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Excess hazard modeling is one of the main tools in population-based cancer survival research. Indeed, this setting allows for direct modeling of the survival due to cancer even in the absence of reliable information on the cause of death,…

统计方法学 · 统计学 2022-04-12 A. Eletti , G. Marra , M. Quaresma , R. Radice , F. J. Rubio

Lung and Colon cancer are one of the leading causes of mortality and morbidity in adults. Histopathological diagnosis is one of the key components to discern cancer type. The aim of the present research is to propose a computer aided…

图像与视频处理 · 电气工程与系统科学 2020-09-09 Sanidhya Mangal , Aanchal Chaurasia , Ayush Khajanchi

Modern deep neural networks have achieved great successes in medical image analysis. However, the features captured by convolutional neural networks (CNNs) or Transformers tend to be optimized for pixel intensities and neglect key…

计算机视觉与模式识别 · 计算机科学 2023-11-30 Yaopeng Peng , Hongxiao Wang , Milan Sonka , Danny Z. Chen

Topological Data Analysis is a relatively new field of study that uses topological invariants to study the shape of data. We analyze a dataset provided by the Centers for Disease Control and Prevention (CDC) using persistent homology and…

代数拓扑 · 数学 2025-10-20 Megan Fairchild , Matthew Lemoine

Strong experimental evidence has indicated that tumor growth belongs to the molecular beam epitaxy universality class. This type of growth is characterized by the constraint of cell proliferation to the tumor border, and surface diffusion…

定量方法 · 定量生物学 2009-11-13 Carlos Escudero

Survival prediction is a crucial task associated with cancer diagnosis and treatment planning. This paper presents a novel approach to survival prediction by harnessing comprehensive information from CT and PET scans, along with associated…

图像与视频处理 · 电气工程与系统科学 2024-10-01 Aiman Farooq , Deepak Mishra , Santanu Chaudhury

Persistent Homology is a fairly new branch of Computational Topology which combines geometry and topology for an effective shape description of use in Pattern Recognition. In particular it registers through "Betti Numbers" the presence of…

定量方法 · 定量生物学 2016-06-01 Massimo Ferri , Ivan Tomba , Andrea Visotti , Ignazio Stanganelli

Deep learning based analysis of histopathology images shows promise in advancing the understanding of tumor progression, tumor micro-environment, and their underpinning biological processes. So far, these approaches have focused on…

图像与视频处理 · 电气工程与系统科学 2021-08-29 Adalberto Claudio Quiros , Nicolas Coudray , Anna Yeaton , Wisuwat Sunhem , Roderick Murray-Smith , Aristotelis Tsirigos , Ke Yuan

With nearly one million new cases diagnosed worldwide in 2020, head \& neck cancer is a deadly and common malignity. There are challenges to decision making and treatment of such cancer, due to lesions in multiple locations and outcome…

图像与视频处理 · 电气工程与系统科学 2023-05-17 Angel Victor Juanco Muller , Joao F. C. Mota , Keith A. Goatman , Corne Hoogendoorn

Tumor growth is a complex process characterized by uncontrolled cell proliferation and invasion of neighboring tissues. The understanding of these phenomena is of vital importance to establish appropriate diagnosis and therapeutic strategy…

组织与器官 · 定量生物学 2019-10-23 Miguel Martín-Landrove , Francisco Torres-Hoyos , Antonio Rueda-Toicen

Lung cancer is one of the death threatening diseases among human beings. Early and accurate detection of lung cancer can increase the survival rate from lung cancer. Computed Tomography (CT) images are commonly used for detecting the lung…

机器学习 · 统计学 2019-11-26 Md Rashidul Hasan , Muntasir Al Kabir

Stochastic resonance induced by external factor is considering to investigate the complex dynamics of tumor. The surrounding environment and the treatment effects on the tumor growth are considered as additive and multiplicative noises in…

细胞行为 · 定量生物学 2017-07-18 Najmeh Sadat Mirian

Cancer is a disease of cellular regulation, often initiated by genetic mutation within cells, and leading to a heterogeneous cell population within tissues. In the competition for nutrients and growth space within the tumors the phenotype…

种群与进化 · 定量生物学 2017-08-08 András Szabó , Roeland M. H. Merks

Unstable dynamics characterizes the evolution of most solid tumors. Because of an increased failure of maintaining genome integrity, a cumulative increase in the levels of gene mutation and loss is observed. Previous work suggests that…

生物物理 · 物理学 2015-06-18 Daniel R. Amor , Ricard V. Solé

Different cell types aggregate and sort into hierarchical architectures during the formation of animal tissues. The resulting spatial organization depends (in part) on the strength of adhesion of one cell type to itself relative to other…

定量方法 · 定量生物学 2023-08-02 Dhananjay Bhaskar , William Y. Zhang , Alexandria Volkening , Björn Sandstede , Ian Y. Wong

The field of mathematical morphology offers well-studied techniques for image processing. In this work, we view morphological operations through the lens of persistent homology, a tool at the heart of the field of topological data analysis.…

计算几何 · 计算机科学 2021-03-25 Yu-Min Chung , Sarah Day , Chuan-Shen Hu

Breast cancer is a health problem that affects mainly the female population. An early detection increases the chances of effective treatment, improving the prognosis of the disease. In this regard, computational tools have been proposed to…

计算机视觉与模式识别 · 计算机科学 2022-03-01 Steve Tsham Mpinda Ataky , Alessandro Lameiras Koerich

In topological data analysis, persistent homology characterizes robust topological features in data and it has a summary representation, called a persistence diagram. Statistical research for persistence diagrams have been actively…

代数拓扑 · 数学 2018-10-29 Genki Kusano

In this work we use the persistent homology method, a technique in topological data analysis (TDA), to extract essential topological features from the data space and combine them with deep learning features for classification tasks. In TDA,…

计算机视觉与模式识别 · 计算机科学 2023-11-14 Mariana Dória Prata Lima , Gilson Antonio Giraldi , Gastão Florêncio Miranda Junior

We apply persistent homology, the main method in topological data analysis, to the study of demographic data. Persistence diagrams efficiently summarize information about clusters or peaks in a region's demographic data. To illustrate how…

代数拓扑 · 数学 2023-10-13 Jakini A. Kauba , Thomas Weighill