相关论文: Dynamics of the Tyson-Hong-Thron-Novak circadian o…

We investigate the dynamics of a three-dimensional system modeling a molecular mechanism for the circadian rhythm in Drosophila. We first prove the existence of a compact attractor in the region with biological meaning. Under the assumption…

The circadian clock can adapt itself to external cues, but the molecular mechanisms and regulatory networks governing circadian oscillations' transient adjustments are still largely unknown. Here we consider the specific case of circadian…

This work is motivated by a desire to understand transitions between stable equilibria observed in Stommel's 1961 thermohaline circulation model. We adapt the model, including a forcing parameter as a dynamic slow variable. The resulting…

Ring oscillators are biochemical circuits consisting of a ring of interactions capable of sustained oscillations. The non-linear interactions between genes hinder the analytical insight into their function, usually requiring computational…

A wide range of organisms use circadian clocks to keep internal sense of daily time and regulate their behavior accordingly. Most of these clocks use intracellular genetic networks based on positive and negative regulatory elements. The…

Long and stable timescales are often observed in complex biochemical networks, such as in emergent oscillations. How these robust dynamics persist remains unclear, given the many stochastic reactions and shorter time scales demonstrated by…

Periodic forcing of nonlinear oscillators leads to a large number of dynamic behaviors. The coupling of the cell-cycle to the circadian clock provides a biological realization of such forcing. Using high throughput single-cell microscopy,…

We consider the (noisy) Kuramoto model, that is a population of N oscillators, or rotators, with mean-field interaction. Each oscillator has its own randomly chosen natural frequency (quenched disorder) and it is stirred by Brownian motion.…

The cyanobacterium Synechococcus elongatus uses both a protein phosphorylation cycle and a transcription-translation cycle to generate circadian rhythms that are highly robust against biochemical noise. We use stochastic simulations to…

We use perturbation theory and bifurcation theory to analyze the dynamical behavior of resonances, associated to a model describing a particle moving within a ring around a celestial object. The central body is modeled as a homogeneous…

Molecular circadian clocks, that are found in all nucleated cells of mammals, are known to dictate rhythms of approximately 24 hours (circa diem) to many physiological processes. This includes metabolism (e.g., temperature, hormonal blood…

Circadian rhythms are archetypical examples of nonlinear oscillations. While these oscillations are usually attributed to circuits of biochemical interactions among clock genes and proteins, recent experimental studies reveal that they are…

We study the non-equilibrium dynamics of the quantum sine-Gordon model describing a pair of Josephson-coupled one-dimensional bosonic quasi-condensates. Motivated by experimentally accessible quench procedures where the zero mode of the…

We examine the stability of hierarchical triple systems using direct $N$-body simulations without adopting a secular perturbation approximation. We estimate their disruption timescales in addition to the mere stable/unstable criterion, with…

Triple systems with low hierarchical structure are common throughout the Universe, including examples such as high-altitude lunar satellites influenced by the Earth, planetary satellites perturbed by the Sun, and stellar binaries affected…

Circadian (~24hr) clocks are self-sustained endogenous oscillators with which organisms keep track of daily and seasonal time. Circadian clocks frequently rely on interlocked transcriptional- translational feedback loops to generate rhythms…

We consider torsional oscillations of magnetars. This problem features rich dynamics due to the strong interaction between the normal modes of a magnetar's crust and a continuum of Magneto-Hydro-Dynamic (MHD) modes in its fluid core. We…

Model order reduction in high-dimensional, nonlinear dynamical systems if often enabled through fast-slow timescale separation. One such approach involves identifying a low-dimensional slow manifold to which the state rapidly converges and…

In this work, a mathematical model of self-oscillatory dynamics of the metabolism in a cell is studied. The full phase-parametric characteristics of variations of the form of attractors depending on the dissipation of a kinetic membrane…

For the relativistic string with massive ends (the meson model) and four various string baryon models (q-qq, q-q-q, Y and $\Delta$) we consider the classical quasirotational motions, which are small disturbances of the planar uniform…