相关论文: How transcranial direct current stimulation facili…
The mechanism of the unconventional topological superconductivity (TSC) remains a long-standing issue. We investigate the quantum phase diagram of the extended $t$-$J$-$J_{\chi}$ model including spin chiral interactions on triangular…
Majority of stroke survivors are left with poorly functioning paretic hands. Current rehabilitation devices have failed to motivate the patients enough to continue rehabilitation exercises. The objective of this project, MIDAS…
Traumatic Brain Injury (TBI) results from an impact or concussion to the head with the injury being specifically characterized through pathological degradation at various biological length scales. Following injury, various mechanical…
Closed-loop neural stimulation provides novel therapies for neurological diseases such as Parkinson's disease (PD), but it is not yet clear whether artificial intelligence (AI) techniques can tailor closed-loop stimulation to individual…
Synthetic molecular communication (SMC) is a key enabler for future healthcare systems in which Internet of Bio-Nano-Things (IoBNT) devices facilitate the continuous monitoring of a patient's biochemical signals. To close the loop between…
Cluster synchronization underlies various functions in the brain. Abnormal patterns of cluster synchronization are often associated with neurological disorders. Deep brain stimulation (DBS) is a neurosurgical technique used to treat several…
Brain dynamics can exhibit narrow-band nonlinear oscillations and multistability. For a subset of disorders of consciousness and motor control, we hypothesize that some symptoms originate from the inability to spontaneously transition from…
Spreading depolarization (SD) is a self-propagating wave of near-complete neuronal depolarization that is abundant in a wide range of neurological conditions, including stroke. SD was only recently documented in humans and is now considered…
Recovery after stroke is often incomplete, but rehabilitation training may potentiate recovery by engaging endogenous neuroplasticity. In preclinical models of stroke, high doses of rehabilitation training are required to restore functional…
Cerebrovascular dynamics and pathomechanisms that evolve in the minutes and hours following traumatic vascular injury in the brain remain largely unknown. We investigated the pathophysiology evolution within the first three hours after…
Global brain activity self-organizes into discrete patterns characterized by distinct behavioral observables and modes of information processing. The human thalamocortical system is a densely connected network where local neural activation…
Network control theory (NCT) has recently been utilized in neuroscience to facilitate our understanding of brain stimulation effects. A particularly useful branch of NCT is optimal control, which focuses on applying theoretical and…
Structural and functional MRI studies of patients with post-stroke language deficits have contributed substantially to our understanding of how cognitive-behavioral impairments relate to the location of structural damage and to the…
Truncus arteriosus (TA) is a rare and severe congenital heart disease. Quadricuspid valve morphology occurs in 25% of all TA patients and is linked to regurgitation and increased risk of re-operation. It remains unclear how hemodynamic…
Traumatic brain injury is a global public health problem associated with chronic neurological complications and long-term disability. Biomarkers that map onto the underlying brain pathology driving these complications are urgently needed to…
Since the earliest electroencephalography experiments, large scale oscillations have been observed in the mammalian brain. More recently, episodes of oscillation and bursting have been identified not only in the cerebral cortex and…
Understanding how few distributed areas can steer large-scale brain activity is a fundamental question that has practical implications, which range from inducing specific patterns of behavior to counteracting disease. Recent endeavors based…
Decoding motor performance from brain signals offers promising avenues for adaptive deep brain stimulation (aDBS) for Parkinson's disease (PD). In a two-center cohort of 19 PD patients executing a drawing task, we decoded motor performance…
The topological superconducting state is a highly sought-after quantum state hosting topological order and Majorana excitations. In this work, we explore the mechanism to realize the topological superconductivity (TSC) in the doped Mott…
The interaction between excitation and inhibition is crucial for brain computation. To understand synaptic mechanisms underlying brain function, it is important to separate excitatory and inhibitory inputs to a target neuron. In the…