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Identifying genes underlying cancer development is critical to cancer biology and has important implications across prevention, diagnosis and treatment. Cancer sequencing studies aim at discovering genes with high frequencies of somatic…

应用统计 · 统计学 2013-12-09 Jie Ding , Lorenzo Trippa , Xiaogang Zhong , Giovanni Parmigiani

Comparing directed acyclic graphs is essential in various fields such as healthcare, social media, finance, biology, and marketing. DAGs often result from contagion processes over networks, including information spreading, retweet activity,…

人机交互 · 计算机科学 2024-08-31 Kathrin Guckes , Marc Schäpers , Margit Pohl , Andreas Kerren , Tatiana von Landesberger

We study one particular type of multivariate spatial autoregression (MSAR) model with diverging dimensions in both responses and covariates. This makes the usual MSAR models no longer applicable due to the high computational cost. To…

统计方法学 · 统计学 2025-09-03 Jiaxin Shi , Xuening Zhu , Jing Zhou , Baichen Yu , Hansheng Wang

Computer-aided diagnosis (CAD), a vibrant medical imaging research field, is expanding quickly. Because errors in medical diagnostic systems might lead to seriously misleading medical treatments, major efforts have been made in recent years…

机器学习 · 计算机科学 2023-08-04 Farzaneh Tajidini , Mohammad-Javad Kheiri

Understanding the relationships between different properties of data, such as whether a connectome or genome has information about disease status, is becoming increasingly important in modern biological datasets. While existing approaches…

This paper proposes to learn Multi-task, Multi-modal Direct Acyclic Graphs (MM-DAGs), which are commonly observed in complex systems, e.g., traffic, manufacturing, and weather systems, whose variables are multi-modal with scalars, vectors,…

机器学习 · 统计学 2023-06-06 Tian Lan , Ziyue Li , Zhishuai Li , Lei Bai , Man Li , Fugee Tsung , Wolfgang Ketter , Rui Zhao , Chen Zhang

In epidemiological disease mapping one aims to estimate the spatio-temporal pattern in disease risk and identify high-risk clusters, allowing health interventions to be appropriately targeted. Bayesian spatio-temporal models are used to…

统计方法学 · 统计学 2014-11-11 Duncan Lee , Andrew Lawson

Directed acyclic graphs (DAGs) are a popular framework to express multivariate probability distributions. Acyclic directed mixed graphs (ADMGs) are generalizations of DAGs that can succinctly capture much richer sets of conditional…

机器学习 · 统计学 2010-09-01 Ricardo Silva , Charles Blundell , Yee Whye Teh

Many scientific applications involve mixed spatially indexed outcomes of heterogeneous types that are driven by shared latent mechanisms. Modeling such data is challenging due to complex, nonlinear, and potentially nonstationary spatial…

统计方法学 · 统计学 2026-03-10 Yeseul Jeon , Kyeong Eun Lee , Joon Jin Song

Convolution is spatially-symmetric, i.e., the visual features are independent of its position in the image, which limits its ability to utilize contextual cues for visual recognition. This paper addresses this issue by introducing a…

计算机视觉与模式识别 · 计算机科学 2018-04-04 Yan Wang , Lingxi Xie , Siyuan Qiao , Ya Zhang , Wenjun Zhang , Alan L. Yuille

Spatial relationships in multi-species data can indicate and affect system outcomes and behaviors, ranging from disease progression in cancer to coral reef resilience in ecology; therefore, quantifying these relationships is an important…

Unmeasured spatial confounding complicates exposure effect estimation in environmental health studies. This problem is exacerbated in studies with multiple health outcomes and environmental exposure variables, as the source and magnitude of…

Identifying disease-indicative genes is critical for deciphering disease mechanisms and has attracted significant interest in biomedical research. Spatial transcriptomics offers unprecedented insights for the detection of disease-specific…

统计方法学 · 统计学 2024-09-05 Qicheng Zhao , Qihuang Zhang

This work aims to learn the directed acyclic graph (DAG) that captures the instantaneous dependencies underlying a multivariate time series. The observed data follow a linear structural vector autoregressive model (SVARM) with both…

信号处理 · 电气工程与系统科学 2025-12-09 Samuel Rey , Gonzalo Mateos

Spatial correlation in areal unit count data is typically modelled by a set of random effects that are assigned a conditional autoregressive (CAR) prior distribution. The spatial correlation structure implied by this model depends on a…

统计方法学 · 统计学 2020-10-22 Duncan Lee , Kitty Meeks

Health surveys provide valuable information for monitoring population health, identifying risk factors and informing public health policies. Most of the questions included are coded as ordinal variables and organized into thematic blocks.…

Bayesian networks are a widely-used class of probabilistic graphical models capable of representing symmetric conditional independence between variables of interest using the topology of the underlying graph. For categorical variables, they…

机器学习 · 统计学 2022-10-07 Gherardo Varando , Federico Carli , Manuele Leonelli

Maps have long been been used to visualise estimates of spatial variables, in particular disease burden and risk. Predictions made using a geostatistical model have uncertainty that typically varies spatially. However, this uncertainty is…

应用统计 · 统计学 2020-05-26 Aimee R Taylor , James A Watson , Caroline O Buckee

Directed acyclic graphs (DAGs) and associated probability models are widely used to model neural connectivity and communication channels. In many experiments, data are collected from multiple subjects whose connectivities may differ but are…

统计方法学 · 统计学 2014-11-17 Chris J. Oates , Lilia Carneiro da Costa , Tom Nichols

Medical image generation is pivotal in applications like data augmentation for low-resource clinical tasks and privacy-preserving data sharing. However, developing a scalable generative backbone for medical imaging requires architectural…

计算机视觉与模式识别 · 计算机科学 2026-02-24 Zhicheng He , Yunpeng Zhao , Junde Wu , Ziwei Niu , Zijun Li , Bohan Li , Lanfen Lin , Yueming Jin