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A minimal model for mechanical motion of the left ventricle is proposed. The model assumes the left ventricle to be a harmonic oscillator with two distinct phases, simulating the systolic and diastolic phases, at which both the amplitude…

医学物理 · 物理学 2007-05-23 S. Dubi , C. Dubi , Y. Dubi

A stochastic model, the product of a circulant matrix and a random normal vector, is shown to produce an evolutive long memory time series with a power law spectral density. The distribution of the time series, a beta location scale family…

综合数学 · 数学 2026-02-26 Robert Kimberk

Stochastic models of diffusion with excluded-volume effects are used to model many biological and physical systems at a discrete level. The average properties of the population may be described by a continuum model based on partial…

化学物理 · 物理学 2012-12-20 Maria Bruna , S. Jonathan Chapman

We study the effects of a probabilistic refractory period in the collective behavior of coupled discrete-time excitable cells (SIRS-like cellular automata). Using mean-field analysis and simulations, we show that a synchronized phase with…

神经元与认知 · 定量生物学 2015-03-18 Fernando Rozenblit , Mauro Copelli

To forecast the time dynamics of an epidemic, we propose a discrete stochastic model that unifies and generalizes previous approaches to the subject. Viewing a given population of individuals or groups of individuals with given health state…

Objective: to develop quantitative methods for the clinical interpretation of the ballistocardiogram (BCG). Methods: a closed-loop mathematical model of the cardiovascular system is proposed to theoretically simulate the mechanisms…

Inference for the stochastic blockmodel is currently of burgeoning interest in the statistical community, as well as in various application domains as diverse as social networks, citation networks, brain connectivity networks…

统计方法学 · 统计学 2016-02-10 Shakira Suwan , Dominic S. Lee , Runze Tang , Daniel L. Sussman , Minh Tang , Carey E. Priebe

Cardio/cerebrovascular diseases (CVD) have become one of the major health issue in our societies. But recent studies show that the present pathology tests to detect CVD are ineffectual as they do not consider different stages of platelet…

The steady state properties of the mean density population of infected cells in a viral spread is simulated by a general forest fire like cellular automaton model with two distinct populations of cells ( permissive and resistant ones) and…

adap-org · 物理学 2008-02-03 G. Camelo-Neto , S. Coutinho

We develop a theory to calculate the effective phase diffusion coefficient and the mean phase velocity in periodically driven stochastic models with two discrete states. This theory is applied to a dichotomically driven Markovian two state…

统计力学 · 物理学 2009-11-11 T. Prager , L. Schimansky-Geier

Cell motility is one of the most fundamental phenomena underlying biological processes that maintain living organisms alive. Here we introduce a simple model to describe the motility of cells which include not only time-correlated internal…

生物物理 · 物理学 2022-07-13 T. N. Azevedo , L. G. Rizzi

This paper introduces a class of stochastic models of interacting neurons with emergent dynamics similar to those seen in local cortical populations, and compares them to very simple reduced models driven by the same mean excitatory and…

神经元与认知 · 定量生物学 2017-11-07 Yao Li , Logan Chariker , Lai-Sang Young

We revisit the modeling framework introduced in [N. Loy and L. Preziosi: Bull. Math. Bio., 85, 2023] to describe the dynamics of cell orientation under cyclic stretch. We propose a reformulation based on the principles of Stochastic…

统计力学 · 物理学 2025-07-22 Rohan Abeyaratne , Sanjay Dharmaravan , Giuseppe Saccomandi , Giuseppe Tomassetti

We deal with a small enough tumor section to consider it homogeneous, such that populations of lymphocytes and cancer cells are independent of spatial coordinates. A stochastic model based in one step processes is developed to take into…

A model of the heart tissue as a conductive system with two interacting pacemakers and a refractory time, is proposed. In the parametric space of the model the phase locking areas are investigated in detail. Obtained results allow us to…

混沌动力学 · 物理学 2007-05-23 Alexander Loskutov , Sergei Rybalko , Ekaterina Zhuchkova

In this paper, we show that the recent integration of statistical models with deep recurrent neural networks provides a new way of formulating volatility (the degree of variation of time series) models that have been widely used in time…

机器学习 · 计算机科学 2018-12-06 Rui Luo , Weinan Zhang , Xiaojun Xu , Jun Wang

In this study, a new and natural way of constructing a stochastic Susceptible-Infected-Susceptible (SIS) model is proposed. This approach is natural in the sense that the disease transmission rate, $\beta$, is substituted with a generic,…

概率论 · 数学 2025-11-07 Berk Tan Perçin

Normal human heart rate shows complex fluctuations in time, which is natural, since heart rate is controlled by a large number of different feedback control loops. These unpredictable fluctuations have been shown to display fractal…

医学物理 · 物理学 2009-11-07 Tom A. Kuusela , Tony Shepherd , Jarmo Hietarinta

Two powerful and complementary experimental approaches are commonly used to study the cell cycle and cell biology: One class of experiments characterizes the statistics (or demographics) of an unsynchronized exponentially-growing…

生物物理 · 物理学 2022-02-02 Dean Huang , Teresa Lo , Houra Merrikh , Paul A. Wiggins

We present a Bayesian approach to estimate the parameters of mathematical models of cardiac electrophysiology with quantified uncertainty. Such models capture the dynamics of the electrical signal that coordinates the muscle cell…

数值分析 · 数学 2026-04-02 Maarten Volkaerts , Marie Cloet , Hans Dierckx , Piet Claus , Giovanni Samaey