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An important component of every country's COVID-19 response is fast and efficient testing - to identify and isolate cases, as well as for early detection of local hotspots. For many countries, producing a sufficient number of tests has been…

统计方法学 · 统计学 2020-10-27 J. Batson , N. Bottman , Y. Cooper , F. Janda

The corona virus disease 2019 (COVID-19) caused by the novel corona virus has an exponential rate of infection. COVID-19 is particularly notorious as the onset of symptoms in infected patients are usually delayed and there exists a large…

统计方法学 · 统计学 2020-04-16 Lakshmi N. Theagarajan

The usual problem for group testing is this: For a given number of individuals and a given prevalence, how many tests T* are required to find every infected individual? In real life, however, the problem is usually different: For a given…

应用统计 · 统计学 2021-07-21 Matthew Aldridge

We consider the problem of identifying infected individuals in a population of size N. We introduce a group testing approach that uses significantly fewer than N tests when infection prevalence is low. The most common approach to group…

应用统计 · 统计学 2022-01-03 Paolo Bertolotti , Ali Jadbabaie

Testing is recommended for all close contacts of confirmed COVID-19 patients. However, existing group testing methods are oblivious to the circumstances of contagion provided by contact tracing. Here, we build upon a well-known…

应用统计 · 统计学 2021-07-01 Stratis Tsirtsis , Abir De , Lars Lorch , Manuel Gomez-Rodriguez

The group testing approach that achieves significant cost reduction over the individual testing approach has received a lot of interest lately for massive testing of COVID-19. Many studies simply assume samples mixed in a group are…

统计方法学 · 统计学 2021-11-12 Yi-Jheng Lin , Che-Hao Yu , Tzu-Hsuan Liu , Cheng-Shang Chang , Wen-Tsuen Chen

Repeated asymptomatic screening for SARS-CoV-2 promises to control spread of the virus but would require too many resources to implement at scale. Group testing is promising for screening more people with fewer test resources: multiple…

种群与进化 · 定量生物学 2020-11-18 Yifan Lin , Yuxuan Ren , Jingyuan Wan , Massey Cashore , Jiayue Wan , Yujia Zhang , Peter Frazier , Enlu Zhou

The outbreak of the global COVID-19 pandemic results in unprecedented demand for fast and efficient testing of large numbers of patients for the presence of SARS-CoV-2 coronavirus. Beside technical improvements of the cost and speed of…

统计方法学 · 统计学 2020-12-16 Andrzej Jaszkiewicz

In comparison with individual testing, group testing (also known as pooled testing) is more efficient in reducing the number of tests and potentially leading to tremendous cost reduction. As indicated in the recent article posted on the US…

种群与进化 · 定量生物学 2021-06-16 Yi-Jheng Lin , Che-Hao Yu , Tzu-Hsuan Liu , Cheng-Shang Chang , Wen-Tsuen Chen

Group testing is a screening strategy that involves dividing a population into several disjointed groups of subjects. In its simplest implementation, each group is tested with a single test in the first phase, while in the second phase only…

When testing for infections, the standard method is to test each subject individually. If testing methodology is such that samples from multiple subjects can be efficiently combined and tested at once, yielding a positive results if any one…

统计方法学 · 统计学 2020-04-01 Anže Slosar

We study Dorfman's classical group testing protocol in a novel setting where individual specimen statuses are modeled as exchangeable random variables. We are motivated by infectious disease screening. In that case, specimens which arrive…

应用统计 · 统计学 2024-02-28 Nicholas C. Landolfi , Sanjay Lall

The study in group testing aims to develop strategies to identify a small set of defective items among a large population using a few pooled tests. The established techniques have been highly beneficial in a broad spectrum of applications…

信息论 · 计算机科学 2025-01-23 Venkata Gandikota , Nikita Polyanskii , Haodong Yang

Sample pooling consists in combining samples from multiple individuals into a single pool that is then tested using a unique test-kit. A positive test means that at least one individual within the pool is infected. Here, we propose an…

定量方法 · 定量生物学 2021-03-18 Vincent Brault , Bastien Mallein , Jean-Francois Rupprecht

We show that combining a prediction model (based on neural networks), with a new method of test pooling (better than the original Dorfman method, and better than double-pooling) called 'Grid', we can reduce the number of Covid-19 tests by…

机器学习 · 计算机科学 2020-05-13 Tomer Cohen , Lior Finkelman , Gal Grimberg , Gadi Shenhar , Ofer Strichman , Yonatan Strichman , Stav Yeger

As humanity struggles to contain the global Covid-19 infection, prophylactic actions are grandly slowed down by the shortage of testing kits. Governments have taken several measures to work around this shortage: the FDA has become more…

Group testing is an efficient method for testing a large population to detect infected individuals. In this paper, we consider an efficient adaptive two stage group testing scheme. Using a straightforward analysis, we characterize the…

统计方法学 · 统计学 2020-08-26 Arjun Kodialam

When testing for a disease such as COVID-19, the standard method is individual testing: we take a sample from each individual and test these samples separately. An alternative is pooled testing (or "group testing"), where samples are mixed…

应用统计 · 统计学 2021-12-14 Matthew Aldridge , David Ellis

A key requirement in containing contagious diseases, such as the Coronavirus disease 2019 (COVID-19) pandemic, is the ability to efficiently carry out mass diagnosis over large populations. Some of the leading testing procedures, such as…

定量方法 · 定量生物学 2022-08-31 Amit Solomon , Alejandro Cohen , Nir Shlezinger , Yonina C. Eldar , Muriel Médard

In pandemics or epidemics, public health authorities need to rapidly test a large number of individuals, both to determine the line of treatment as well as to know the spread of infection to plan containment, mitigation and future…

其他定量生物学 · 定量生物学 2020-03-31 Tarun Jain , Bijendra Nath Jain
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