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Cochran's $Q$ statistic is routinely used for testing heterogeneity in meta-analysis. Its expected value is also used for estimation of between-study variance $\tau^2$. Cochran's $Q$, or $Q_{IV}$, uses estimated inverse-variance weights…

统计方法学 · 统计学 2021-03-08 Ilyas Bakbergenuly , David C. Hoaglin , Elena Kulinskaya

Cochran's $Q$ statistic is routinely used for testing heterogeneity in meta-analysis. Its expected value (under an incorrect null distribution) is part of several popular estimators of the between-study variance, $\tau^2$. Those…

统计方法学 · 统计学 2023-04-11 Elena Kulinskaya , David C. Hoaglin

A number of popular estimators of the between-study variance, $\tau^2$, are based on the Cochran's $Q$ statistic for testing heterogeneity in meta analysis. We introduce new point and interval estimators of $\tau^2$ for log-odds-ratio.…

统计方法学 · 统计学 2022-08-02 Elena Kulinskaya , David C. Hoaglin

Methods for random-effects meta-analysis require an estimate of the between-study variance, $\tau^2$. The performance of estimators of $\tau^2$ (measured by bias and coverage) affects their usefulness in assessing heterogeneity of…

统计方法学 · 统计学 2019-03-05 Ilyas Bakbergenuly , David C. Hoaglin , Elena Kulinskaya

Methods for random-effects meta-analysis require an estimate of the between-study variance, $\tau^2$. The performance of estimators of $\tau^2$ (measured by bias and coverage) affects their usefulness in assessing heterogeneity of…

统计方法学 · 统计学 2019-04-04 Ilyas Bakbergenuly , David C. Hoaglin , Elena Kulinskaya

Random-effects meta-analysis requires an estimate of the between-study variance, $\tau^2$. We study methods of estimation of $\tau^2$ and its confidence interval in meta-analysis of odds ratio, and also the performance of related estimators…

统计方法学 · 统计学 2019-02-20 Ilyas Bakbergenuly , David C. Hoaglin , Elena Kulinskaya

When the individual studies assembled for a meta-analysis report means ($\mu_C$, $\mu_T$) for their treatment (T) and control (C) arms, but those data are on different scales or come from different instruments, the customary measure of…

统计方法学 · 统计学 2023-04-18 Elena Kulinskaya , David C. Hoaglin

Quantifying the heterogeneity is an important issue in meta-analysis, and among the existing measures, the $I^2$ statistic is most commonly used. In this paper, we first illustrate with a simple example that the $I^2$ statistic is heavily…

统计方法学 · 统计学 2025-06-10 Ke Yang , Enxuan Lin , Wangli Xu , Liping Zhu , Tiejun Tong

Meta-analysis seeks to combine the results of several experiments in order to improve the accuracy of decisions. It is common to use a test for homogeneity to determine if the results of the several experiments are sufficiently similar to…

统计方法学 · 统计学 2009-08-01 Elena Kulinskaya , Michael B. Dollinger , Kirsten Bjørkestøl

We consider a three-level meta-analysis of standardized mean differences. The standard method of estimation uses inverse-variance weights and REML/PL estimation of variance components for the random effects. We introduce new moment-based…

统计方法学 · 统计学 2024-11-05 Elena Kulinskaya , David C. Hoaglin

Quantifying the heterogeneity is an important issue in meta-analysis, and among the existing measures, the $I^2$ statistic is the most commonly used measure in the literature. In this paper, we show that the $I^2$ statistic was, in fact,…

统计方法学 · 统计学 2024-03-28 Ke Yang , Enxuan Lin , Tiejun Tong

Methods for random-effects meta-analysis require an estimate of the between-study variance, $\tau^2$. The performance of estimators of $\tau^2$ (measured by bias and coverage) affects their usefulness in assessing heterogeneity of…

统计方法学 · 统计学 2019-07-09 Ilyas Bakbergenuly , David C. Hoaglin , Elena Kulinskaya

We consider the setting of an aggregate data meta-analysis of a continuous outcome of interest. When the distribution of the outcome is skewed, it is often the case that some primary studies report the sample mean and standard deviation of…

In classical statistics and distribution testing, it is often assumed that elements can be sampled from some distribution $P$, and that when an element $x$ is sampled, the probability $P$ of sampling $x$ is also known. Recent work in…

数据结构与算法 · 计算机科学 2022-08-03 Talya Eden , Jakob Bæk Tejs Houen , Shyam Narayanan , Will Rosenbaum , Jakub Tětek

Random-effects models are frequently used to synthesise information from different studies in meta-analysis. While likelihood-based inference is attractive both in terms of limiting properties and of implementation, its application in…

统计方法学 · 统计学 2018-02-16 Ioannis Kosmidis , Annamaria Guolo , Cristiano Varin

We derive convenient uniform concentration bounds and finite sample multivariate normal approximation results for quadratic forms, then describe some applications involving variance components estimation in linear random-effects models.…

统计理论 · 数学 2015-09-16 Lee H. Dicker , Murat A. Erdogdu

Standard random-effects meta-analysis relies heavily on the assumption that the underlying true effects are normally distributed. In the social sciences, where evidence synthesis increasingly involves large, highly heterogeneous datasets,…

统计方法学 · 统计学 2026-05-01 Daihe Sui , Elizabeth Tipton

Meta-analysis combines pertinent information from existing studies to provide an overall estimate of population parameters/effect sizes, as well as to quantify and explain the differences between studies. However, testing the between-study…

统计方法学 · 统计学 2020-11-13 Han Du , Ge Jiang , Zijun Ke

Random-effects models are frequently used to synthesise information from different studies in meta-analysis. While likelihood-based inference is attractive both in terms of limiting properties and of implementation, its application in…

应用统计 · 统计学 2018-05-25 Sophia Kyriakou , Ioannis Kosmidis , Nicola Sartori

When random effects are correlated with sample design variables, the usual approach of employing individual survey weights (constructed to be inversely proportional to the unit survey inclusion probabilities) to form a pseudo-likelihood no…

统计方法学 · 统计学 2021-08-26 Terrance D. Savitsky , Matthew R. Williams
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