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Recent Covid-19 pandemic has demonstrated the need of efficient epidemic outbreak management. We study the optimal control problem of minimizing the fraction of infected population by applying vaccination and treatment control strategies,…

社会与信息网络 · 计算机科学 2021-12-07 Jagtap Kalyani Devendra , Kundan Kandhway

We consider the problem of controlling the propagation of an epidemic outbreak in an arbitrary contact network by distributing vaccination resources throughout the network. We analyze a networked version of the…

社会与信息网络 · 计算机科学 2013-03-19 Victor M. Preciado , Michael Zargham , Chinwendu Enyioha , Ali Jadbabaie , George Pappas

Epidemic risk assessment poses inherent challenges, with traditional approaches often failing to balance health outcomes and economic constraints. This paper presents a data-driven decision support tool that models epidemiological dynamics…

应用统计 · 统计学 2025-11-24 Chang Zhai , Ping Chen , Zhuo Jin , David Pitt

Optimal control of interdependent epidemics spreading over complex networks is a critical issue. We first establish a framework to capture the coupling between two epidemics, and then analyze the system's equilibrium states by categorizing…

系统与控制 · 计算机科学 2017-10-19 Juntao Chen , Rui Zhang , Quanyan Zhu

Testing is a crucial control mechanism for an epidemic outbreak because it enables the health authority to detect and isolate the infected cases, thereby limiting the disease transmission to susceptible people, when no effective treatment…

In the absence of drugs and vaccines, policymakers use non-pharmaceutical interventions such as social distancing to decrease rates of disease-causing contact, with the aim of reducing or delaying the epidemic peak. These measures carry…

种群与进化 · 定量生物学 2021-04-22 Dylan H. Morris , Fernando W. Rossine , Joshua B. Plotkin , Simon A. Levin

Testing is a crucial control mechanism in the beginning phase of an epidemic when the vaccines are not yet available. It enables the public health authority to detect and isolate the infected cases from the population, thereby limiting the…

To mitigate the impact of the pandemic, several measures include lockdowns, rapid vaccination programs, school closures, and economic stimulus. These interventions can have positive or unintended negative consequences. Current research to…

机器学习 · 计算机科学 2025-08-11 Gaurav Deshkar , Jayanta Kshirsagar , Harshal Hayatnagarkar , Janani Venugopalan

Modelling epidemics via classical population-based models suffers from shortcomings that so-called individual-based models are able to overcome, as they are able to take heterogeneity features into account, such as super-spreaders, and…

最优化与控制 · 数学 2022-05-16 C. Courtès , E. Franck , K. Lutz , L. Navoret , Y. Privat

We study an optimal control problem where the objective is to find the best vaccine allocation during an epidemic outbreak. The epidemic dynamics is described by an age-structured SIR model with nonlocal interactions. Both the infection and…

最优化与控制 · 数学 2026-05-19 Luís Almeida , Romain Ducasse , Elisa Paparelli

We propose a deterministic compartmental model of infectious disease which considers the test-kits as an important ingredient for the suppression and mitigation of epidemics. A rigorous simulation (with analytical argument) is provided to…

物理与社会 · 物理学 2021-07-28 Subrata Ghosh , Abhishek Senapati , Joydev Chattopadhyay , Chittaranjan Hens , Dibakar Ghosh

We study the optimal control problem of allocating campaigning resources over the campaign duration and degree classes in a social network. Information diffusion is modeled as a Susceptible-Infected epidemic and direct recruitment of…

社会与信息网络 · 计算机科学 2016-10-27 Kundan Kandhway , Joy Kuri

Network-based interventions against epidemic spread are most powerful when the full network structure is known. However, in practice, resource constraints require decisions to be made based on partial network information. We investigated…

应用统计 · 统计学 2019-03-19 Yingrui Yang , Ashley McKhann , Sixing Chen , Guy Harling , Jukka-Pekka Onnela

Controlling and understanding epidemic outbreaks has recently drawn great interest in a large spectrum of research communities. Vaccination is one of the most well-established and effective strategies in order to contain an epidemic. In the…

社会与信息网络 · 计算机科学 2023-05-29 Sourin Chatterjee , Ahad N. Zehmakan

Frequent emergence of communicable diseases has been a major concern worldwide. Lack of sufficient resources to mitigate the disease-burden makes the situation even more challenging for lower-income countries. Hence, strategy development…

种群与进化 · 定量生物学 2023-02-03 Biplab Maity , Swarnendu Banerjee , Abhishek Senapati , Joydev Chattopadhyay

Spreading processes represent a very efficient tool to investigate the structural properties of networks and the relative importance of their constituents, and have been widely used to this aim in static networks. Here we consider simple…

物理与社会 · 物理学 2013-09-11 Michele Starnini , Anna Machens , Ciro Cattuto , Alain Barrat , Romualdo Pastor Satorras

The design of an efficient curing policy, able to stem an epidemic process at an affordable cost, has to account for the structure of the population contact network supporting the contagious process. Thus, we tackle the problem of…

最优化与控制 · 数学 2017-12-04 Stefania Ottaviano , Francesco De Pellegrini , Stefano Bonaccorsi , Piet Van Mieghem

We investigate methods to vaccinate contact networks -- i.e. removing nodes in such a way that disease spreading is hindered as much as possible -- with respect to their cost-efficiency. Any real implementation of such protocols would come…

种群与进化 · 定量生物学 2017-11-01 Petter Holme , Nelly Litvak

This study explores the vaccine prioritization strategy to reduce the overall burden of the pandemic when the supply is limited. Existing methods conduct macro-level or simplified micro-level vaccine distribution by assuming the homogeneous…

种群与进化 · 定量生物学 2023-05-10 Lu Ling , Washim Uddin Mondal , Satish V , Ukkusuri

We study the optimal control problem of maximizing the spread of an information epidemic on a social network. Information propagation is modeled as a Susceptible-Infected (SI) process and the campaign budget is fixed. Direct recruitment and…

社会与信息网络 · 计算机科学 2016-02-16 Kundan Kandhway , Joy Kuri
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