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The fixed-X knockoff filter is a flexible framework for variable selection with false discovery rate (FDR) control in linear models with arbitrary design matrices (of full column rank) and it allows for finite-sample selective inference via…

统计理论 · 数学 2023-11-28 Mehrdad Pournaderi , Yu Xiang

This paper develops a method based on model-X knockoffs to find conditional associations that are consistent across diverse environments, controlling the false discovery rate. The motivation for this problem is that large data sets may…

统计方法学 · 统计学 2021-06-09 Shuangning Li , Matteo Sesia , Yaniv Romano , Emmanuel Candès , Chiara Sabatti

Recent discoveries suggest that our gut microbiome plays an important role in our health and wellbeing. However, the gut microbiome data are intricate; for example, the microbial diversity in the gut makes the data high-dimensional. While…

统计方法学 · 统计学 2021-03-02 Fang Xie , Johannes Lederer

Many contemporary large-scale applications involve building interpretable models linking a large set of potential covariates to a response in a nonlinear fashion, such as when the response is binary. Although this modeling problem has been…

统计方法学 · 统计学 2017-12-13 Emmanuel Candes , Yingying Fan , Lucas Janson , Jinchi Lv

The recently proposed fixed-X knockoff is a powerful variable selection procedure that controls the false discovery rate (FDR) in any finite-sample setting, yet its theoretical insights are difficult to show beyond Gaussian linear models.…

统计方法学 · 统计学 2023-11-28 Han Su , Panxu Yuan , Qingyang Sun , Mengxi Yi , Gaorong Li

Knockoffs is a new framework for controlling the false discovery rate (FDR) in multiple hypothesis testing problems involving complex statistical models. While there has been great emphasis on Type-I error control, Type-II errors have been…

统计方法学 · 统计学 2017-12-19 Asaf Weinstein , Rina Barber , Emmanuel Candes

Controlling the False Discovery Rate (FDR) is critical for reproducible variable selection, especially given the prevalence of complex predictive modeling. The recent Split Knockoff method, an extension of the canonical Knockoffs framework,…

统计方法学 · 统计学 2025-09-05 Yang Cao , Hangyu Lin , Xinwei Sun , Yuan Yao

Continuous improvement in medical imaging techniques allows the acquisition of higher-resolution images. When these are used in a predictive setting, a greater number of explanatory variables are potentially related to the dependent…

统计理论 · 数学 2019-03-13 Tuan-Binh Nguyen , Jérôme-Alexis Chevalier , Bertrand Thirion

Consider a case-control study in which we have a random sample, constructed in such a way that the proportion of cases in our sample is different from that in the general population---for instance, the sample is constructed to achieve a…

统计方法学 · 统计学 2019-01-01 Rina Foygel Barber , Emmanuel Candes

We present a novel method for controlling the $k$-familywise error rate ($k$-FWER) in the linear regression setting using the knockoffs framework first introduced by Barber and Cand\`es. Our procedure, which we also refer to as knockoffs,…

统计方法学 · 统计学 2015-11-10 Lucas Janson , Weijie Su

Controlling the False Discovery Rate (FDR) in a variable selection procedure is critical for reproducible discoveries, and it has been extensively studied in sparse linear models. However, it remains largely open in scenarios where the…

统计方法学 · 统计学 2023-11-16 Yang Cao , Xinwei Sun , Yuan Yao

The knockoffs is a recently proposed powerful framework that effectively controls the false discovery rate (FDR) for variable selection. However, none of the existing knockoff solutions are directly suited to handle multivariate or…

统计方法学 · 统计学 2024-06-28 Xinghao Qiao , Mingya Long , Qizhai Li

We propose one-at-a-time knockoffs (OATK), a new methodology for detecting important explanatory variables in linear regression models while controlling the false discovery rate (FDR). For each explanatory variable, OATK generates a…

统计方法学 · 统计学 2025-02-27 Charlie K. Guan , Zhimei Ren , Daniel W. Apley

The knockoff filter is a powerful tool for controlled variable selection with false discovery rate (FDR) control. In this paper, we leverage e-values to allow the nominal FDR level to be switched post-hoc, after looking at the data and…

统计方法学 · 统计学 2026-02-20 Lasse Fischer , Konstantinos Sechidis

The recent paper Cand\`es et al. (2018) introduced model-X knockoffs, a method for variable selection that provably and non-asymptotically controls the false discovery rate with no restrictions or assumptions on the dimensionality of the…

统计方法学 · 统计学 2020-06-16 Dongming Huang , Lucas Janson

Model-X knockoff has garnered significant attention among various feature selection methods due to its guarantees for controlling the false discovery rate (FDR). Since its introduction in parametric design, knockoff techniques have evolved…

机器学习 · 计算机科学 2024-11-11 Hongyu Shen , Yici Yan , Zhizhen Zhao

Knockoff variable selection is a powerful framework that creates synthetic knockoff variables to mirror the correlation structure of the observed features, enabling principled control of the false discovery rate in variable selection.…

统计方法学 · 统计学 2025-08-21 Evan Mason , Zhe Fei

Model-X knockoff framework offers a model-free variable selection method that ensures finite sample false discovery rate (FDR) control. However, the complexity of generating knockoff variables, coupled with the model-free assumption,…

统计方法学 · 统计学 2025-06-12 Zhanrui Cai , Yingying Fan , Lan Gao

In many research fields, researchers aim to identify significant associations between a set of explanatory variables and a response while controlling the FDR. The Knockoff filter has been recently proposed in the frequentist paradigm to…

统计方法学 · 统计学 2026-04-22 Lorenzo Focardi-Olmi , Anna Gottard , Michele Guindani , Marina Vannucci

This paper introduces an innovative method for conducting conditional independence testing in high-dimensional data, facilitating the automated discovery of significant associations within distinct subgroups of a population, all while…

统计方法学 · 统计学 2023-09-19 Matteo Sesia , Tianshu Sun