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In this paper, we study a system of three evolutionary operator equations involving fractional powers of selfadjoint, monotone, unbounded, linear operators having compact resolvents. This system constitutes a generalization of a phase field…

偏微分方程分析 · 数学 2019-06-27 Pierluigi Colli , Gianni Gilardi , Jürgen Sprekels

In this paper, the authors study the distributed optimal control of a system of three evolutionary equations involving fractional powers of three selfadjoint, monotone, unbounded linear operators having compact resolvents. The system is a…

最优化与控制 · 数学 2019-07-25 Pierluigi Colli , Gianni Gilardi , Jürgen Sprekels

This paper is concerned with a phase field system of Cahn-Hilliard type that is related to a tumor growth model and consists of three equations in terms of the variables order parameter, chemical potential and nutrient concentration. This…

偏微分方程分析 · 数学 2015-03-04 Pierluigi Colli , Gianni Gilardi , Elisabetta Rocca , Jürgen Sprekels

This paper deals with a general system of equations and conditions arising from a mathematical model of prostate cancer growth with chemotherapy and antiangiogenic therapy that has been recently introduced and analyzed (see [P. Colli et…

偏微分方程分析 · 数学 2021-04-02 Pierluigi Colli , Gianni Gilardi , Jürgen Sprekels

We consider a particular phase field system which physical context is that of tumor growth dynamics. The model we deal with consists of a Cahn-Hilliard type equation governing the evolution of the phase variable which takes into account the…

偏微分方程分析 · 数学 2019-08-30 Andrea Signori

This paper provides a unified mathematical analysis of a family of non-local diffuse interface models for tumor growth describing evolutions driven by long-range interactions. These integro-partial differential equations model cell-to-cell…

偏微分方程分析 · 数学 2021-07-07 Luca Scarpa , Andrea Signori

We introduce a nonisothermal phase-field system of Caginalp type that describes tumor growth under hyperthermia. The model couples a possibly viscous Cahn-Hilliard equation, governing the evolution of the healthy and tumor phases, with an…

偏微分方程分析 · 数学 2025-10-13 Giulia Cavalleri , Pierluigi Colli , Elisabetta Rocca

In the recent paper `Well-posedness and regularity for a generalized fractional Cahn-Hilliard system' (Atti Accad. Naz. Lincei Rend. Lincei Mat. Appl. 30 (2019), 437-478 -- see also arXiv:1804.11290), the same authors have studied viscous…

偏微分方程分析 · 数学 2020-07-10 Pierluigi Colli , Gianni Gilardi , Jürgen Sprekels

We analyze a phase field model for tumor growth consisting of a Cahn-Hilliard-Brinkman system, ruling the evolution of the tumor mass, coupled with an advection-reaction-diffusion equation for a chemical species acting as a nutrient. The…

偏微分方程分析 · 数学 2023-07-26 Pierluigi Colli , Gianni Gilardi , Andrea Signori , Jürgen Sprekels

Mechanical effects have mostly been neglected so far in phase field tumour models that are based on a Cahn-Hilliard approach. In this paper we study a macroscopic mechanical model for tumour growth in which cell-cell adhesion effects are…

偏微分方程分析 · 数学 2021-01-20 Harald Garcke , Kei Fong Lam , Andrea Signori

We consider a phase-field system modelling solid tumour growth. This system consists of a Cahn-Hilliard equation coupled with a nutrient equation. The former is characterised by a degenerate mobility and a singular potential. Both equations…

偏微分方程分析 · 数学 2025-12-18 Cecilia Cavaterra , Matteo Fornoni , Maurizio Grasselli , Benoît Perthame

In this paper, we study a phase field model for a tumor growth model of Cahn--Hilliard type in which the often assumed parabolic relaxation of the chemical potential is replaced by a hyperbolic one. We show that the resulting…

偏微分方程分析 · 数学 2026-02-16 Pierluigi Colli , Elisabetta Rocca , Jürgen Sprekels

This article considers a limit system by passing to the limit in the following Cahn--Hilliard type phase field system related to tumor growth as $\beta\searrow0$: \begin{equation*} \begin{cases} \alpha\partial_{t} \mu_{\beta} + \partial_{t}…

偏微分方程分析 · 数学 2019-05-01 Shunsuke Kurima

We introduce a new diffuse interface model for tumour growth in the presence of a nutrient, in which we take into account mechanical effects and reversible tissue damage. The highly nonlinear PDEs system mainly consists of a Cahn-Hilliard…

偏微分方程分析 · 数学 2025-10-09 Giulia Cavalleri

A distributed optimal control problem for a phase field system which physical context is that of tumor growth is discussed. The system we are going to take into account consists of a Cahn-Hilliard equation for the phase variable (relative…

偏微分方程分析 · 数学 2021-01-20 Andrea Signori

We consider a diffuse interface model for tumor growth consisting of a Cahn--Hilliard equation with source terms coupled to a reaction-diffusion equation, which models a tumor growing in the presence of a nutrient species and surrounded by…

偏微分方程分析 · 数学 2017-05-04 Harald Garcke , Kei Fong Lam

We study the Cahn-Hilliard-Biot model with respect to its mathematical well-posedness. The system models flow through deformable porous media in which the solid material has two phases with distinct material properties. The two phases of…

偏微分方程分析 · 数学 2024-10-04 Marvin Fritz

We investigate a multiphase Cahn-Hilliard model for tumor growth with general source terms. The multiphase approach allows us to consider multiple cell types and multiple chemical species (oxygen and/or nutrients) that are consumed by the…

偏微分方程分析 · 数学 2022-06-22 Patrik Knopf , Andrea Signori

In this paper, we study the longtime asymptotic behavior of a phase separation process occurring in a three-dimensional domain containing a fluid flow of given velocity. This process is modeled by a viscous convective Cahn-Hilliard system,…

偏微分方程分析 · 数学 2018-03-13 Pierluigi Colli , Gianni Gilardi , Jürgen Sprekels

We consider a diffuse interface model for tumour growth consisting of a Cahn--Hilliard equation with source terms coupled to a reaction-diffusion equation. The coupled system of partial differential equations models a tumour growing in the…

偏微分方程分析 · 数学 2016-05-26 Harald Garcke , Kei Fong Lam
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