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Reciprocity, or the tendency of individuals to mirror behavior, is a key measure that describes information exchange in a social network. Users in social networks tend to engage in different levels of reciprocal behavior. Differences in…

机器学习 · 统计学 2023-08-22 Daniel Cirkovic , Tiandong Wang

The recent discovery of universal principles underlying many complex networks occurring across a wide range of length scales in the biological world has spurred physicists in trying to understand such features using techniques from…

生物物理 · 物理学 2015-05-13 Sitabhra Sinha

Robustness, the insensitivity of some of a biological system's functionalities to a set of distinct conditions, is intimately linked to fitness. Recent studies suggest that it may also play a vital role in enabling the evolution of species.…

适应与自组织系统 · 物理学 2011-12-15 James M Whitacre , Axel Bender

We investigate the dissipative mechanisms exhibited by creased material sheets when subjected to mechanical loading, which comes in the form of plasticity and relaxation phenomena within the creases. After demonstrating that plasticity…

软凝聚态物质 · 物理学 2020-09-30 Théo Jules , Frédéric Lechenault , Mokhtar Adda-Bedia

The functioning of many biochemical networks is often robust -- remarkably stable under changes in external conditions and internal reaction parameters. Much recent work on robustness and evolvability has focused on the structure of neutral…

定量方法 · 定量生物学 2011-03-15 Bryan C. Daniels , Yan-Jiun Chen , James P. Sethna , Ryan N. Gutenkunst , Christopher R. Myers

Modern ecology has re-emphasized the need for a quantitative understanding of the original 'survival of the fittest theme' based on analyzis of the intricate trade-offs between competing evolutionary strategies that characterize the…

种群与进化 · 定量生物学 2015-06-16 Jacopo Grilli , Samir Suweis , Amos Maritan

In this paper we study a rate-independent system for the propagation of damage and plasticity. To construct solutions we resort to approximation in terms of viscous evolutions, where viscosity affects both damage and plasticity with the…

偏微分方程分析 · 数学 2024-09-02 Vito Crismale , Giuliano Lazzaroni , Riccarda Rossi

Artificial neural networks (ANNs) are typically confined to accomplishing pre-defined tasks by learning a set of static parameters. In contrast, biological neural networks (BNNs) can adapt to various new tasks by continually updating the…

人工智能 · 计算机科学 2022-09-20 Fan Wang , Hao Tian , Haoyi Xiong , Hua Wu , Jie Fu , Yang Cao , Yu Kang , Haifeng Wang

Mutualistic networks are formed when the interactions between two classes of species are mutually beneficial. They are important examples of cooperation shaped by evolution. Mutualism between animals and plants plays a key role in the…

种群与进化 · 定量生物学 2013-08-23 Samir Suweis , Filippo Simini , Jayanth R. Banavar , Amos Maritan

Living organisms must respond to environmental changes. Generally, accurate and rapid responses are provided by simple, unidirectional networks that connect inputs with outputs. Besides accuracy and speed, biological responses should also…

分子网络 · 定量生物学 2021-09-01 Masayo Inoue , Kunihiko Kaneko

Homeostasis of protein concentrations in cells is crucial for their proper functioning, and this requires concentrations (at their steady-state levels) to be stable to fluctuations. Since gene expression is regulated by proteins such as…

生物物理 · 物理学 2020-11-10 Yipei Guo , Ariel Amir

All types of networks arise as intricate combinations of dyadic building blocks formed by pairs of vertices. In directed networks, the dyadic patterns are entirely determined by reciprocity, i.e. the tendency to form, or to avoid, mutual…

数据分析、统计与概率 · 物理学 2014-01-14 Tiziano Squartini , Francesco Picciolo , Franco Ruzzenenti , Diego Garlaschelli

The evolutionary origins of structural features in reconstructed gene-regulatory networks (GRNs) remain poorly understood, especially given the random aspects of gene expression. Here, we extend a classical model of GRN evolution to allow a…

种群与进化 · 定量生物学 2026-04-30 Leonardo Ivan Estrella Dzib , James Holehouse

Evolutionary dynamics is often viewed as a subtle process of change accumulation that causes a divergence among organisms and their genomes. However, this interpretation is an inheritance of a gradualistic view that has been challenged at…

种群与进化 · 定量生物学 2018-07-27 Jacobo Aguirre , Pablo Catalán , José A. Cuesta , Susanna Manrubia

Control of the living cell functions with remarkable reliability despite the stochastic nature of the underlying molecular networks -- a property presumably optimized by biological evolution. We here ask to what extent the property of a…

分子网络 · 定量生物学 2009-11-13 Stefan Braunewell , Stefan Bornholdt

Based on a non-equilibrium mechanism for spatial pattern formation we study how position information can be controlled by locally coupled discrete dynamical networks, similar to gene regulation networks of cells in a developing…

分子网络 · 定量生物学 2009-08-26 Thimo Rohlf , Stefan Bornholdt

Genetic regulation is a key component in development, but a clear understanding of the structure and dynamics of genetic networks is not yet at hand. In this paper we investigate these properties within an artificial genome model originally…

分子网络 · 定量生物学 2009-08-26 Thimo Rohlf , Christopher R. Winkler

Synaptic plasticity typically produces heavy-tailed distributions of synaptic strengths, consisting of a few strong connections among many weaker ones. Meanwhile, structural plasticity relies on distinct signaling cascades to reshape…

神经元与认知 · 定量生物学 2026-01-06 Jia Li , Cees van Leeuwen , Roman Bauer , Ilias Rentzeperis

The role of species interactions in controlling the interplay between the stability of an ecosystem and its biodiversity is still not well understood. The ability of ecological communities to recover after a small perturbation of the…

Diverse biological networks exhibit universal features distinguished from those of random networks, calling much attention to their origins and implications. Here we propose a minimal evolution model of Boolean regulatory networks, which…

分子网络 · 定量生物学 2014-11-26 Deok-Sun Lee