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相关论文: Topological Descriptors for Parkinson's Disease Cl…

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Parkinson's disease (PD) is a common neurological disorder characterized by gait impairment. PD has no cure, and an impediment to developing a treatment is the lack of any accepted method to predict disease progression rate. The primary aim…

信号处理 · 电气工程与系统科学 2019-11-26 Vyom Raval , Kevin P. Nguyen , Ashley Gerald , Richard B. Dewey , Albert Montillo

Over the last two decades, topological data analysis (TDA) has emerged as a very powerful data analytic approach which can deal with various data modalities of varying complexities. One of the most commonly used tools in TDA is persistent…

统计方法学 · 统计学 2025-12-08 Anass El Yaagoubi Bourakna , Moo K. Chung , Hernando Ombao

Speech-based Parkinson's disease (PD) detection has gained attention for its automated, cost-effective, and non-intrusive nature. As research studies usually rely on data from diagnostic-oriented speech tasks, this work explores the…

音频与语音处理 · 电气工程与系统科学 2025-08-29 Terry Yi Zhong , Esther Janse , Cristian Tejedor-Garcia , Louis ten Bosch , Martha Larson

Parkinson's disease (PD) is a progressive disorder in which symptom burden and functional impairment evolve over time, making severity staging essential for clinical monitoring and treatment planning. However, many computational studies…

机器学习 · 计算机科学 2026-04-21 Md Mezbahul Islam , John Michael Templeton , Christian Poellabauer , Ananda Mohan Mondal

Parkinson's disease (PD) presents a growing global challenge, affecting over 10 million individuals, with prevalence expected to double by 2040. Early diagnosis remains difficult due to the late emergence of motor symptoms and limitations…

机器学习 · 计算机科学 2025-10-21 Arianna Francesconi , Donato Cappetta , Fabio Rebecchi , Paolo Soda , Valerio Guarrasi , Rosa Sicilia

Deep learning holds tremendous potential in healthcare for uncovering hidden patterns within extensive clinical datasets, aiding in the diagnosis of various diseases. Parkinson's disease (PD) is a neurodegenerative condition characterized…

计算机视觉与模式识别 · 计算机科学 2024-12-10 Aqib Nazir Mir , Iqra Nissar , Mumtaz Ahmed , Sarfaraz Masood , Danish Raza Rizvi

Parkinsons Disease (PD) is a neurodegenerative disorder resulting in motor deficits due to advancing degeneration of dopaminergic neurons. PD patients report experiencing tremor, rigidity, visual impairment, bradykinesia, and several…

计算机视觉与模式识别 · 计算机科学 2023-04-05 Krish Desai

The rapid advancement of medical technology has led to an exponential increase in multi-modal medical data, including imaging, genomics, and electronic health records (EHRs). Graph neural networks (GNNs) have been widely used to represent…

定量方法 · 定量生物学 2024-10-03 Favour Nerrise , Alice Louise Heiman , Ehsan Adeli

Parkinsons Disease is a neurological disorder and prevalent in elderly people. Traditional ways to diagnose the disease rely on in-person subjective clinical evaluations on the quality of a set of activity tests. The high-resolution…

机器学习 · 计算机科学 2020-10-16 Weijian Li , Wei Zhu , E. Ray Dorsey , Jiebo Luo

The stage and severity of Parkinson's disease (PD) is an important factor to consider for taking effective therapeutic decisions. Although the Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) provides an…

应用统计 · 统计学 2018-05-30 R. Prashanth , Sumantra Dutta Roy

This paper presents a novel deep learning enabled, video based analysis framework for assessing the Unified Parkinsons Disease Rating Scale (UPDRS) that can be used in the clinic or at home. We report results from comparing the performance…

计算机视觉与模式识别 · 计算机科学 2021-04-13 Deval Mehta , Umar Asif , Tian Hao , Erhan Bilal , Stefan Von Cavallar , Stefan Harrer , Jeffrey Rogers

Parkinson's Disease (PD) affects millions globally, impacting movement. Prior research utilized deep learning for PD prediction, primarily focusing on medical images, neglecting the data's underlying manifold structure. This work proposes a…

计算机视觉与模式识别 · 计算机科学 2024-08-27 Jun-En Ding , Chien-Chin Hsu , Feng Liu

In this work, the issue of Parkinson's disease (PD) diagnostics using non-invasive antemortem techniques was tackled. A deep learning approach for classification of raw speech recordings in patients with diagnosed PD was proposed. The core…

计算与语言 · 计算机科学 2022-04-28 Maurycy Chronowski , Maciej Klaczynski , Malgorzata Dec-Cwiek , Karolina Porebska

Topological data analysis (TDA) is a versatile tool that can be used to extract scientific knowledge from complex pattern formation processes. However, the physics correspondence between the features obtained from TDA and pattern dynamics…

斑图形成与孤子 · 物理学 2024-07-09 Yoh-ichi Mototake , Masaichiro Mizumaki , Kazue Kudo , Kenji Fukumizu

Discriminating patients with Alzheimer's disease (AD) from healthy subjects is a crucial task in the research of Alzheimer's disease. The task can be potentially achieved by linear discriminant analysis (LDA), which is one of the most…

统计方法学 · 统计学 2020-05-05 Yingjie Li , Liangliang Zhang , Tapabrata Maiti

Electroencephalography has been established as an effective method for detecting Parkinson's disease, typically diagnosed early.Current Parkinson's disease detection methods have shown significant success within individual datasets,…

机器学习 · 计算机科学 2025-08-21 Qian Zhang , Ruilin Zhang , Biaokai Zhu , Xun Han , Jun Xiao , Yifan Liu , Zhe Wang

In heterogeneous disorders like Parkinson's disease (PD), differentiating the affected population into subgroups plays a key role in future research. Discovering subgroups can lead to improved treatments through more powerful enrichment of…

统计方法学 · 统计学 2023-08-08 Elliot Burghardt , Daniel Sewell , Joseph Cavanaugh

Despite the remarkable accuracies attained by machine learning classifiers to separate complex datasets in a supervised fashion, most of their operation falls short to provide an informed intuition about the structure of data, and, what is…

机器学习 · 计算机科学 2023-03-09 Aina Ferrà , Gloria Cecchini , Fritz-Pere Nobbe Fisas , Carles Casacuberta , Ignasi Cos

Parkinson's disease (PD) is a chronic neurodegenerative disease. It shows multiple motor symptoms such as tremor, bradykinesia, postural instability, freezing of gait (FoG). PD is currently diagnosed clinically through physical exam by…

机器学习 · 计算机科学 2026-04-21 Meheru Zannat

Parkinson's disease (PD) is debilitating, progressive, and clinically marked by motor symptoms. As the second most common neurodegenerative disease in the world, it affects over 10 million lives globally. Existing diagnoses methods have…

机器学习 · 计算机科学 2021-11-30 Riya Tyagi , Tanish Tyagi , Ming Wang , Lujin Zhang