approach is motivated by the current COVID-19 pandemic. The main hypothesis is the existence of two…

种群与进化 · 定量生物学 2020-12-30 G. Nakamura , B. Grammaticos , M. Badoual

Research in epidemiology often focusses on designing interventions that result in the number of infected individuals asymptotically approaching zero, without considering that this number may peak at high values during transients. Recent…

最优化与控制 · 数学 2020-03-24 Willem Esterhuizen , Tim Aschenbruck , Jean Lévine , Stefan Streif

In the context of epidemiology, policies for disease control are often devised through a mixture of intuition and brute-force, whereby the set of logically conceivable policies is narrowed down to a small family described by a few…

种群与进化 · 定量生物学 2021-10-04 Miguel Navascues , Costantino Budroni , Yelena Guryanova

Frequent emergence of communicable diseases has been a major concern worldwide. Lack of sufficient resources to mitigate the disease-burden makes the situation even more challenging for lower-income countries. Hence, strategy development…

种群与进化 · 定量生物学 2023-02-03 Biplab Maity , Swarnendu Banerjee , Abhishek Senapati , Joydev Chattopadhyay

Efficient personnel scheduling plays a significant role in matching workload demand in organizations. However, staff scheduling is sometimes affected by unexpected events, such as the COVID-19 pandemic, that disrupt regular operations.…

最优化与控制 · 数学 2023-01-10 Mansoor Davoodi , Ana Batista , Abhishek Senapati , Justin M. Calabrese

During the COVID-19 pandemic, case isolation emerged as a key non-pharmaceutical intervention in pandemic response. Its effectiveness hinges on the timing of isolation, which is often dictated by the onset of contagiousness. While…

种群与进化 · 定量生物学 2025-02-03 Jiahao Diao , Rebecca H. Chisholm , Nicholas Geard , James M. McCaw

Several non-pharmaceutical interventions have been proposed to control the spread of the COVID-19 pandemic. On the large scale, these empirical solutions, often associated with extended and complete lockdowns, attempt to minimize the costs…

物理与社会 · 物理学 2020-07-23 M. Serra , S. al-Mosleh , S. Ganga Prasath , V. Raju , S. Mantena , J. Chandra , S. Iams , L. Mahadevan

The World Health Organization (WHO) made the assessment that COVID-19 can be characterized as a pandemic on March 11, 2020. To the COVID-19 outbreak, there is no vaccination and no treatment. The only way to control the COVID-19 outbreak is…

种群与进化 · 定量生物学 2021-10-22 Samaherni M. Dias , Kurios I. P. de M. Queiroz , Allan de M. Martins

Group testing is an efficient method for testing a large population to detect infected individuals. In this paper, we consider an efficient adaptive two stage group testing scheme. Using a straightforward analysis, we characterize the…

统计方法学 · 统计学 2020-08-26 Arjun Kodialam

In epidemic or pandemic situations, resources for testing the infection status of individuals may be scarce. Although group testing can help to significantly increase testing capabilities, the (repeated) testing of entire populations can…

种群与进化 · 定量生物学 2021-10-29 Günther Koliander , Georg Pichler

The design of an efficient curing policy, able to stem an epidemic process at an affordable cost, has to account for the structure of the population contact network supporting the contagious process. Thus, we tackle the problem of…

最优化与控制 · 数学 2017-12-04 Stefania Ottaviano , Francesco De Pellegrini , Stefano Bonaccorsi , Piet Van Mieghem

We analyze the optimal control of disease prevention and treatment in a basic SIS model. We develop a simple macroeconomic setup in which the social planner determines how to optimally intervene, through income taxation, in order to…

理论经济学 · 经济学 2019-10-09 Davide La Torre , Tufail Malik , Simone Marsiglio

The COVID-19 pandemic left its unique mark on the 21st century as one of the most significant disasters in history, triggering governments all over the world to respond with a wide range of interventions. However, these restrictions come…

计算工程、金融与科学 · 计算机科学 2021-06-02 Assem Zhunis , Tung-Duong Mai , Sundong Kim

The implementation of public policies is crucial in controlling the spread of COVID-19. However, the effectiveness of different policies can vary across different aspects of epidemic containment. Identifying the most effective policies is…

应用统计 · 统计学 2024-08-27 Zihan Wang

When testing for infections, the standard method is to test each subject individually. If testing methodology is such that samples from multiple subjects can be efficiently combined and tested at once, yielding a positive results if any one…

统计方法学 · 统计学 2020-04-01 Anže Slosar