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This paper presents a randomization-based framework for estimating causal effects under interference between units, motivated by challenges that arise in analyzing experiments on social networks. The framework integrates three components:…

统计理论 · 数学 2018-06-21 Peter M. Aronow , Cyrus Samii

Cluster-randomized trials (CRTs) on fragile populations frequently encounter complex attrition problems where the reasons for missing outcomes can be heterogeneous, with participants who are known alive, known to have died, or with unknown…

统计方法学 · 统计学 2025-05-06 Guangyu Tong , Chenxi Li , Eric Velazquez , Michael O. Harhay , Fan Li

In a cluster-randomized experiment, treatment is assigned to clusters of individual units of interest--households, classrooms, villages, etc.--instead of the units themselves. The number of clusters sampled and the number of units sampled…

统计方法学 · 统计学 2020-02-20 Yeng Xiong , Michael J. Higgins

Patient-centered outcomes, such as quality of life and length of hospital stay, are the focus in a wide array of clinical studies. However, participants in randomized trials for elderly or critically and severely ill patient populations may…

统计方法学 · 统计学 2024-04-17 Dane Isenberg , Michael Harhay , Nandita Mitra , Fan Li

Suppose a researcher observes individuals within a county within a state. Given concerns about correlation across individuals, it is common to group observations into clusters and conduct inference treating observations across clusters as…

计量经济学 · 经济学 2022-01-24 Yong Cai

For randomized controlled trials (RCTs) with a single intervention being measured on multiple outcomes, researchers often apply a multiple testing procedure (such as Bonferroni or Benjamini-Hochberg) to adjust $p$-values. Such an adjustment…

统计方法学 · 统计学 2023-05-17 Kristen Hunter , Luke Miratrix , Kristin Porter

The spatial interaction between two or more classes of points may cause spatial clustering patterns such as segregation or association, which can be tested using a nearest neighbor contingency table (NNCT). A NNCT is constructed using the…

统计方法学 · 统计学 2008-07-29 Elvan Ceyhan

Estimating causal effects under interference is pertinent to many real-world settings. Recent work with low-order potential outcomes models uses a rollout design to obtain unbiased estimators that require no interference network…

统计方法学 · 统计学 2025-02-12 Mayleen Cortez-Rodriguez , Matthew Eichhorn , Christina Lee Yu

Stepped wedge cluster randomized trials (SW-CRTs) with binary outcomes are increasingly used in prevention and implementation studies. Marginal models represent a flexible tool for analyzing SW-CRTs with population-averaged interpretations,…

统计方法学 · 统计学 2021-01-05 Fan Li , Hengshi Yu , Paul J. Rathouz , Elizabeth L. Turner , John S. Preisser

Treatment effect estimands based on win statistics, including the win ratio, win odds, and win difference are increasingly popular targets for summarizing endpoints in clinical trials. Such win estimands offer an intuitive approach for…

统计方法学 · 统计学 2026-02-13 Kenneth M. Lee , Xi Fang , Fan Li , Michael O. Harhay

Power analyses are an important aspect of experimental design, because they help determine how experiments are implemented in practice. It is common to specify a desired level of power and compute the sample size necessary to obtain that…

统计方法学 · 统计学 2022-12-09 Zach Branson , Xinran Li , Peng Ding

Cluster randomized trials (CRTs) randomly assign an intervention to groups of individuals (e.g., clinics or communities) and measure outcomes on individuals in those groups. While offering many advantages, this experimental design…

Cluster randomized trials (CRTs) often enroll large numbers of participants, but due to logistical and fiscal challenges, only a subset of participants may be selected for measurement of certain outcomes, and those sampled may, purposely or…

统计方法学 · 统计学 2023-05-16 Joshua R. Nugent , Carina Marquez , Edwin D. Charlebois , Rachel Abbott , Laura B. Balzer

A first step when fitting multilevel models to continuous responses is to explore the degree of clustering in the data. Researchers fit variance-component models and then report the proportion of variation in the response that is due to…

统计方法学 · 统计学 2020-02-17 George Leckie , William Browne , Harvey Goldstein , Juan Merlo , Peter Austin

This article proposes a novel variance estimator for within-cluster resampling (WCR) and modified within-cluster resampling (MWCR) - two existing methods for analyzing longitudinal data. WCR is a simple but computationally intensive method,…

统计方法学 · 统计学 2019-12-02 Daniel Xu , Pamela Shaw , Ian Barnett

Randomized Controlled Trials (RCT) are the current gold standards to empirically measure the effect of a new drug. However, they may be of limited size and resorting to complementary non-randomized data, referred to as observational, is…

统计方法学 · 统计学 2025-06-11 Ahmed Boughdiri , Julie Josse , Erwan Scornet

We present an aggregation scheme that increases power in randomized controlled trials and quasi-experiments when the intervention possesses a robust and well-articulated theory of change. Longitudinal data analyzing interventions often…

统计方法学 · 统计学 2022-07-27 Timothy Lycurgus , Ben B. Hansen

We consider a potential outcomes model in which interference may be present between any two units but the extent of interference diminishes with spatial distance. The causal estimand is the global average treatment effect, which compares…

统计方法学 · 统计学 2022-09-16 Michael P. Leung

In this paper, numerical simulations of four-mode continuous-variable cluster states with different topologies in the framework of measurement-based quantum computation are presented. By utilizing the symplectic representation and…

量子物理 · 物理学 2026-04-28 Amin Ahadi , Saman Sarshar

Cluster randomized trials (CRTs) offer a practical alternative for addressing logistical challenges and ensuring feasibility in community health, education, and prevention studies, even though randomized controlled trials are considered the…

统计方法学 · 统计学 2025-10-30 Jooyeon Lee , M. S. , Evan Kwiatkowski , Ph. D