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Deep brain stimulation (DBS) is a surgical treatment for Parkinson's Disease. Static models based on quasi-static approximation are common approaches for DBS modeling. While this simplification has been validated for bioelectric sources,…

神经元与认知 · 定量生物学 2016-08-18 Pablo A. Alvarado , Mauricio A. Álvarez , Álvaro A. Orozco

Hemispheric strokes impair motor control in contralateral body parts, necessitating effective rehabilitation strategies. Motor Imagery-based Brain-Computer Interfaces (MI-BCIs) promote neuroplasticity, aiding the recovery of motor…

信号处理 · 电气工程与系统科学 2025-01-06 Praveen K. Parashiva , Sagila Gangadaran , A. P. Vinod

Can Neural Assemblies -- groups of neurons that fire together and strengthen through co-activation -- learn the direction of causal influence between variables? While established as a computationally general substrate for classification,…

机器学习 · 计算机科学 2026-04-30 Evangelia Kopadi , Dimitris Kalles

The paper highlights the role of a positive feedback gating mechanism at the cellular level in the robust- ness and modulation properties of rhythmic activities at the circuit level. The results are presented in the context of half-center…

神经元与认知 · 定量生物学 2014-12-22 Julie Dethier , Guillaume Drion , Alessio Franci , Rodolphe Sepulchre

Mental disorders (MD) are among the top most demanding challenges in world-wide health. According to the World Health Organization, the burden of MDs continues to grow with significant impact on health and major social and human rights. A…

神经元与认知 · 定量生物学 2023-03-21 Thomas Wahl , Joséphine Riedinger , Michel Duprez , Axel Hutt

The ultimate goal of cognitive neuroscience is to understand the mechanistic neural processes underlying the functional organization of the brain. Key to this study is understanding structure of both the structural and functional…

神经元与认知 · 定量生物学 2022-02-10 Jeremie Fish , Alexander DeWitt , Abd AlRahman R. AlMomani , Paul J. Laurienti , Erik Bollt

Suppression of excessively synchronous beta-band oscillatory activity in the brain is believed to suppress hypokinetic motor symptoms of Parkinson's disease. Recently, a lot of interest has been devoted to desynchronizing delayed feedback…

神经元与认知 · 定量生物学 2013-03-05 Andrey Dovzhenok , Choongseok Park , Robert M. Worth , Leonid L. Rubchinsky

Cable-Driven Continuum Manipulators (CDCMs) enable scar-free procedures but face limitations in workspace and control accuracy due to hysteresis. We introduce an extensible CDCM with a Semi-active Mechanism (SAM) and develop a real-time…

机器人学 · 计算机科学 2025-05-08 Junhyun Park , Seonghyeok Jang , Myeongbo Park , Hyojae Park , Jeonghyeon Yoon , Minho Hwang

In recent years, there have been increasing concerns about how geomagnetic disturbances (GMDs) impact electrical power systems. Geomagnetically-induced currents (GICs) can saturate transformers, induce hot spot heating and increase reactive…

系统与控制 · 计算机科学 2017-10-06 Mowen Lu , Harsha Nagarajan , Emre Yamangil , Russell Bent , Scott Backhaus , Arthur Barnes

Traumatic Brain Injuries (TBIs) resulting from Road Traffic Crashes (RTCs) can have fatal and disabling effects on patients. In this study, we evaluated the TBIs outcomes of patients involved in RTCs and identify key contributing factors…

应用统计 · 统计学 2024-11-05 Azka Rodoshi Oishi , Md Jamil Ahsan , Azka Sejuti , B M Tazbiul Hassan Anik

Prevention of secondary brain injury is a core aim of neurocritical care, with Spreading Depolarizations (SDs) recognized as a significant independent cause. SDs are typically monitored through invasive, high-frequency electrocorticography…

信号处理 · 电气工程与系统科学 2025-05-20 Jeanne Boyer-Chammard , Yinzhe Wu , Chenyu Zhang , Sharon Jewell , Anthony Strong , Guang Yang , Martyn Boutelle

Motivation to perform movement therapy and caregiver burnout are major challenges to post-stroke life. Serious games have been shown to support therapeutic tasks in people with stroke, but there are few activities that simultaneously…

Autism spectrum disorder (ASD) is one of the major developmental disorders affecting children. Recently, it has been hypothesized that ASD is associated with atypical brain connectivities. A substantial body of researches use Pearson's…

神经元与认知 · 定量生物学 2019-03-06 Biwei Huang , Kun Zhang , Ruben Sanchez-Romero , Joseph Ramsey , Madelyn Glymour , Clark Glymour

Understanding brain dynamics and functions critically depends on knowledge of the network connectivity among neurons. However, the complexity of brain structural connectivity, coupled with continuous modifications driven by synaptic…

神经元与认知 · 定量生物学 2025-07-04 Kai Chen , Mingzhang Wang , Songting Li , Douglas Zhou

Neuroscientific evidence shows that for most brain networks all pathways between cortical regions either pass through the thalamus or a transthalamic parallel route exists for any direct corticocortical connection. This paper seeks to…

神经元与认知 · 定量生物学 2022-07-12 Michael McCreesh , Jorge Cortés

Research in blast-induced lung injury resulted in exposure thresholds that are useful in understanding and protecting humans from such injury. Because traumatic brain injury (TBI) due to blast exposure has become a prominent medical and…

医学物理 · 物理学 2011-02-09 Michael Courtney , Amy Courtney

Cortical slow oscillations occur in the mammalian brain during deep sleep and have been shown to contribute to memory consolidation, an effect that can be enhanced by electrical stimulation. As the precise underlying working mechanisms are…

神经元与认知 · 定量生物学 2013-12-31 Arne Weigenand , Thomas Martinetz , Jens Christian Claussen

In tendon driven continuum manipulators (TDCMs), reconfiguring the tendon routing enables tailored spatial deformation of the backbone. This work presents a design in which tendons can be rerouted either prior to or after actuation by…

机器人学 · 计算机科学 2026-04-15 Sabyasachi Dash , John Golden , Girish Krishnan

Evidence suggests that disruptions of the posteromedial cortex (PMC) and posteromedial corticothalamic connectivity contribute to disorders of consciousness (DOCs). While most previous studies treated the PMC as a whole, this structure is…

神经元与认知 · 定量生物学 2018-05-28 Yue Cui , Ming Song , Darren M. Lipnicki , Yi Yang , Chuyang Ye , Lingzhong Fan , Jing Sui , Tianzi Jiang , Jianghong He

Noninvasive brain stimulation (NIBS) encompasses transcranial stimulation techniques that can influence brain excitability. These techniques have the potential to treat conditions like depression, anxiety, and chronic pain, and to provide…

数字图书馆 · 计算机科学 2023-10-11 Swathi Anil , Jennifer D'Souza