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The multiple futile cycle is a phosphorylation system in which a molecular substrate might be phosphorylated sequentially n times by means of an enzymatic mechanism. The system has been studied mathematically using reaction network theory…

分子网络 · 定量生物学 2020-10-28 Elisenda Feliu , Alan D. Rendall , Carsten Wiuf

Dynamic phenomena in social and biological sciences can often be modeled by employing reaction-diffusion equations. When addressing the control of these modes, from a mathematical viewpoint one of the main challenges is that, because of the…

最优化与控制 · 数学 2020-06-02 Domènec Ruiz-Balet , Enrique Zuazua

Stochastic models of reaction networks are becoming increasingly important in Systems Biology. In these models, the dynamics is generally represented by a continuous-time Markov chain whose states denote the copy-numbers of the constituent…

概率论 · 数学 2018-02-12 Ankit Gupta , Mustafa Khammash

We find an exact series solution for the steady-state probability distribution of a harmonically trapped active Brownian particle in two dimensions, in the presence of translational diffusion. This series solution allows us to efficiently…

统计力学 · 物理学 2020-03-04 Kanaya Malakar , Arghya Das , Anupam Kundu , K. Vijay Kumar , Abhishek Dhar

Networks of model neurons with balanced recurrent excitation and inhibition produce irregular and asynchronous spiking activity. We extend the analysis of balanced networks to include the known dependence of connection probability on the…

神经元与认知 · 定量生物学 2014-06-02 Robert Rosenbaum , Brent Doiron

This article is concerned with stability analysis and stabilization of randomly switched nonlinear systems. These systems may be regarded as piecewise deterministic stochastic systems: the discrete switches are triggered by a stochastic…

最优化与控制 · 数学 2010-09-08 Debasish Chatterjee , Daniel Liberzon

We study reaction zones in three different versions of the A+B->0 system. For a steady state formed by opposing currents of A and B particles we derive scaling behavior via renormalization group analysis. By use of a previously developed…

凝聚态物理 · 物理学 2009-10-22 Benjamin P. Lee , John Cardy

We improve the upper bound for the maximum possible number of stable matchings among $n$ jobs and $n$ applicants from $131072^n+O(1)$ to $3.55^n+O(1)$. To establish this bound, we state a novel formulation of a certain entropy bound that is…

组合数学 · 数学 2021-06-07 Cory Palmer , Dömötör Pálvölgyi

We consider a decentralised multi-access algorithm, motivated primarily by the control of transmissions in a wireless network. For a finite single-hop network with arbitrary interference constraints we prove stochastic stability under the…

信息论 · 计算机科学 2019-06-03 Seva Shneer , Alexander Stolyar

Two mechanisms for nonlinear mode saturation of the r-mode in neutron stars have been suggested: the parametric instability mechanism involving a small number of modes and the formation of a nearly continuous Kolmogorov-type cascade. Using…

广义相对论与量子宇宙学 · 物理学 2016-08-31 Jeandrew Brink , Saul A. Teukolsky , Ira Wasserman

The fluid model has proven to be one of the most effective tools for the analysis of stochastic queueing networks, specifically for the analysis of stability. It is known that stability of a fluid model implies positive (Harris) recurrence…

概率论 · 数学 2007-05-23 David Gamarnik , John Hasenbein

The information that a pattern of firing in the output layer of a feedforward network of threshold-linear neurons conveys about the network's inputs is considered. A replica-symmetric solution is found to be stable for all but small amounts…

无序系统与神经网络 · 物理学 2009-10-30 Simon Schultz , Alessandro Treves

We consider the existence of multiple positive solutions to the nonlinear Schr\"odinger systems sets on $H^1(\mathbb{R}^N) \times H^1(\mathbb{R}^N)$, \[ \left\{ \begin{aligned} -\Delta u_1 &= \lambda_1 u_1 + \mu_1 |u_1|^{p_1 -2}u_1 + \beta…

偏微分方程分析 · 数学 2018-05-09 Tianxiang Gou , Louis Jeanjean

Numerical solution of the chemical master equation for stochastic reaction networks typically suffers from the state space explosion problem due to the curse of dimensionality and from stiffness due to multiple time scales. The dimension of…

分子网络 · 定量生物学 2019-07-25 Linar Mikeev , Werner Sandmann

We study a stochastic system of interacting neurons and its metastable properties. The system consists of $N$ neurons, each spiking randomly with rate depending on its membrane potential. At its spiking time, the neuron potential is reset…

概率论 · 数学 2020-12-09 Eva Löcherbach , Pierre Monmarché

In a recent paper it was shown that, for chemical reaction networks possessing a subtle structural property called concordance, dynamical behavior of a very circumscribed (and largely stable) kind is enforced, so long as the kinetics lies…

分子网络 · 定量生物学 2012-04-26 Guy Shinar , Martin Feinberg

We consider stochastically modeled reaction networks and prove that if a constant solution to the Kolmogorov forward equation decays fast enough relatively to the transition rates, then the model is non-explosive. In particular, complex…

We consider the dynamics of diffusing particles in one space dimension with annihilation on collision and nucleation (creation of particles) with constant probability per unit time and length. The cases of nucleation of single particles and…

统计力学 · 物理学 2009-11-07 S. Habib , K. Lindenberg , G. Lythe , C. Molina-Paris

We have previously discussed the one-dimensional multitrap system of finite range and found the somewhat unexpected result that the larger is the number of imperfect traps the higher is the transmission through them. We discuss in this work…

经典物理 · 物理学 2009-11-07 D. Bar

We study networks of interacting queues governed by utility-maximising service-rate allocations in both discrete and continuous time. For {\em finite} networks we establish stability and some steady-state moment bounds under natural…

概率论 · 数学 2019-08-21 Seva Shneer , Alexander Stolyar