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Arguing about the equilibrium distribution of continuous-time Markov chains can be vital for showing properties about the underlying systems. For example in biological systems, bistability of a chemical reaction network can hint at its…

概率论 · 数学 2010-07-20 Tugrul Dayar , Holger Hermanns , David Spieler , Verena Wolf

Population dynamics are often subject to random independent changes in the environment. For the two strategy stochastic replicator dynamic, we assume that stochastic changes in the environment replace the payoffs and variance. This is…

种群与进化 · 定量生物学 2014-06-11 Andrew Vlasic

Stochastic reaction networks are mathematical models frequently used in, but not limited to, biochemistry. These models are continuous-time Markov chains whose transition rates depend on certain parameters called rate constants, which…

概率论 · 数学 2025-08-14 Daniele Cappelletti , Aidan Howells , Chuang Xu

Stochastic reaction networks are mathematical models with a wide range of applications in biochemistry, ecology, and epidemiology, and are often complex to analyze. Except for some special cases, it is generally difficult to predict how the…

概率论 · 数学 2026-04-02 Daniele Cappelletti , Giulio Cuniberti , Paola Siri

It has recently been shown that structural conditions on the reaction network, rather than a 'fine-tuning' of system parameters, often suffice to impart 'absolute concentration robustness' on a wide class of biologically relevant,…

概率论 · 数学 2014-01-20 David F. Anderson , German Enciso , Matthew Johnston

Stochastic reaction networks are dynamical models of biochemical reaction systems and form a particular class of continuous-time Markov chains on $\mathbb{N}^n$. Here we provide a fundamental characterisation that connects structural…

概率论 · 数学 2018-05-22 Daniele Cappelletti , Carsten Wiuf

We analyze ecological systems that are influenced by random environmental fluctuations. We first provide general conditions which ensure that the species coexist and the system converges to a unique invariant probability measure (stationary…

种群与进化 · 定量生物学 2021-05-19 Alexandru Hening , Yao Li

We introduce a stochastic model of coupled genetic oscillators in which chains of chemical events involved in gene regulation and expression are represented as sequences of Poisson processes. We characterize steady states by their…

生物物理 · 物理学 2018-03-28 David J. Jörg , Luis G. Morelli , Frank Jülicher

We study the long-term behavior of two piecewise-deterministic Markov processes used to model stochastic gene regulatory networks with bursting dynamics. Under regularity assumptions on the jump rate, we prove the existence and uniqueness…

概率论 · 数学 2026-05-12 Mathilde Gaillard , Ulysse Herbach

A reaction network is a chemical system involving multiple reactions and chemical species. Stochastic models of such networks treat the system as a continuous time Markov chain on the number of molecules of each species with reactions as…

概率论 · 数学 2007-05-23 Karen Ball , Thomas G. Kurtz , Lea Popovic , Greg Rempala

Reaction networks are systems in which the populations of a finite number of species evolve through predefined interactions. Such networks are found as modeling tools in many biological disciplines such as biochemistry, ecology,…

分子网络 · 定量生物学 2015-06-15 Ankit Gupta , Corentin Briat , Mustafa Khammash

Focusing on stochastic systems arising in mean-field models, the systems under consideration belong to the class of switching diffusions, in which continuous dynamics and discrete events coexist and interact. The discrete events are modeled…

概率论 · 数学 2019-01-18 Son L. Nguyen , George Yin , Tuan A. Hoang

For Markov chains and Markov processes exhibiting a form of stochastic monotonicity (larger states shift up transition probabilities in terms of stochastic dominance), stability and ergodicity results can be obtained using order-theoretic…

概率论 · 数学 2024-10-01 Takashi Kamihigashi , John Stachurski

Markov branching systems form a fundamental class of stochastic models that are extensively applied in biology, physics, finance, and other domains. These systems are distinguished by their continuous-time evolution and inherent branching…

Stochastic reaction network models arise in intracellular chemical reactions, epidemiological models and other population process models, and are a class of continuous time Markov chains which have the nonnegative integer lattice as state…

数值分析 · 数学 2024-07-26 Muruhan Rathinam , Mingkai Yu

We consider stochastic reaction networks modeled by continuous-time Markov chains. Such reaction networks often contain many reactions, potentially occurring at different time scales, and have unknown parameters (kinetic rates, total…

概率论 · 数学 2023-02-20 Linard Hoessly , Carsten Wiuf

Stochastic Chemical Reaction Networks are continuous time Markov chain models that describe the time evolution of the molecular counts of species interacting stochastically via discrete reactions. Such models are ubiquitous in systems and…

定量方法 · 定量生物学 2024-02-01 Theodore W. Grunberg , Domitilla Del Vecchio

Populations interact non-linearly and are influenced by environmental fluctuations. In order to have realistic mathematical models, one needs to take into account that the environmental fluctuations are inherently stochastic. Often,…

概率论 · 数学 2025-07-29 Alexandru Hening , Siddharth Sabharwal

Based on the theory of stochastic chemical kinetics, the inherent randomness and stochasticity of biochemical reaction networks can be accurately described by discrete-state continuous-time Markov chains. The analysis of such processes is,…

数值分析 · 数学 2014-10-14 Andreychenko Alexander , Mikeev Linar , Wolf Verena

We consider long-time behavior of dynamical systems perturbed by a small noise. Under certain conditions, a slow component of such a motion, which is most important for long- time evolution, can be described as a motion on the cone of…

概率论 · 数学 2015-06-22 Mark Freidlin
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