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COVID-19 testing has become a standard approach for estimating prevalence which then assist in public health decision making to contain and mitigate the spread of the disease. The sampling designs used are often biased in that they do not…

统计方法学 · 统计学 2022-02-24 Daniel Andrés Díaz-Pachón , J Sunil Rao

During the COVID-19 pandemic, many institutions such as universities and workplaces implemented testing regimens with every member of some population tested longitudinally, and those testing positive isolated for some time. Although the…

统计方法学 · 统计学 2023-04-19 Patrick M. Schnell , Matthew Wascher , Grzegorz A. Rempala

Large-scale testing is considered key to assess the state of the current COVID-19 pandemic. Yet, the link between the reported case numbers and the true state of the pandemic remains elusive. We develop mathematical models based on…

应用统计 · 统计学 2021-02-04 Michel Besserve , Simon Buchholz , Bernhard Schölkopf

Countries officially record the number of COVID-19 cases based on medical tests of a subset of the population with unknown participation bias. For prevalence estimation, the official information is typically discarded and, instead, small…

统计方法学 · 统计学 2020-12-25 Stéphane Guerrier , Christoph Kuzmics , Maria-Pia Victoria-Feser

Sample pooling consists in combining samples from multiple individuals into a single pool that is then tested using a unique test-kit. A positive test means that at least one individual within the pool is infected. Here, we propose an…

定量方法 · 定量生物学 2021-03-18 Vincent Brault , Bastien Mallein , Jean-Francois Rupprecht

We propose a mathematical model based on probability theory to optimize COVID-19 testing by a multi-step batch testing approach with variable batch sizes. This model and simulation tool dramatically increase the efficiency and efficacy of…

统计方法学 · 统计学 2021-01-11 Hongshik Ahn , Haoran Jiang , Xiaolin Li

Gathering observational data for medical decision-making often involves uncertainties arising from both type I (false positive)and type II (false negative) errors. In this work, we develop a statistical model to study how medical…

应用统计 · 统计学 2025-10-21 Lucas Böttcher , Maria R. D'Orsogna , Tom Chou

The spread of COVID-19 makes it essential to investigate its prevalence. In such investigation research, as far as we know, the widely-used sampling methods didn't use the information sufficiently about the numbers of the previously…

应用统计 · 统计学 2022-01-04 Ze Liu , Siyu Yi , Jianghu , Dong , Min-Qian Liu , Yongdao Zhou

There are racial disparities in the COVID-19 test positivity rate, suggesting that minorities may be under-tested. Here, drawing on the literature on statistically assessing racial disparities in policing, we 1) illuminate a statistical…

应用统计 · 统计学 2020-11-03 Emma Pierson

In the last months, due to the emergency of Covid-19, questions related to the fact of belonging or not to a particular class of individuals (`infected or not infected'), after being tagged as `positive' or `negative' by a test, have never…

种群与进化 · 定量生物学 2020-11-23 Giulio D'Agostini , Alfredo Esposito

Testing individuals for pathogens can affect the spread of epidemics. Understanding how individual-level processes of sampling and reporting test results can affect community- or population-level spread is a dynamical modeling question. The…

种群与进化 · 定量生物学 2021-07-20 Ali Gharouni , F. M. Abdelmalek , David J. D. Earn , Jonathan Dushoff , Benjamin M. Bolker

The aim of the paper is to describe a model of the development of the Covid-19 contamination of the population of a country or a region. For this purpose a special branching process with two types of individuals is considered. This model is…

统计方法学 · 统计学 2020-04-03 Nikolay M. Yanev , Vessela K. Stoimenova , Dimitar V. Atanasov

Spatiotemporal modelling of infectious diseases such as COVID-19 involves using a variety of epidemiological metrics such as regional proportion of cases or regional positivity rates. Although observing their changes over time is critical…

There are many sources of data giving information about the number of SARS-CoV-2 infections in the population, but all have major drawbacks, including biases and delayed reporting. For example, the number of confirmed cases largely…

应用统计 · 统计学 2022-06-08 Nicholas J. Irons , Adrian E. Raftery

The interpretation of sampling data plays a crucial role in policy response to the spread of a disease during an epidemic, such as the COVID-19 epidemic of 2020. However, this is a non-trivial endeavor due to the complexity of real world…

种群与进化 · 定量生物学 2020-07-30 James D. Brunner , Nicholas Chia

A new method based on the rejection sampling for finding statistical tests is proposed. This method is conceptually intuitive, easy to implement, and applicable for arbitrary dimension. To illustrate its potential applicability, three…

统计方法学 · 统计学 2026-03-11 Markku Kuismin

Coronavirus case-count data has influenced government policies and drives most epidemiological forecasts. Limited testing is cited as the key driver behind minimal information on the COVID-19 pandemic. While expanded testing is laudable,…

统计方法学 · 统计学 2022-09-22 Walter Dempsey

When testing for a disease such as COVID-19, the standard method is individual testing: we take a sample from each individual and test these samples separately. An alternative is pooled testing (or "group testing"), where samples are mixed…

应用统计 · 统计学 2021-12-14 Matthew Aldridge , David Ellis

The correct evaluation of the reproductive number $R$ for COVID-19 -- which characterizes the average number of secondary cases generated by each typical primary case -- is central in the quantification of the potential scope of the…

应用统计 · 统计学 2021-04-15 Claire Donnat , Susan Holmes

The usual problem for group testing is this: For a given number of individuals and a given prevalence, how many tests T* are required to find every infected individual? In real life, however, the problem is usually different: For a given…

应用统计 · 统计学 2021-07-21 Matthew Aldridge
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