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This paper presents a detailed mathematical investigation into the dynamics of COVID-19 infections through extended Susceptible-Infected-Recovered (SIR) and Susceptible-Exposed-Infected-Recovered (SEIR) epidemiological models. By…

种群与进化 · 定量生物学 2025-05-21 Caleb Traxler , Minh Ton , Nameer Ahmed , Sasha Prostota , Annie Cheng

The outbreak and propagation of COVID-19 have posed a considerable challenge to modern society. In particular, the different restrictive actions taken by governments to prevent the spread of the virus have changed the way humans interact…

Determinants of COVID-19 clinical severity are commonly assessed by transverse or longitudinal studies of the fatality counts. However, the fatality counts depend both on disease clinical severity and transmissibility, as more infected also…

种群与进化 · 定量生物学 2021-09-02 Sofija Markovic , Andjela Rodic , Igor Salom , Ognjen Milicevic , Magdalena Djordjevic , Marko Djordjevic

We make a retrospective review on various control measures taken by 127 countries/territories during the first wave of COVID-19 pandemic until July 7, 2020, and evaluate their impacts on the epidemic dynamics quantitatively. The SEIR-QD…

种群与进化 · 定量生物学 2023-09-25 Dongyan Zhang , Wuyue Yang , Wanqi Wen , Liangrong Peng , Changjingn Zhuge , Liu Hong

COVID-19 has resulted in a public health global crisis. The pandemic control necessitates epidemic models that capture the trends and impacts on infectious individuals. Many exciting models can implement this but they lack practical…

计算机与社会 · 计算机科学 2021-04-13 Ou Deng , Kiichi Tago , Qun Jin

In this paper, we introduce a novel modeling framework for incorporating fear of infection and frustration with social distancing into disease dynamics. We show that the resulting SEIR behavior-perception model has three principal modes of…

种群与进化 · 定量生物学 2020-08-14 Matthew D. Johnston , Bruce Pell

We model further development of the COVID-19 epidemic in the UK given the current data and assuming different scenarios of handling the epidemic. In this research, we further extend the stochastic model suggested in \cite{us} and…

种群与进化 · 定量生物学 2020-04-10 Anatoly Zhigljavsky , Roger Whitaker , Ivan Fesenko , Kobi Kremnizer , Jack Noonan

We recently described a dynamic causal model of a COVID-19 outbreak within a single region. Here, we combine several of these (epidemic) models to create a (pandemic) model of viral spread among regions. Our focus is on a second wave of new…

The novel COVID-19 pandemic is a current, major global health threat. Up till now, there is no fully approved pharmacological treatment or a vaccine. In this study, simple mathematical models were employed to examine the dynamics of…

物理与社会 · 物理学 2020-12-25 Ahmed S. Elgazzar

There is a continuing debate on relative benefits of various mitigation and suppression strategies aimed to control the spread of COVID-19. Here we report the results of agent-based modelling using a fine-grained computational simulation of…

种群与进化 · 定量生物学 2020-11-12 Sheryl L. Chang , Nathan Harding , Cameron Zachreson , Oliver M. Cliff , Mikhail Prokopenko

We consider the transmission dynamics of COVID-19 which is characterized by two distinct features. One is the existence of asymptomatic carriers which is a hidden variable in the problem. The other is the issue of latency which means that…

种群与进化 · 定量生物学 2020-12-07 Akshay Pal , Jayanta K Bhattacharjee

We consider here an extended SIR model, including several features of the recent COVID-19 outbreak: in particular the infected and recovered individuals can either be detected (+) or undetected (-) and we also integrate an intensive care…

种群与进化 · 定量生物学 2020-05-25 Arthur Charpentier , Romuald Elie , Mathieu Laurière , Viet Chi Tran

The Covid-19 pandemic has taken millions of lives, demonstrating the tragedy and disruption of respiratory diseases, and how difficult they can be to manage. However, there is still significant debate in the scientific community as to which…

The dynamics of epidemics depend on how people's behavior changes during an outbreak. At the beginning of the epidemic, people do not know about the virus, then, after the outbreak of epidemics and alarm, they begin to comply with the…

物理与社会 · 物理学 2021-11-29 I. A. Kastalskiy , E. V. Pankratova , E. M. Mirkes , V. B. Kazantsev , A. N. Gorban

Two stochastic models are proposed to describe the evolution of the COVID-19 pandemic. In the first model the population is partitioned into four compartments: susceptible $S$, infected $I$, removed $R$ and dead people $D$. In order to have…

种群与进化 · 定量生物学 2021-09-16 Fabiana Calleri , Giovanni Nastasi , Vittorio Romano

Although modeling studies are focused on the control of SIR-based systems describing epidemic data sets (particularly the COVID-19), few of them present a formal dynamic characterization in terms of equilibrium sets and stability. Such…

最优化与控制 · 数学 2021-06-03 A. H. González , A. L. Anderson , A. Ferramosca , E. A. Hernandez-Vargas

We present a System Dynamics (SD) model of the Covid-19 pandemic spread in India. The detailed age-structured compartment-based model endogenously captures various disease transmission pathways, expanding significantly from the standard…

种群与进化 · 定量生物学 2020-04-21 Jayendran Venkateswaran , Om Damani

Pandemic control measures like lock-down, restrictions on restaurants and gatherings, social-distancing have shown to be effective in curtailing the spread of COVID-19. However, their sustained enforcement has negative economic effects. To…

The Susceptible-Exposed-Infected-Recovered (SEIR) epidemiological model is one of the standard models of disease spreading. Here we analyse an extended SEIR model that accounts for asymptomatic carriers, believed to play an important role…

种群与进化 · 定量生物学 2021-01-26 Arghya Das , Abhishek Dhar , Srashti Goyal , Anupam Kundu , Saurav Pandey

The spread of diseases has been studied for many years, but it receives a particular focus recently due to the outbreak and spread of COVID-19. Studies show that the spread of COVID-19 can be characterized by the…

机器学习 · 计算机科学 2022-04-12 Xiaoxu Zhong , Yukun Ye