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Parkinson's disease (PD) is a chronic neurodegenerative disease. Early diagnosis is essential to mitigate the progressive deterioration of patients' quality of life. The most characteristic motor symptoms are very mild in the early stages,…

机器学习 · 计算机科学 2026-01-27 Beatriz Pérez-Sánchez , Noelia Sánchez-Maroño , Miguel A. Díaz-Freire

Parkinson's disease (PD), a severe and progressive neurological illness, affects millions of individuals worldwide. For effective treatment and management of PD, an accurate and early diagnosis is crucial. This study presents a deep…

信号处理 · 电气工程与系统科学 2023-08-16 Niloufar Delfan , Mohammadreza Shahsavari , Sadiq Hussain , Robertas Damaševičius , U. Rajendra Acharya

The assessment of Parkinson's disease (PD) poses a significant challenge as it is influenced by various factors which lead to a complex and fluctuating symptom manifestation. Thus, a frequent and objective PD assessment is highly valuable…

Early detection of Parkinson's disease (PD) is important which can enable early initiation of therapeutic interventions and management strategies. However, methods for early detection still remain an unmet clinical need in PD. In this…

应用统计 · 统计学 2018-10-04 R Prashanth , Sumantra Dutta Roy

Fundamental knowledge in activity recognition of individuals with motor disorders such as Parkinson's disease (PD) has been primarily limited to detection of steady-state/static tasks (sitting, standing, walking). To date, identification of…

信号处理 · 电气工程与系统科学 2021-10-13 Mahdieh Kazemimoghadam , Nicholas P. Fey

The paper presents a novel approach, based on deep learning, for diagnosis of Parkinson's disease through medical imaging. The approach includes analysis and use of the knowledge extracted by Deep Convolutional and Recurrent Neural Networks…

机器学习 · 计算机科学 2019-11-26 James Wingate , Ilianna Kollia , Luc Bidaut , Stefanos Kollias

Parkinson's disease (PD) is a degenerative and progressive neurological condition. Early diagnosis can improve treatment for patients and is performed through dopaminergic imaging techniques like the SPECT DaTscan. In this study, we propose…

计算机视觉与模式识别 · 计算机科学 2020-08-04 Pavan Rajkumar Magesh , Richard Delwin Myloth , Rijo Jackson Tom

Evaluating neurological disorders such as Parkinson's disease (PD) is a challenging task that requires the assessment of several motor and non-motor functions. In this paper, we present an end-to-end deep learning framework to measure PD…

计算机视觉与模式识别 · 计算机科学 2020-12-25 Amirhossein Dadashzadeh , Alan Whone , Michal Rolinski , Majid Mirmehdi

Parkinson's disease (PD) is a progressive neurological disorder primarily affecting motor function resulting in tremor at rest, rigidity, bradykinesia, and postural instability. The physical severity of PD impairments can be quantified…

计算机视觉与模式识别 · 计算机科学 2020-07-20 Mandy Lu , Kathleen Poston , Adolf Pfefferbaum , Edith V. Sullivan , Li Fei-Fei , Kilian M. Pohl , Juan Carlos Niebles , Ehsan Adeli

Interacting, self-propelled particles such as epithelial cells can dynamically self-organize into complex multicellular patterns, which are challenging to classify without a priori information. Classically, different phases and phase…

定量方法 · 定量生物学 2021-01-19 Dhananjay Bhaskar , William Y. Zhang , Ian Y. Wong

Parkinson's Disease (PD) is the second most common neurodegenerative disorder. The existing assessment method for PD is usually the Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) to assess the severity of…

计算机视觉与模式识别 · 计算机科学 2024-04-03 Xiang Xiang , Zihan Zhang , Jing Ma , Yao Deng

Parkinson's disease (PD) is a highly heterogeneous disease, including which motor symptoms are dominating. Imaging biomarkers that support subtype stratification could also improve biological understanding and study design, and enable…

Parkinson's Disease (PD) is a progressive nervous system disorder that has affected more than 5.8 million people, especially the elderly. Due to the complexity of its symptoms and its similarity to other neurological disorders, early…

人工智能 · 计算机科学 2022-11-29 Jingwei Li , Ruitian Wu , Tzu-liang Huang , Zian Pan , Ming-chun Huang

Parkinson's disease (PD) is a neurodegenerative disease affecting about 1% of people over the age of 60, causing motor impairments that impede hand coordination activities such as writing and drawing. Many approaches have tried to support…

计算机视觉与模式识别 · 计算机科学 2025-12-30 Mhd Adnan Albani , Riad Sonbol

Topological Data Analysis (TDA) is the collection of mathematical tools that capture the structure of shapes in data. Despite computational topology and computational geometry, the utilization of TDA in time series and signal processing is…

信息检索 · 计算机科学 2018-10-23 Shafie Gholizadeh , Wlodek Zadrozny

Topological methods can provide a way of proposing new metrics and methods of scrutinising data, that otherwise may be overlooked. In this work, a method of quantifying the shape of data, via a topic called topological data analysis will be…

机器学习 · 统计学 2022-09-25 Tristan Gowdridge , Nikolaos Dervilis , Keith Worden

Parkinson's disease is the world's fastest-growing neurological disorder. Research to elucidate the mechanisms of Parkinson's disease and automate diagnostics would greatly improve the treatment of patients with Parkinson's disease. Current…

机器学习 · 计算机科学 2024-02-20 Charlie Tran , Kai Shen , Kang Liu , Akshay Ashok , Adolfo Ramirez-Zamora , Jinghua Chen , Yulin Li , Ruogu Fang

Clinical methods that assess gait in Parkinson's Disease (PD) are mostly qualitative. Quantitative methods necessitate costly instrumentation or cumbersome wearable devices, which limits their usability. Only few of these methods can…

机器学习 · 计算机科学 2020-06-23 Nabeel Seedat , Vered Aharonson

Accurate assessment of Parkinsonian tremor is vital for monitoring disease progression and evaluating treatment efficacy. We introduce a pixel-based deep learning model designed to analyse postural tremor in Parkinson's disease (PD) from…

计算机视觉与模式识别 · 计算机科学 2024-09-04 Felipe Duque-Quiceno , Grzegorz Sarapata , Yuriy Dushin , Miles Allen , Jonathan O'Keeffe

Parkinson's disease is a progressive and slowly developing neurodegenerative disease, characterized by dopaminergic neuron loss in the substantia nigra region of the brain. Despite extensive research by scientists, there is not yet a cure…

定量方法 · 定量生物学 2024-08-31 Pratham Kankariya , Rachita Rode , Kevin Mudaliar , Pranali Hatode