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We investigate large-sample properties of treatment effect estimators under unknown interference in randomized experiments. The inferential target is a generalization of the average treatment effect estimand that marginalizes over potential…

统计理论 · 数学 2019-10-25 Fredrik Sävje , Peter M. Aronow , Michael G. Hudgens

Time plays a fundamental role in causal analyses, where the goal is to quantify the effect of a specific treatment on future outcomes. In a randomized experiment, times of treatment, and when outcomes are observed, are typically well…

统计方法学 · 统计学 2016-01-19 Guillaume W. Basse , Alexander Volfovsky , Edoardo M. Airoldi

The use and development of mobile interventions are experiencing rapid growth. In "just-in-time" mobile interventions, treatments are provided via a mobile device and they are intended to help an individual make healthy decisions "in the…

统计方法学 · 统计学 2020-07-23 Peng Liao , Predrag Klasnja , Ambuj Tewari , Susan A. Murphy

The global need for effective disease diagnosis remains substantial, given the complexities of various disease mechanisms and diverse patient symptoms. To tackle these challenges, researchers, physicians, and patients are turning to machine…

机器学习 · 计算机科学 2023-10-27 S M Atikur Rahman , Sifat Ibtisum , Ehsan Bazgir , Tumpa Barai

The dearth of prescribing guidelines for physicians is one key driver of the current opioid epidemic in the United States. In this work, we analyze medical and pharmaceutical claims data to draw insights on characteristics of patients who…

In many areas, practitioners seek to use observational data to learn a treatment assignment policy that satisfies application-specific constraints, such as budget, fairness, simplicity, or other functional form constraints. For example,…

统计理论 · 数学 2020-09-08 Susan Athey , Stefan Wager

A new meta-algorithm for estimating the conditional average treatment effects is proposed in the paper. The main idea underlying the algorithm is to consider a new dataset consisting of feature vectors produced by means of concatenation of…

机器学习 · 统计学 2019-09-10 Lev V. Utkin , Mikhail V. Kots , Viacheslav S. Chukanov

Intuitively, sampling is likely to be more efficient for prevalence estimation, if the cases (or positives) have a relatively higher representation in the sample than in the population. In case the virus is transmitted via personal…

应用统计 · 统计学 2020-11-18 Li-Chun Zhang

To maximize clinical benefit, clinicians routinely tailor treatment to the individual characteristics of each patient, where individualized treatment rules are needed and are of significant research interest to statisticians. In the…

统计方法学 · 统计学 2021-11-23 Trinetri Ghosh , Yanyuan Ma , Rui Song , Pingshou Zhong

Tech companies (e.g., Google or Facebook) often use randomized online experiments and/or A/B testing primarily based on the average treatment effects to compare their new product with an old one. However, it is also critically important to…

统计方法学 · 统计学 2021-11-09 Chengchun Shi , Shikai Luo , Hongtu Zhu , Rui Song

In this paper, we address the issue of estimating and inferring distributional treatment effects in randomized experiments. The distributional treatment effect provides a more comprehensive understanding of treatment heterogeneity compared…

计量经济学 · 经济学 2025-01-15 Tatsushi Oka , Shota Yasui , Yuta Hayakawa , Undral Byambadalai

Personalized medicine aims at identifying best treatments for a patient with given characteristics. It has been shown in the literature that these methods can lead to great improvements in medicine compared to traditional methods…

The emergence and continued reliance on the Internet and related technologies has resulted in the generation of large amounts of data that can be made available for analyses. However, humans do not possess the cognitive capabilities to…

机器学习 · 计算机科学 2021-01-12 MohammadNoor Injadat , Abdallah Moubayed , Ali Bou Nassif , Abdallah Shami

Research on decision support applications in healthcare, such as those related to diagnosis, prediction, treatment planning, etc., have seen enormously increased interest recently. This development is thanks to the increase in data…

机器学习 · 计算机科学 2021-03-25 Jussi Tohka , Mark van Gils

Understanding treatment effect heterogeneity is vital to many scientific fields because the same treatment may affect different individuals differently. Quantile regression provides a natural framework for modeling such heterogeneity. We…

统计方法学 · 统计学 2023-07-12 Alexander Giessing , Jingshen Wang

Pragmatic randomized trials are designed to provide evidence for clinical decision-making rather than regulatory approval. Common features of these trials include the inclusion of heterogeneous or diverse patient populations in a wide range…

统计方法学 · 统计学 2019-11-20 Eleanor J. Murray , Sonja A. Swanson , Miguel A. Hernán

Observational cohort studies are increasingly being used for comparative effectiveness research to assess the safety of therapeutics. Recently, various doubly robust methods have been proposed for average treatment effect estimation by…

统计方法学 · 统计学 2025-03-11 Xiaoqing Tan , Shu Yang , Wenyu Ye , Douglas E. Faries , Ilya Lipkovich , Zbigniew Kadziola

Interference occurs when the potential outcomes of a unit depend on the treatment of others. Interference can be highly heterogeneous, where treating certain individuals might have a larger effect on the population's overall outcome. A…

统计方法学 · 统计学 2025-04-11 Samantha G Dean , Georgia Papadogeorgou , Laura Forastiere

We propose a new problem formulation which is similar to, but more informative than, the binary multiple-instance learning problem. In this setting, we are given groups of instances (described by feature vectors) along with estimates of the…

机器学习 · 计算机科学 2012-07-09 Hendrik Kuck , Nando de Freitas

Recently, a number of drug-therapy, disease, drug, and drug-target networks have been introduced. Here we suggest novel methods for network-based prediction of novel drug targets and for improvement of drug efficiency by analysing the…

分子网络 · 定量生物学 2008-07-31 Zoltan Spiro , Istvan A. Kovacs , Peter Csermely
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