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Cancer immunotherapy provides durable clinical benefit in only a small fraction of patients, particularly due to a lack of reliable biomarkers for accurate prediction of treatment outcomes and evaluation of response. Here, we demonstrate…

Microscopic pyramidal pits in a reflective surface, a geometry similar to a retroreflector, are frequently used to enhance signal strength. The enhancement effect is generally attributed to surface plasmons, however, the sub-wavelength to…

光学 · 物理学 2009-12-18 M. Mechler , S. V. Kukhlevsky , A. Mechler , D. McNaughton

In 2006 Mom\v{c}ilovi\'c et al. measured radioactvity levels of 210Po and 210Bi by alpha- and beta-measurements resp. to determine the natural distribuion of environmental radon daughters in the different brain areas of an Alzheimer Disease…

医学物理 · 物理学 2018-06-26 Michael S. Pravikoff , Christine Marquet , Philippe Hubert

We calculate the eigenstates of a diatomic molecule in a range of model mean-field potentials, and evaluate the evolution of their associated Raman spectra with field strength. We demonstrate that dramatic changes in the appearance of the…

材料科学 · 物理学 2022-02-22 Peter I. C. Cooke , Ioan B. Magdău , Graeme J. Ackland

We demonstrate stimulated Raman gain using a broadband LED Stokes source to measure vibrational spectra of aqueous glucose solutions. This versatile and cost-effective method increases Raman signal for a variety of applications. We measured…

应用物理 · 物理学 2018-09-14 Peter Bullen , Ioannis Kymissis , Adler Perotte

With the heterogeneous nature of tissue texture, using a single resolution approach for optimum classification might not suffice. In contrast, a multiresolution wavelet packet analysis can decompose the input signal into a set of frequency…

计算机视觉与模式识别 · 计算机科学 2016-01-05 Omar S. Al-Kadi

Grating spectra exhibit sharp variations of the scattered light, known as grating anomalies. The latter are due to resonances that have fascinated specialists of optics and physics for decades and are nowadays used in many applications. We…

光学 · 物理学 2019-09-10 Alexandre Gras , Wei Yan , Philippe Lalanne

Raman optical activity spectra of $\Lambda$-tris-(ethylenediamine)-rhodium(III) ([Rh(en)$_3$]$^{3+}$) have been calculated at 16 on-, near-, and off-resonant wavelengths between 290 nm and 800 nm. The resulting spectra are analyzed in…

化学物理 · 物理学 2020-07-01 Thomas Weymuth

Tumour heterogeneity is increasingly recognized as a major obstacle to therapeutic success across neuro-oncology. Gliomas are characterised by distinct combinations of genetic and epigenetic alterations, resulting in complex interactions…

Diffuse gliomas are malignant brain tumors that grow widespread through the brain. The complex interactions between neoplastic cells and normal tissue, as well as the treatment-induced changes often encountered, make glioma tumor growth…

We advance theoretical methods for studying propagation effects in the Fast Radio Burst (FRB) spectra. We derive their autocorrelation function in the model with diffractive lensing and strong Kolmogorov-type scintillations and analytically…

高能天体物理现象 · 物理学 2022-02-01 D. G. Levkov , A. G. Panin , I. I. Tkachev

A mechanism is explored whereby intense laser radiation induces an optical force between the constituent atoms of a molecule. In the case of a diatomic molecule the effect results in a modification of the vibrational potential, and using…

光学 · 物理学 2007-05-23 D. L. Andrews R. G. Crisp

The bosonisation technique is used to calculate the resonant Raman spectrum of a quantum wire with two electronic sub-bands occupied. Close to resonance, the cross section at frequencies in the region of the inter sub-band transitions shows…

强关联电子 · 物理学 2009-11-07 E. Mariani , M. Sassetti , B. Kramer

Glioblastoma is one of the most aggressive and deadliest types of brain cancer, with low survival rates compared to other types of cancer. Analysis of Magnetic Resonance Imaging (MRI) scans is one of the most effective methods for the…

图像与视频处理 · 电气工程与系统科学 2023-12-20 Huafeng Liu , Benjamin Dowdell , Todd Engelder , Zarah Pulmano , Nicolas Osa , Arko Barman

Diffuse gliomas are highly infiltrative tumors whose early diagnosis and follow-up usually rely on magnetic resonance imaging (MRI). However, the limited sensitivity of this technique makes it impossible to directly assess the extent of the…

Accurate detection of brain tumors could save lots of lives and increasing the accuracy of this binary classification even as much as a few percent has high importance. Neural Gas Networks (NGN) is a fast, unsupervised algorithm that could…

图像与视频处理 · 电气工程与系统科学 2023-01-31 S. Muhammad Hossein Mousavi

Light scattering limits the penetration depth of non-invasive Raman spectroscopy in biological media. While safe levels of irradiation may be adequate to analyze superficial tissue, scattering of the pump beam reduces the Raman signal to…

Raman Spectroscopy is able to probe disorder in graphene through defect-activated peaks. It is of great interest to link these features to the nature of disorder. Here we present a detailed analysis of the Raman spectra of graphene…

介观与纳米尺度物理 · 物理学 2012-07-10 Axel Eckmann , Alexandre Felten , Artem Mishchenko , Liam Britnell , Ralph Krupke , Kostya S. Novoselov , Cinzia Casiraghi

Complex gene interactions play a significant role in cancer progression, driving cellular behaviors that contribute to tumor growth, invasion, and metastasis. Gene co-expression networks model the functional connectivity between genes under…

分子网络 · 定量生物学 2024-11-27 Radwa Adel , Ercan Engin Kuruoglu

Few-layer graphene possesses low-energy carriers which behave as massive fermions, exhibiting intriguing properties in both transport and light scattering experiments. Lowering the excitation energy of resonance Raman spectroscopy down to…