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Causality lays the foundation for the trajectory of our world. Causal inference (CI), which aims to infer intrinsic causal relations among variables of interest, has emerged as a crucial research topic. Nevertheless, the lack of observation…

机器学习 · 计算机科学 2024-06-21 Yaochen Zhu , Yinhan He , Jing Ma , Mengxuan Hu , Sheng Li , Jundong Li

In causal mediation analysis, nonparametric identification of the pure (natural) direct effect typically relies on, in addition to no unobserved pre-exposure confounding, fundamental assumptions of (i) so-called…

统计方法学 · 统计学 2015-09-08 Caleb H. Miles , Phyllis Kanki , Seema Meloni , Eric J. Tchetgen Tchetgen

Causal mediation analysis can improve understanding of the mechanisms underlying epidemiologic associations. However, the utility of natural direct and indirect effect estimation has been limited by the assumption of no confounder of the…

应用统计 · 统计学 2020-06-16 Kara E. Rudolph , Oleg Sofrygin , Wenjing Zheng , Mark J. van der Laan

In causal analysis, understanding the causal mechanisms through which an intervention or treatment affects an outcome is often of central interest. We propose a test to evaluate (i) whether the causal effect of a treatment that is randomly…

计量经济学 · 经济学 2026-03-05 Martin Huber , Kevin Kloiber , Lukáš Lafférs

Recent critiques of Physics Education Research (PER) studies have revoiced the critical issues when drawing causal inferences from observational data where no intervention is present. In response to a call for a "causal reasoning primer",…

统计方法学 · 统计学 2023-05-25 Vidushi Adlakha , Eric Kuo

Studying causal effects of continuous treatments is important for gaining a deeper understanding of many interventions, policies, or medications, yet researchers are often left with observational studies for doing so. In the observational…

统计方法学 · 统计学 2023-06-16 Jared D. Huling , Noah Greifer , Guanhua Chen

Estimating causal effects among different events is of great importance to critical fields such as drug development. Nevertheless, the data features associated with events may be distributed across various silos and remain private within…

机器学习 · 计算机科学 2024-01-05 Yuxuan Liu , Haozhao Wang , Shuang Wang , Zhiming He , Wenchao Xu , Jialiang Zhu , Fan Yang

We report assumption-free bounds for any contrast between the probabilities of the potential outcome under exposure and non-exposure when the confounders are missing not at random. We assume that the missingness mechanism is…

统计方法学 · 统计学 2024-11-04 Jose M. Peña

Estimating causal effects from observational data requires identifying valid adjustment sets. This task is especially challenging in realistic settings where latent confounding and feedback loops are present. Existing approaches typically…

机器学习 · 计算机科学 2026-05-08 Ana Leticia Garcez Vicente , Gijs van Seeventer , Saber Salehkaleybar

Mediation analysis serves as a crucial tool to obtain causal inference based on directed acyclic graphs, which has been widely employed in the areas of biomedical science, social science, epidemiology and psychology. Decomposition of total…

统计方法学 · 统计学 2020-04-14 Xin Gao , Li Li , Li Luo

Causal discovery is to learn cause-effect relationships among variables given observational data and is important for many applications. Existing causal discovery methods assume data sufficiency, which may not be the case in many real world…

机器学习 · 计算机科学 2022-06-20 Zijun Cui , Naiyu Yin , Yuru Wang , Qiang Ji

Mediation analysis is widely used for investigating direct and indirect causal pathways through which an effect arises. However, many mediation analysis studies are challenged by missingness in the mediator and outcome. In general, when the…

统计方法学 · 统计学 2023-09-25 Shuozhi Zuo , Debashis Ghosh , Peng Ding , Fan Yang

Interference bias is a major impediment to identifying causal effects in real-world settings. For example, vaccination reduces the transmission of a virus in a population such that everyone benefits -- even those who are not treated. This…

统计方法学 · 统计学 2025-03-25 Michael O'Riordan , Ciarán M. Gilligan-Lee

Causal inference analysis is the estimation of the effects of actions on outcomes. In the context of healthcare data this means estimating the outcome of counter-factual treatments (i.e. including treatments that were not observed) on a…

统计方法学 · 统计学 2018-03-21 Yishai Shimoni , Chen Yanover , Ehud Karavani , Yaara Goldschmnidt

Causal mediation analysis seeks to investigate how the treatment effect of an exposure on outcomes is mediated through intermediate variables. Although many applications involve longitudinal data, the existing methods are not directly…

应用统计 · 统计学 2021-02-24 Shuxi Zeng , Stacy Rosenbaum , Elizabeth Archie , Susan Alberts , Fan Li

Natural experiments are a cornerstone of applied economics, providing settings for estimating causal effects with a compelling argument for treatment randomisation, but give little indication of the mechanisms behind causal effects. Causal…

计量经济学 · 经济学 2025-10-07 Senan Hogan-Hennessy

Causal inference is a science with multi-disciplinary evolution and applications. On the one hand, it measures effects of treatments in observational data based on experimental designs and rigorous statistical inference to draw causal…

统计方法学 · 统计学 2022-09-05 Jingying Zeng , Run Wang

This paper is concerned with test of the conditional independence. We first establish an equivalence between the conditional independence and the mutual independence. Based on the equivalence, we propose an index to measure the conditional…

统计方法学 · 统计学 2021-05-18 Zhanrui Cai , Runze Li , Yaowu Zhang

Causal mediation analysis is an important statistical method in social and medical studies, as it can provide insights about why an intervention works and inform the development of future interventions. Currently, most causal mediation…

统计方法学 · 统计学 2016-01-26 Cheng Zheng , David C. Atkins , Melissa A. Lewis , Xiao-Hua Zhou

In cluster-randomized trials (CRTs), there is emerging interest in exploring the causal mechanism in which a cluster-level treatment affects the outcome through an intermediate outcome. The majority of existing causal mediation methods are…

统计方法学 · 统计学 2026-01-12 Chao Cheng , Fan Li